Protein Alignment slv and SLC50A1

DIOPT Version :10

• Sequence 1: NP_477383.1
• Gene: slv / 35773
• FlyBaseID: FBgn0025469
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_061333.2
• Gene: SLC50A1 / 55974
• HGNCID: 30657
• Length: 221
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 60/209 - (28%)
• Similarity: 103/209 - (49%)
• Gaps: 3/209 - (1%)

  Fly     7 DSLLSTTAVISTVFQFLSGAMICRKYIQKKSTGDSSGVPFICGFLSCSFWLRYGVLTNEQSIVLV 71
            |||:....|:.|:..|.:|....|.....:|..:...:||:...::...||.||.|..:..:::|
Human     8 DSLIYGACVVFTLGMFSAGLSDLRHMRMTRSVDNVQFLPFLTTEVNNLGWLSYGALKGDGILIVV 72

  Fly    72 NIIGSTLFLVYTLIYYVFTVNKRACVKQFGFVLTVLVVVIVYTNRLEDQRDRMIHVTGIVCCIVT 136
            |.:|:.|..:|.|.|..:...||..:.|...:|.||::...|...|....:..:...|:.|.:.|
Human    73 NTVGAALQTLYILAYLHYCPRKRVVLLQTATLLGVLLLGYGYFWLLVPNPEARLQQLGLFCSVFT 137

  Fly   137 VCFFAAPLASLLHVIRAKNSESLPLPLIATSFVVSLQWLIYGILISDSFIQIPNFLGCILSLLQL 201
            :..:.:|||.|..||:.|:::.|..||...:.:.|..|.:||..:.|.:|.:.||.|.:.|.::.
Human   138 ISMYLSPLADLAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDPYIMVSNFPGIVTSFIRF 202

  Fly   202 GLFVLYP---PRSY 212
            .||..||   .|:|
Human   203 WLFWKYPQEQDRNY 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slv	NP_477383.1	MtN3_slv	8..94	CDD:397278	22/85 (26%)
		MtN3_slv	126..210	CDD:397278	27/86 (31%)
SLC50A1	NP_061333.2	MtN3_slv	9..95	CDD:397278	22/85 (26%)
		MtN3_slv	127..213	CDD:397278	27/85 (32%)
		Mediates interaction with TRPV2. /evidence=ECO:0000250	149..221		22/68 (32%)