Protein Alignment lig and Ubap2

DIOPT Version :9

• Sequence 1: NP_001260795.1
• Gene: lig / 35771
• FlyBaseID: FBgn0020279
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: XP_038965766.1
• Gene: Ubap2 / 313169
• RGDID: 1311717
• Length: 1135
• Species: Rattus norvegicus
• Alignment Length: 1322
• Identity: 355/1322 - (26%)
• Similarity: 513/1322 - (38%)
• Gaps: 357/1322 - (27%)

  Fly    65 ATTEQLRIAQITNSTTEDPQINEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLIEELPQGA 129
            ||.||:|:||:. ....|.....||..|:.:|.::::|...||::|:.|:
  Rat    40 ATAEQMRLAQVI-FDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDV--------------- 88

  Fly   130 FAKYEKKRKNKAANNTADGAAGDGDWADGNG-----------NADRREKSRNRSSNRGGTRGSSD 183
                     |||.|...:|::....|....|           |.:.|||...|.::||  ||:::
  Rat    89 ---------NKAINTLLEGSSDTTSWETVGGKKKNFGRESSENKENREKRTEREASRG--RGNNN 142

  Fly   184 SRGWRGRETRENERNQRESREPWSGQNAGQD--RGDDRANDNYRGQRNGGGRSGPGGGGRGGGFV 246
            .:|..|...||           :.|:..|.|  :||   ..:.||:|.           ||.||.
  Rat   143 RKGRGGSRGRE-----------FKGEENGVDCSQGD---KPSERGKRT-----------RGRGFG 182

  Fly   247 SRSGRGGGRMGGRTGGPRGDRGSGGPGGAYGSG-------RGGNANEDHHEVELWDNTIAQN-AE 303
            ...|||.||:..::.|..............|.|       ...|..::..|.....::|:|. ..
  Rat   183 RGRGRGAGRLSAQSMGTFNPADYSESMSTDGCGTKLVVWEAAQNGTDEGPEGLAKPHSISQELPS 247

  Fly   304 KQQQAHDDAW----GDWNNEEYEGSLKDSKVFTTSNLATQSAANVVSGTGASVTAV------PAA 358
            |.......||    .:|..|::...|.::||||.|:....:  :|..|....:.|:      |..
  Rat   248 KSSYGLKGAWKNSVEEWTAEDWTEDLSETKVFTASSAPADN--HVPPGQSIDLVALLHKPAPPTQ 310

  Fly   359 AGT----EISAPPGLEHQLVQQGSHLEESSSSGPAAVTP-----PATLS---GSATTPLLQYSAA 411
            |..    |.|...|....||...|.....::.|.|:.||     |.:||   ||....|.|....
  Rat   311 AAEVNSFETSQQQGFGQALVFTNSQHNNPTAPGTASSTPASSYSPQSLSSVLGSGFGELAQSKMV 375

  Fly   412 -VSN--------PP-----PQLQSQGTQSGAGTGASAAAGGGAGSTPSSFVSASPDTFSSAASAA 462
             :||        ||     |...|......|...|:.||.....|.|...|.:..| |.|....:
  Rat   376 NISNSQILDKLKPPGLSPFPAASSTQQNDNASPPATTAAWDLKPSAPQPSVLSHLD-FKSQPEPS 439

  Fly   463 ATLVHQAQKQQQLQQQTTPIKPSATLSVEQSQYFNSLASQGVSPG--SVPVQ-----SAPAGYAQ 520
            ..|...:|:||| |.|...:.|                     ||  |.|.|     |||
  Rat   440 PVLSQLSQRQQQ-QNQAVSVPP---------------------PGLESFPSQTKHRESAP----- 477

  Fly   521 NPVAAYSQTSTSVGVSQYPNTYANVFASGTAAGAGTAEQSQQQPQ-IRRARVKLPPPSKIPASAV 584
                           ...|:|...:....|.|........|.||: |:..:.::||.||:|.|||
  Rat   478 ---------------GDGPSTVNRLLQLPTMAVENIVSAHQPQPKHIKLPKRRIPPASKVPVSAV 527

  Fly   585 EMPGDNALNNIGYLDVQFGALDFGTDDGFEPLPEKVGSGFSIDGQQQQQQPDDYQSKSQQQQQVT 649
            ||||.   .:|..|:||||||:||:    ||...:.||               ..|.|:...|:.
  Rat   528 EMPGS---ADITGLNVQFGALEFGS----EPSLSEFGS---------------TASASENSSQLP 570

  Fly   650 LAAGLQSSQISDALNAAGYTSRSTSQQQQGVSSAVNATIDQLTKSDPYGQTGGSGNAYQNAYQSS 714
            ::  |....:|:.|||: :...|..|.....:|.:  |...||                    ||
  Rat   571 IS--LYPKSLSEPLNAS-FPMTSAVQNPTYTTSVI--TSSTLT--------------------SS 610

