DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	490	Identity:	154/490 - (31%)
Similarity:	249/490 - (50%)	Gaps:	13/490 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LSAQTDPSQKPRWGNLLLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAG 87
            ||......:..:|...|::.||...||.:...||.:.|:|||:..:|.:.|.|.:..:|..:...
Mouse    21 LSVGHQQRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQPIDPD 85

  Fly    88 GLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCR-AASSVEMLV 151
            .|.||||..||:|.:||.:|:|.........|||:..|:... |.:.|.|...|. .|.:.|||:
Mouse    86 TLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKSTLLVNNG-FAISAALLMACSLRAGTFEMLI 149

  Fly   152 IGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHY 216
            :|||::|:..|:..:.|||||:|::|..:||:||...|:.:..||..||:..|..:.|.|..|.|
Mouse   150 VGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGRESTWPY 214

  Fly   217 ALTAYMF--LILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAES 279
            .....:.  |:.:..||  ..||||::|...|.:.|.|.:..|...|| |:  ::||:.|..|||
Mouse   215 LFGVIIVPALVQLASLP--FLPESPRYLLFEKHDEAGAMKAFQTFLGK-AD--VSQELEEALAES 274

  Fly   280 NAK--VQTSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANL 342
            ..:  ::..|..::||.|.:...:|.|.......||.|:|||::|:.|||.|||:......:..|
Mouse   275 RVQRNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIWFYTNSIFGKAGIPQDKIPYITL 339

  Fly   343 GAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYI 407
            ..|.:....::....::.:..||.|::....|.::|..|:...|...||..|.....||||:..|
Mouse   340 STGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGTLTATLTLQDQAPWVPYLSIVCILAII 404

  Fly   408 FFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITC 472
            ..:..|.|.||:.:..|.|:.:.|..|..:....:|..||.:|:.||.:|.:..::.||.|:..|
Mouse   405 ASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFPFIQKSLDSYCFLVFATIC 469

  Fly   473 VLLFLLTKFYLPETRGRDPSEVAPLVSKGFRSKVK 507
            :.......|.||||:.|..:|::...:|  |:|.:
Mouse   470 IAGATYFYFVLPETKNRTHAEISQAFAK--RNKAQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	143/446 (32%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	121/390 (31%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	146/456 (32%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538		3/10 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	320	1.000	Inparanoid score	I2506
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.800