DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and slc22a2

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_002933908.1	Gene:	slc22a2 / 100487774	XenbaseID:	XB-GENE-965056	Length:	544	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	120/472 - (25%)
Similarity:	184/472 - (38%)	Gaps:	105/472 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 INAPSKLMKVWCNQTL-HDTYGS------NLSAGG---LDLLWSCVVSVFLVGGAIGSLGGAGAA 115
            :|..|||....|.... ::|.||      ||..|.   ||...|||...|.:||.|...    .|
Frog   102 LNITSKLPITNCKDGWDYNTTGSSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGY----IA 162

  Fly   116 NKFGRKACFLICGALFT-VGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMA 179
            ::||||. |||...|.| :..:|..|   |.:..::|..||:.|..|.....:..:.::|...:.
Frog   163 DRFGRKP-FLISSILITGIFGILMAF---APNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLE 223

  Fly   180 LRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLILVCYLPSYLF-------PE 237
            .|.|:|:......|.|:::     |:.|       .|.|..:.:|.:...:|.:.|       ||
Frog   224 HRRTVGIVYQAAFTVGLLL-----LSGV-------AYVLPHWRWLQMTVTIPYFFFLAYYWCVPE 276

  Fly   238 SPKFLYIVKGNRAAAK---RELQRLRGKDAEELIAQEMAEMEAESNAKVQTSSFCDVLRDPRL-- 297
            ||::| |.:..:|.||   ..:.:..||...:.:....|:.||   .:.|..||.|::|.|::
Frog   277 SPRWL-ISQNRKAEAKAIIHTIAKKNGKMVPDFLESLTADEEA---GEKQVPSFLDLVRTPQIRK 337

  Fly   298 -TLPLIIV---CC-------FHGGQQLSGINAIFYYSVSI-FEKAGL--STVDAQWANLGAGCLN 348
             ||.|:.:   |.       .|.|.....|...|:.|..: |..|.|  .|||
Frog   338 HTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISALVEFPSAILIIVTVD------------ 390

  Fly   349 LAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCI--MGYIFFYQ 411
             .|....|||:.              |.:...|.....|.....||..|. :.|:  ||....|:
Frog   391 -RVGRRYPWLVC--------------CIITGITCLITAFIPHGYSWLIIT-LSCVSRMGITVSYE 439

  Fly   412 FGLGPIPYFIGAELFEVAPRS----VAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITC 472
                 :...:.|||:....|:    |..||..|......||:    ..|...|.....:.|::..
Frog   440 -----MVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIV----YRLAAIWQELPLIVFAVLA 495

  Fly   473 VLLFLLTKFYLPETRGR 489
            .:..:|. ::||||:||
Frog   496 TVSGILV-YFLPETKGR 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	120/472 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	99/418 (24%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	120/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010