DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and slc2a6

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_031747426.1	Gene:	slc2a6 / 100485956	XenbaseID:	XB-GENE-5944908	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	546	Identity:	137/546 - (25%)
Similarity:	228/546 - (41%)	Gaps:	109/546 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPSQKPRWGN---------------------------LLLLVALAT-----TFGGAVSTGYCIGV 60
            |.||||..|:                           .:.|.|.:.     |||.|:.  |...|
Frog     2 DDSQKPLLGDGPKSHYQTVGKALREEEKKYVRTLKNKKMFLAAFSAVLGNFTFGYALV--YTSPV 64

  Fly    61 INAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFL 125
            |.|..|           |..|.::|..  ::.|  ..:||.:|...|.:......::.|||...:
Frog    65 IPALEK-----------DDQGLHISPE--EISW--FGAVFALGACAGGVSSMVLNDRLGRKLSIM 114

  Fly   126 ICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAV 190
            ......::|   |....:|..:.||::||.:.|.|.|:.::::|:|:||::...:||.||....:
Frog   115 FSAVPSSLG---FLLMGSAQHISMLLLGRILTGFAGGMTSSSIPVYISEISHSGVRGGLGACPQI 176

  Fly   191 -GVTGGVVVGQVCSLANVFGTEDLWHY-----ALTAYMFLILVCYLPSYLFPESPKFLYIVKGNR 249
             .|.|.:|:       ...|....|.:     .:.....|:|:|::     |:||:|| |.||..
Frog   177 MAVCGSLVL-------YALGLLLPWRWLAVIGEVPVITMLLLLCFM-----PDSPRFL-ISKGKD 228

  Fly   250 AAAKRELQRLRGKDAEELIAQEMAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIVCCFHGGQQLS 314
            ..|.:.|..|||.:.|  ...|...:::....|..|.|:.: |.:|....|::|.......||:|
Frog   229 EKALKALAWLRGVNTE--YQGEYERIKSNVLKKSSTLSWTE-LSNPYYYKPILIAVFMRFLQQMS 290

  Fly   315 GINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFL 379
            |::.|..|..:||.:..:.......|.| .|.:.|...::...:|.|..|:.|:..|    |:.:
Frog   291 GVSPILIYLETIFNRTKVILRGGYDAAL-VGAVRLLSVIISASVMDKAGRKILLFIS----SILM 350

  Fly   380 FTIA-----FVLFYID--------------------QVSWFAIACIVCIMGYIFFYQFGLGPIPY 419
            |..:     ::.|.:|                    .:::..:..:||||.||..|.||.|||.:
Frog   351 FASSLSMGLYIHFTVDGSHNSTNLTTITNSSADASEPINYIQLIPLVCIMLYIIGYAFGWGPITW 415

  Fly   420 FIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWG---AFVFLPFSITCVLLFLLTKF 481
            .:.:|:..:..|.||..:..|.||...||:..:|....||..   .|.|  |::.||.....|.|
Frog   416 LLMSEILPLKSRGVASGLCVLVSWITGFILTEAFIPAVNALSLETPFFF--FTVVCVGALFFTYF 478

  Fly   482 YLPETRGRDPSEVAPLVSKGFRSKVK 507
            ::|||:||...::......|.||.:|
Frog   479 FVPETKGRSLEQIEAYFRTGRRSFMK 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	121/475 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	106/419 (25%)
slc2a6	XP_031747426.1	MFS_GLUT6_Class3	41..490	CDD:340992	127/491 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910