DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and slc2a9

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_002936818.2	Gene:	slc2a9 / 100495427	XenbaseID:	XB-GENE-5883703	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	482	Identity:	162/482 - (33%)
Similarity:	253/482 - (52%)	Gaps:	34/482 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GNL---LLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVV 97
            |||   ||.|:|.::||.::..||.:.|:|:||:.:|.:.|.|.:..||..|....|.|::|..|
Frog    15 GNLTFSLLAVSLLSSFGSSMLYGYNLAVVNSPSEYIKAFYNTTWNQRYGEALEQSPLTLMYSLTV 79

  Fly    98 SVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASG 162
            |||.:||.:|||......::||||...:....|..|...|....|..||.||::||||:.|:.||
Frog    80 SVFALGGMLGSLLVGILVSRFGRKGTIIRSTPLVFVAGGLMGLSRIFSSPEMVIIGRFITGIHSG 144

  Fly   163 LVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLILV 227
            :..:.:||||.|::|..|||.||:..::.:..||...||..|..:.|.::.|.      :||.||
Frog   145 ISLSVVPMYLGEISPKNLRGLLGLVPSIFICLGVFSAQVLGLPELLGQDETWP------LFLSLV 203

  Fly   228 CYLPSYL-------FPESPKFLYIVKGNRAAAKRELQRLRGK-DAEELIAQEMAEMEAESNAKVQ 284
             .:|:::       |||||::|.|.|.|.......|:...|: |.:::| :||.| |.:|.:.|.
Frog   204 -VVPTFVQLVLLPWFPESPRYLLIDKSNVHGTIDALRCFLGEYDVQDVI-EEMQE-EQKSFSSVD 265

  Fly   285 TSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNL 349
            |.|.|..|.||.|...::.|...:.|.|||||:||::|:.||||.||:...:..:..:|.|.:.:
Frog   266 TVSVCQFLSDPTLFWQILSVIVINIGMQLSGIDAIWFYTNSIFENAGIPMAEIPYTTVGTGAIEI 330

  Fly   350 AVSLLGPWLMAKCNRRTLMM-------FSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYI 407
            ...|:|.:.:.|..||.|::       |.||       .|...|.:..:|.......:.|::|.|
Frog   331 VAGLIGCFTVEKLGRRPLLIGGFSFMGFCCA-------GITLALVFQARVPVMRYVSVACVIGII 388

  Fly   408 FFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITC 472
            ..:..|...:|:.|..|||..:.|..|..:|...:|..||.:|..||.||.:.|||.::.|...|
Frog   389 AGFCIGPAGLPFIITGELFTQSHRPAAFIVGGTLNWLSNFTVGFVFPFLQISAGAFCYMVFCGIC 453

  Fly   473 VLLFLLTKFYLPETRGRDPSEVAPLVS 499
            :.:.....:.:|||:.|...|::.:.|
Frog   454 LFVAAYVYYIIPETKNRTFMEISLMFS 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	152/456 (33%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	132/400 (33%)
slc2a9	XP_002936818.2	MFS_GLUT_Class2	30..475	CDD:340990	153/460 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2586
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970