DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	505	Identity:	171/505 - (33%)
Similarity:	261/505 - (51%)	Gaps:	58/505 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVGG 104
            ||.:|:|...|::..||..||||||.:.::.:.|.|..:.||..:|.|...::||..|::|.|||
Zfish    12 LLFSLSTAVIGSLQFGYNTGVINAPEQKLRAFFNATWMERYGEPISPGVCTIVWSFAVAIFSVGG 76

  Fly   105 AIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLP 169
            ..||......||||||:...::...|..:|..|...|...||.||::.||.::||..||.|...|
Zfish    77 MAGSFSVGVVANKFGRRKSMILVNVLALIGGGLMGLCTLCSSFEMIIAGRLMIGLFCGLFTGLTP 141

  Fly   170 MYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMF-LILVCYLPSY 233
            ||:.||:|..|||..|....:||..|:::.|:..|.::.|::.||...|...:. .||.|:|..:
Zfish   142 MYVGEVSPTPLRGAFGTLHQLGVVVGILIAQIFGLESLLGSDKLWPILLALTILPAILQCFLLPF 206

  Fly   234 LFPESPKFLYIVKGNRAAAKRELQRLR-----GKDAEELIAQEMAEMEAESNAKVQTSSFCDVLR 293
            . ||||::|.|.......|::.|.|||     |||.:|: .:|.|:|..|....:.     ::.|
Zfish   207 C-PESPRYLLINLNEEEQARKALVRLRGYEDVGKDMQEM-KEESAKMAMEKKVTIP-----ELFR 264

  Fly   294 DPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWL 358
            ......||.|.......||||||||:||||..||:.||::  ...:|.:|||.:|...:::..:|
Zfish   265 SAAYRQPLFIAIMLQLSQQLSGINAVFYYSTGIFKSAGVT--QPIYATIGAGVVNTVFTVVSLFL 327

  Fly   359 MAKCNRRTL-------MMFSCALCSVFLFTIAFVLFY---------------------------- 388
            :.:..||||       |..|....::.|..:.|.:.:
Zfish   328 VERAGRRTLHLIGLGGMAISALAMTIALLLVRFTVCFNFVKILNQPQQYLMIMVNVFITFVSKQK 392

  Fly   389 -IDQVSWFAIACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGIS 452
             |:.:.:.:||   .|..::..::.|.||||:||.||||...||..||::...::||.|||:||:
Zfish   393 DIEALQYLSIA---AIFAFVAMFEMGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTANFIVGIT 454

  Fly   453 FPLLQNAWGAFVFLPFSITCVLLFLLTKFYLPETRGRDPSEVAPLVSKGF 502
            ||.|:...|.:||:.|.|..::.|:.|.|.:|||:||...|:|    :||
Zfish   455 FPKLEELCGPYVFIIFMIFLIIFFIFTYFKVPETKGRTFDEIA----RGF 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	164/483 (34%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	140/427 (33%)
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	166/497 (33%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	135/411 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576905
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.800