Protein Alignment sut1 and SLC37A4

DIOPT Version :10

• Sequence 1: NP_523658.1
• Gene: sut1 / 35774
• FlyBaseID: FBgn0028563
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001157750.1
• Gene: SLC37A4 / 2542
• HGNCID: 4061
• Length: 451
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 97/422 - (22%)
• Similarity: 151/422 - (35%)
• Gaps: 85/422 - (20%)

  Fly   102 VGGAIGSLGGAGAANKF-------GRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGL 159
            :|....|...|.|.:||       ...|.:|....|..||.|..||. .:|:|.:.....|:.||
Human    49 LGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFA-WSSTVPVFAALWFLNGL 112

  Fly   160 ASGLVTATLPMYLSEVAPMALRGTLGVFI--AVGVTGGVVVGQVCSLANVFGTEDLWHYALT-AY 221
            |.||........|.:....:..||....:  ::.:.||  :|.:  ||.:......|...|. :.
Human   113 AQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGG--LGPI--LATILAQSYSWRSTLALSG 173

  Fly   222 MFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAESNAKVQTS 286
            ...::|.:|...|....|..:    |.|.......:..:|...||...||:.           .|
Human   174 ALCVVVSFLCLLLIHNEPADV----GLRNLDPMPSEGKKGSLKEESTLQELL-----------LS 223

  Fly   287 SFCDVLRDPRLTLPLIIVCCFHGGQ----QLSGINAIFYYS-VSIFEKAGLSTVDAQWANLGAGC 346
            .:..||....|.:..:..||...||    |..|.:|:...| :|..|..||         :|
Human   224 PYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGL---------VG--- 276

  Fly   347 LNLAVSLLGPWLMAKCN-------RRTLMMFSCA--LCSVFLFTIAFVLFYIDQVSWFAIA---- 398
             ::|...|....|||..       |..|::|..|  ..|::||.:.........|:::.:|
Human   277 -SIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKDVAFWTLALHPL 340

  Fly   399 ----------CIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISF 453
                      ..:.::|.:|.:. ..|||..| |....|.||.::.        .|.:.|:|
Human   341 AELTGFTEHELWILVLGAVFGFS-SYGPIALF-GVIANESAPPNLC--------GTSHAIVG--- 392

  Fly   454 PLLQNAWGAFVFLPFSITCVLLFLLTKFYLPE 485
             |:.|..|....||||.........|.|::.|
Human   393 -LMANVGGFLAGLPFSTIAKHYSWSTAFWVAE 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	MFS_GLUT_Class1_2_like	48..489	CDD:340915	97/422 (23%)
SLC37A4	NP_001157750.1	MFS_SLC37A4	10..439	CDD:340901	97/422 (23%)