Protein Alignment lig and lig

DIOPT Version :10

• Sequence 1: NP_001260795.1
• Gene: lig / 35771
• FlyBaseID: FBgn0020279
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: XP_061504039.1
• Gene: lig / 1278410
• VectorBaseID: AGAMI1_010795
• Length: 1456
• Species: Anopheles gambiae
• Alignment Length: 1614
• Identity: 611/1614 - (37%)
• Similarity: 761/1614 - (47%)
• Gaps: 511/1614 - (31%)

  Fly     1 MSTQTRSGGGGGGGHARNQKK-----------------------------SNASNS--------- 27
            |||||||||||||| .||:.|                             :|||.:
Mosquito     1 MSTQTRSGGGGGGG-GRNKSKAKHHENKENLAKEDGQNQSQQYPKGGSGPNNASGNDGSAATTGS 64

  Fly    28 -GGG---------GTGHHDGVSHAA---------------------AAG----KKGGQ------- 50
             |||         |:|.|.|..:||                     |||    |.||.
Mosquito    65 VGGGRGGDHQKQKGSGGHKGTDNAAPKVVDVKEKQQREAGGGSGGGAAGGNNEKSGGSTGAASGA 129

  Fly    51 ---DASKTDKPEKA-QPKATTEQLRIAQITN--STTEDPQINEKVLLLLTMTQRSEEEVCCALNE 109
               .||.|....|| ||  |.||:||||||:  |..:||:|.||:..|:..||||||||||||.|
Mosquito   130 GAGGASATHTVVKAKQP--TAEQIRIAQITDIKSGMDDPKIQEKIQSLMETTQRSEEEVCCALQE 192

  Fly   110 CDYDLEAAANFLIEELPQGAFAKYEKKRKNKA-ANNTADGAAGDGDWAD-------------GNG 160
            ||.||:.|..||:|.||.||||...||:|:|: |....||..| |||..             |..
Mosquito   193 CDSDLDRAVIFLLETLPVGAFATTSKKKKSKSQAAAQKDGEDG-GDWETTGPTTVGGASVQLGGI 256

  Fly   161 NADRREKSRNRSSNRGGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAG--QDRGDDRANDN 223
            |.|.:|:.|     |||.||.|.              ||| |..|..|..||  :|.|.||..|.
Mosquito   257 NVDLKEQQR-----RGGNRGGSG--------------NQR-SGGPGRGGRAGGYRDGGGDRDRDR 301

  Fly   224 YRGQRNGGGRSGPGGGGRGGGFVSRSGRGGGRMGGRTGGPRGDRGSGGPG-GAYGS--GRGGN-- 283
               .|||..:     ||.|||:.:|:|..||||.|...||      |||| |.|||  ||||.
Mosquito   302 ---DRNGYDK-----GGEGGGYRNRAGGDGGRMRGGRDGP------GGPGRGNYGSRGGRGGGPR 352

  Fly   284 -----------------ANEDHHEVELWDN-TIAQNAE----KQQQAHDDAWGDWNNEEYEGSLK 326
                             .|.||.|::.||. |...||.    :...|..|.||||:||||.|:|.
Mosquito   353 LGTRGPGSRDQNRGSRMMNNDHQEIDSWDPVTTPANANDLKPEDCTAFTDTWGDWDNEEYTGTLA 417

  Fly   327 DSKVFTTSNLATQSAANVVSGTGA--------SVTAVPAAAG--TEISAPPGLEHQLVQQGSHLE 381
            |:|.:..:..:|.:.:   :|.||        :.|.||.||.  ||::||||||.|
Mosquito   418 DTKGYAGAVASTTAPS---AGAGAQQQQSQQSTQTGVPPAASNVTELAAPPGLEQQ--------- 470

  Fly   382 ESSSSGPAAVTPPATLSGSATTPLLQYSAAVSNPPPQ-----LQSQGTQSGAGTGASAAAGGGAG 441
                                          |.||||.     :|...|...:.|..:|.|.|||.
Mosquito   471 ------------------------------VLNPPPPKDTELVQQYSTTVVSSTATAAVAAGGAT 505

  Fly   442 STPSSFVSASPDTFSSAASAAATLVHQAQKQQQLQQQTTPIKPSATLSVEQSQYFNSLASQGVSP 506
            .. :|.|....|..:...:|.....|..|....     .|:..|::||.||||||::|:||  :.
Mosquito   506 GV-ASVVPQYSDLHAGTPNATTAAQHLRQALDM-----PPMNTSSSLSAEQSQYFSTLSSQ--NS 562

  Fly   507 GSVPVQSAPAGYAQNPVAAY--SQTSTSV-------------GVSQYPNTY----ANVFASGTAA 552
            ...|..|| .|:.|.|.|..  ||..|:|             ...|||..:    ::..|:..||
Mosquito   563 NLQPTPSA-VGFQQQPPAGVVASQPPTTVVPAVQQQQQPPQPNSVQYPTAFVGATSDATAAAAAA 626

  Fly   553 GAGT--AEQSQQQPQIRRARVKLPPPSKIPASAVEMPGDNALNNIGYLDVQFGALDFGTDDGFEP 615
            ||.|  |..:.|||.:||.|.::|||||||:||||||||| :|||||||||||.||||.||.|:.
Mosquito   627 GAPTSYAAAATQQPPVRRQRARVPPPSKIPSSAVEMPGDN-MNNIGYLDVQFGGLDFGADDSFDA 690

