DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and R09B5.11

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_503413.2	Gene:	R09B5.11 / 178634	WormBaseID:	WBGene00019979	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	150/512 - (29%)
Similarity:	245/512 - (47%)	Gaps:	57/512 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KSQPAEAQQLYPQPNRVELLSAQTDPSQKPRWGNLLLL----VALATTFGGAVSTGYCIGVINAP 64
            ||:.....|..|..|                |...|..    :|||     :...|:.||.||||
Worm    28 KSEKENHHQSLPDEN----------------WTPFLFFCISSIALA-----SFQDGFQIGCINAP 71

  Fly    65 SKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGA 129
            ..|:..|..:...:.:|..||....|.:||..||:|.|||..||......|:|||||:..|....
Worm    72 GPLIIDWIKKCHFELFGEVLSQYQADFIWSVAVSMFSVGGMFGSFCSGFLADKFGRKSTLLYNNI 136

  Fly   130 LFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTG 194
            |..:.||.....:..:...|:|.|||:|||..|:.:..:||:|:|:||..|||..|.|..:.::.
Worm   137 LALLAAVCLSTSKLFNFYPMIVFGRFLVGLNCGITSGLVPMFLTELAPANLRGKCGSFHQLNISV 201

  Fly   195 GVVVGQVCSLANVFGTEDLWHYALTAYMFLILVCY-LPSYL----FP---ESPKFLYIVKGNRAA 251
            .:|:.|...|..:|||:..|.|        |..|. :|::|    .|   ||||:|.....:|..
Worm   202 AIVLSQALGLPQIFGTQVGWPY--------IFACVAIPTFLQLATIPFCVESPKYLISKLNDREE 258

  Fly   252 AKRELQRLRG-----KDAEELIAQEMAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIVCCFHGGQ 311
            |:|.|::|||     ::.|.::.:.|..:|     .:....:..:.:... ..|:|:.......|
Worm   259 ARRILEKLRGHTKVDEELEHMVQETMVTVE-----PLHQPGYVSLFKGDN-QWPMIVSILMMFSQ 317

  Fly   312 QLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLM--AKCNRRTLMMFSCA- 373
            |.|||:|:.:||..||::.|||..:..:|.:|.||:.|..:....:|:  .|..|:.|.:...:
Worm   318 QFSGISAVTFYSTLIFKRNGLSGNEPMYATVGFGCIKLIATFGCLFLIDHPKFGRKRLHIAGLSG 382

  Fly   374 LC-SVFLFTIAFVLFYIDQVSWFAIACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSM 437
            :| |..|..|...|.... ..|.:...::.|:.::..:.||.||||:|..:|||:.|.|..|.::
Worm   383 MCISSILIVITLTLSNAG-YHWASYMNVLFILSFVVTFAFGPGPIPWFFTSELFDSATRGRAAAV 446

  Fly   438 GSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLFLLTKFYLPETRGRDPSEV 494
            .:.::|..|:::|::|..:.|....:.||.|:.......:.|..::|||:|:.||.:
Worm   447 SATSNWVANWMVGLTFLPINNIIHQYAFLMFTFFTFTFAIFTWKFVPETKGKSPSAI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	140/457 (31%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	119/402 (30%)
R09B5.11	NP_503413.2	Sugar_tr	54..499	CDD:278511	141/464 (30%)
R09B5.11	NP_503413.2	MFS	90..465	CDD:119392	119/389 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I2266
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.870