  Fly   715 GASKTASGFPTTAPGGYSSSTYANVQSSVANSYQQQGYGSYQPSSYQQQAGSGAQSGTGAVSGGG 779
            ..|.|:   |.|....|..|   :|.:.:|               ||..| |.|.:..|:|:.|.
  Rat   611 SVSSTS---PVTTCSSYDQS---SVHTRIA---------------YQSPA-SPADAAPGSVANGH 653

  Fly   780 GTATQNIPVGGSSSQNSTSVSTSSGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNV 844
                     ||..||:  :|.|:|.|.:                ..:...|...|||...|.|:.
  Rat   654 ---------GGGRSQH--TVDTTSSVPA----------------PKKTDPSALPSVSSLPSPSSC 691

  Fly   845 TAGVASGNVAGVGGGVSQSGVSSGVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAV 909
            ||.:...         ||...:.....||..:||....::::.||..|..::|.|..:|.|..
  Rat   692 TALLPPS---------SQHTATLPALTPGELSSSPLSQLSSSLSSHQSSLSSTHATRSTSTPH-- 745

  Fly   910 LASLTNKNTSSSNSSGSGGSAATTTGNASGQGAGASTGGVG--SSSGAGGAGSGGGSG------- 965
                |:.:..|:.|| :..||||:..:|...|. |..|.:.  ||...||......|.
  Rat   746 ----THASVESTPSS-AAFSAATSAPSAPSSGV-ALPGSMSTVSSLCLGGTTVSAPSSSTRATAL 804

  Fly   966 --SGLVPTNIQ------MVSQYIQTG----LPYYQQPVYSYEELQMMQQRVPHVQGYYDLNYPPA 1018
              ||..|.|:.      :.:||: .|    ||.|  |:|.|:||||:|.|:|  ..||.:.:...
  Rat   805 VTSGKAPPNLPQGVPPLLHNQYL-VGPGGLLPAY--PIYGYDELQMLQSRLP--MDYYGIPFAAP 864

  Fly  1019 SLGAGRD-NLGSVTYSAMNDGRFARTDNNSSPVGNVSSTMSQQAGSSA------PMLN--VPYAY 1074
            :..|.|| ||.:..||. :..:|.|.| ::||....:...:||:.|..      |.||  :|..|
  Rat   865 TALASRDGNLANNPYSG-DVTKFGRGD-SASPAPPTTPAQAQQSQSQTHHTAQQPFLNPALPPGY 927

  Fly  1075 FYGG----NVMPGSFQYGTPAIYPQIPAANTASGQQFPKP----SYSAGYG----STSYDTLSQT 1127
            .|.|    ..:||:||||.....|  |.:....|.....|    ..::|||    |..||.|:|.
  Rat   928 SYTGLPYYTGVPGAFQYGPTMFVP--PTSAKQHGVTLSTPPTPFQQASGYGQHAYSAGYDDLTQG 990

  Fly  1128 TQ--DYSKGGYSSSVNQQSK------TQTVSNQSQAGTG-SDLTSSMYGKGHVALNKVNSYEKQS 1183
            |.  ||:||||..|....:|      ::.||..|  ||| .|:|.|:|       ||..:::||.
  Rat   991 TAAGDYTKGGYGGSSQAPNKSAGSGPSKGVSVSS--GTGLPDMTGSVY-------NKTQTFDKQG 1046

  Fly  1184 FHSGTPPPFNMPNT---------QTAGGTSAQPYGMYLPMPAAGHHNMIHQPIHQDSNS-AGQRQ 1238
            ||:||||||::|:.         ..|.|.:..|:...:|.....|..::|..:.||:.| :|||.
  Rat  1047 FHTGTPPPFSLPSALGSTGPLAPGAAPGYAPAPFLHIMPAHQQPHSQLLHHHLPQDAPSGSGQRS 1111

  Fly  1239 QSTS-QSKS-AGKQGYSPS-YW 1257
            |.:| |.|| |.|..|..| ||
  Rat  1112 QPSSLQPKSQASKPTYGNSPYW 1133

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lig	NP_001260795.1	UBA_UBP2_like	85..122	CDD:270463	9/36 (25%)
		CAF-1_p60_C	498..589	CDD:292150	27/98 (28%)
		DUF3697	575..607	CDD:289261	19/31 (61%)
Ubap2	XP_038965766.1	UBA_UBP2_like	59..96	CDD:270463	13/60 (22%)
		DUF3697	518..547	CDD:372135	19/31 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353681
Domainoid	1	1.000	134	1.000	Domainoid score	I4881
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4308
OMA	1	1.010	-	-		QHG47464
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003488
OrthoInspector	1	1.000	-	-		otm44487
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16308
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2380
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.090