DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and slc2a4

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	487	Identity:	166/487 - (34%)
Similarity:	256/487 - (52%)	Gaps:	46/487 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGG-------LDLLWSCVV 97
            |::::.|...|:...||.|||||||.|:::    |:.::::.|..|:|.       |..|||..|
Frog    24 LVLSVFTAILGSFQFGYNIGVINAPQKIIE----QSYNESWISRSSSGSASIDPGLLRTLWSLSV 84

  Fly    98 SVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASG 162
            ::|.:||.:.||.....:...|||...:|......:........:...|.||:::|||::|:.||
Frog    85 AIFSIGGMVSSLSVGVVSQWLGRKRAMVINNVFAFLAGSFMGLSQVCQSYEMMIVGRFLIGVYSG 149

  Fly   163 LVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLILV 227
            |.:..:|||:.|::|..|||.:|....:.:..|::|.||..|....||...|    .|..::.|:
Frog   150 LASGLVPMYVGEISPTHLRGAMGTLHQLSLVIGILVAQVLGLELFLGTNTRW----PALFWVTLI 210

  Fly   228 -----CYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAE-----SNAK 282
                 |.:..:. ||||:|||||....|.||:.|:||.|...   :..::::|:.|     |..|
Frog   211 PAALQCLMLPFC-PESPRFLYIVCEQEAQAKKSLRRLTGLPD---VTDDLSDMKEEKRQMDSEPK 271

  Fly   283 VQTSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCL 347
            |   |...:.|......|:::.......|||||||||||||..||.|||:.  ...:|.:|||.:
Frog   272 V---SILQIFRSRNYRQPILVAIVLQLSQQLSGINAIFYYSTDIFSKAGVE--QPIYATIGAGIV 331

  Fly   348 NLAVSLLGPWLMAKCNRRTLMMFSCA---LCSVFLFTIAFVL-FYIDQVSWFAIACIVCIMGYIF 408
            |.|.:::..:|:.:..||||.:...|   :|:: |.|.|.|| ..:..:|:.::|   .|.|::.
Frog   332 NTAFTVVSLFLVERAGRRTLQLLGLAGMIVCAL-LMTAAMVLQESVPSLSYLSMA---AIFGFVA 392

  Fly   409 FYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCV 473
            |::.|.||||:||.||||...||..||::....:||.|||||:.|..:....|.:|||.|.....
Frog   393 FFEIGPGPIPWFIVAELFSQGPRPAAMAIAGCTNWTSNFIIGMGFQYVAELCGPYVFLLFGALLF 457

  Fly   474 LLFLLTKFYLPETRGRDPSEVAPLVSKGFRSK 505
            ...:.|.|.:||||||...|    :|..||.:
Frog   458 AFLIFTYFRVPETRGRSFDE----ISHAFRRR 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	160/462 (35%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	134/399 (34%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	159/467 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2586
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060