DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and slc2a2

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001036186.1	Gene:	slc2a2 / 322493	ZFINID:	ZDB-GENE-030131-1213	Length:	504	Species:	Danio rerio

Alignment Length:	493	Identity:	158/493 - (32%)
Similarity:	253/493 - (51%)	Gaps:	48/493 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QKPRWGNLLLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNL--SAGG----- 88
            :|...|.|.|.|..|..  |::..||.:||||||.|:::....::| ..|..:|  |.||
Zfish     2 EKQLTGTLALAVFTAAL--GSLQMGYSLGVINAPQKVIERHYARSL-GVYNEDLARSEGGNGTEH 63

  Fly    89 -------LDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASS 146
                   :.:.||..|::|.|||.:.|...:...:..||....|....|.....:|....:..:.
Zfish    64 EKPTDPSVVMYWSLSVAIFSVGGMLSSFLVSFVGDFRGRIKGMLAINVLAITAGLLMGLAKMGTP 128

  Fly   147 VEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTE 211
            ..|::.||.::||..||.:..:|:|:.|::|:..||.:|....:.:..|:::.||..|..:.|.:
Zfish   129 HLMVIAGRAIMGLYCGLSSGLVPLYIGEISPVKYRGAMGALHQLAIVIGILISQVIGLDFLLGND 193

  Fly   212 DLWHYAL-------TAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIA 269
            .:||..|       .....|:|||       ||||::|||.:|....|.:.|:||:| |.:  .:
Zfish   194 YMWHILLGLSGAPAILQSLLLLVC-------PESPRYLYIKQGKVEDACKSLKRLKG-DYD--TS 248

  Fly   270 QEMAEMEAESNAKVQTS--SFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGL 332
            :::|||:||....::.:  |...:||.......|.:....|..||.||||||||||.|||:.||:
Zfish   249 KDIAEMKAEKEEAMKEAKMSILRLLRSSVYRQQLFVALMMHFSQQFSGINAIFYYSTSIFQTAGV 313

  Fly   333 STVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCA--LCSVFLFTIAFVLFYIDQVSWF 395
            .  ...:|.:|.|.:|:..:|:...::.:..||||.:....  .|.....|:.  |.:....||.
Zfish   314 G--QPVYATIGVGVVNIIFTLVSVLMVDRAGRRTLTLVGLGGMCCCAVAMTVG--LAFQGAYSWM 374

  Fly   396 AIACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAW 460
            :...:|.|..::.|::.|.||||:||.||:|...||..|:::....:||||||:|:.||.|.:..
Zfish   375 SYVSMVAIFMFVSFFEIGPGPIPWFIVAEIFSQGPRPAAIALAGFCNWTCNFIVGMVFPYLVSLC 439

  Fly   461 GAFVFLPFSITCVLLF---LLTKFYLPETRGRDPSEVA 495
            |::||:.|:   ||||   |...|.:|||:|:...|:|
Zfish   440 GSYVFIVFA---VLLFGFTLFIYFRVPETKGKTFEEIA 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	151/469 (32%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	127/399 (32%)
slc2a2	NP_001036186.1	Sugar_tr	12..477	CDD:278511	154/483 (32%)
slc2a2	NP_001036186.1	MFS	76..462	CDD:119392	129/402 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900