DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and Slc22a2

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_038695.1	Gene:	Slc22a2 / 20518	MGIID:	1335072	Length:	553	Species:	Mus musculus

Alignment Length:	479	Identity:	113/479 - (23%)
Similarity:	190/479 - (39%)	Gaps:	114/479 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LHDTYGSNL---------SAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALF 131
            ::||.||::         .:..|||..|.|    .||..||::|....|::||||.|.|:...:.
Mouse   127 VYDTPGSSIVTEFNLVCAHSWMLDLFQSLV----NVGFFIGAVGIGYLADRFGRKFCLLVTILIN 187

  Fly   132 TVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGV 196
            .:..||.   ..:.:...:::.||:.||.|........:.::|...:..|.|:|:...:..|.|:
Mouse   188 AISGVLM---AISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGL 249

  Fly   197 VVGQVCSLANVFGTEDLWHYALTAYMFLILVCYLPSYLF-------PESPKFLYIVKGNRAAAK- 253
            ::     ||.|       .|||..:.:|.....||::.|       ||||::|.....|..|.|
Mouse   250 LI-----LAGV-------AYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKI 302

  Fly   254 -RELQRLRGKDA----EELIAQEMAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIV--------- 304
             :.:.:..||..    :.|.|.|...|:.       ..||.|::|.|::....:|:
Mouse   303 IKHIAKKNGKSVPVSLQSLTADEDTGMKL-------NPSFLDLVRTPQIRKHTLILMYNWFTSSV 360

  Fly   305 ----CCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLG---PWLMAKC 362
                ...|.|.....|...|:||..:...|....:             |.:..:|   ||.::
Mouse   361 LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIII-------------LTIDRIGRRYPWAVS-- 410

  Fly   363 NRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCI--MGYIFFYQFGLGPIPYFIGAEL 425
               .::..:..|.|||:         .|.:.|..|. :.|:  ||....|:     :...:.|||
Mouse   411 ---NMVAGAACLASVFI---------PDDLQWLKIT-VACLGRMGITIAYE-----MVCLVNAEL 457

  Fly   426 FEVAPRSVAMSMGSLASWTCNFIIGISFPL----LQNAWGAFVFLPFSITCVL---LFLLTKFYL 483
            :....|::|:   .:.|..|: |.||..|.    |.:.|..|..:.|::..::   |.||    |
Mouse   458 YPTYIRNLAV---LVCSSMCD-IGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLL----L 514

  Fly   484 PETRGRDPSEVAPLVSKGFRSKVK 507
            |||:|:...|......|..|.:.|
Mouse   515 PETKGKALPETIEDAEKMQRPRKK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	110/467 (24%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	96/423 (23%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	109/464 (23%)
Slc22a2	NP_038695.1	MFS	125..492	CDD:119392	98/427 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920