  Fly   616 -LPEKVGSGFSIDG----------------------------------QQQQQ-----------Q 634
             :.:|..|.....|                                  |||||           |
Mosquito   691 VVSDKFNSTTGTAGSSVMDSTPSTVQTSVVSQATQAVGQPQASQTQTVQQQQQGAQVPPATVGVQ 755

  Fly   635 PDDYQSKSQQQQQVTL------------------------------------------AAGLQSS 657
            |...||:.|||||..:                                          |.||.||
Mosquito   756 PPAAQSQLQQQQQQVVSQAPQQTVQPDVNDYQSKVGGGVVAGSVVPNNLQPKSSNLPGAPGLASS 820

  Fly   658 QI-------------SDAL-------NAAGYTSRSTSQQQQGVSSAVN--ATIDQLTKSDPYGQT 700
            ||             :|.|       ||:|..|.|.|   .||:|..|  |.:|||||||||||:
Mosquito   821 QIMPGQGTTEALSSQNDGLANSYSRTNASGSVSTSVS---AGVNSMSNAAAALDQLTKSDPYGQS 882

  Fly   701 GGSGNA----YQNA-YQSSGASKTASGFPTTAPGGYSSSTYANVQSSVA--------NSYQQQGY 752
            ..:..|    |||| |.|:.|:||||..||.||.||::.:|:|.|.:.|        :||.|...
Mosquito   883 ASTNTALTGGYQNAPYSSTQANKTASYPPTGAPQGYNNMSYSNNQVTNAYPPSTNNYSSYNQGNV 947

  Fly   753 GSYQPSSYQQQAGSGAQSGTGAVSGG----------------------GGTATQNIPVGGSSS-- 793
            .:|||.|..........:.||...||                      ||..:...||..:||
Mosquito   948 NAYQPPSSSVTNNVVPNNNTGNSVGGVSNQSNLPVNNNAVNSSSNNNAGGYLSSQYPVSQTSSAF 1012

  Fly   794 ------QNST-SVSTSSGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNVTAGVASG 851
                  |||: :|..::|::||:|.:|:....|||.|:|    .:::.:..:..||.....|||.
Mosquito  1013 PSQQNYQNSSQNVYGNTGLNSNTGYSGSTNTTSGQYGSN----FSSSKLKDTPVVSTPFESVASS 1073

  Fly   852 NVAGVGGGVSQSGVSSGVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAVLASLTNK 916
            .|                     |.||.. |.|||.:|:||:..::|..|.:..|     .|.||
Mosquito  1074 TV---------------------SNSSTN-NSNNNVTSSSSLPISSVVSTTSKYT-----YLANK 1111

  Fly   917 NTSSSN---------------SSGSGGSAATTTGNASGQGAGASTGGVGSSSGAGGAGSGGGSGS 966
            ...:.|               ...:..|::||:|.:
Mosquito  1112 TVETRNLLLHNVFVLLLLCIILYFAAKSSSTTSGTS----------------------------- 1147

  Fly   967 GLVPTNIQMVSQYIQT-GLPYYQQ-PVYSYEELQMMQQRVPHVQGYYDLNY-PPASLGAG--RD- 1025
              |.||:.||:.|||. |||:||| .|||||:||:||||:|||.|:||:|| .|.||||.  ||
Mosquito  1148 --VVTNLPMVNPYIQAPGLPFYQQAAVYSYEDLQLMQQRMPHVPGFYDINYQTPTSLGAAGVRDA 1210

  Fly  1026 NLGSVTYSAMNDGRFARTDNNSSPVGNVSSTMSQQAGSSAPMLNVPYAYFYGGNVMPGS-FQYGT 1089
            |||||.||.|:||||.|||||||||.||.|::|||.||..||||:|||||||||:||.| |||||
Mosquito  1211 NLGSVAYSTMSDGRFTRTDNNSSPVSNVPSSLSQQTGSGGPMLNLPYAYFYGGNMMPASGFQYGT 1275

  Fly  1090 PAIYP-QIPAANTASGQQFPKPSY-SAGYGS-TSYDTLSQTTQDYSKGGYSSSV--NQQSKTQTV 1149
            | :|| |:|.....||.||.||:| :.|||| |.||||.|:.|||:|..|.:|:  .||||.|||
Mosquito  1276 P-VYPQQMPTNAATSGGQFQKPAYNTGGYGSATGYDTLGQSGQDYNKNAYQASIVGQQQSKGQTV 1339

  Fly  1150 SN-QSQAGTGSDLTSSMYGKGHVALNKVNSYEKQSFHSGTPPPFNMPNTQTAGGTSAQPYGM--- 1210
            :| ||.:|:|||:..|||||.|||:|||| |:|||||||||||:|:..|||||.|||||||.
Mosquito  1340 ANQQSGSGSGSDMAPSMYGKNHVAINKVN-YDKQSFHSGTPPPYNIAGTQTAGTTSAQPYGQHLA 1403

  Fly  1211 YLPMPAAGHHNM-IHQPIHQDSNSAGQRQQSTSQSKSAGK-QGYSPS-YWAGQN 1261
            |:|..|. |||: :||.:||||||:|||.|:.:|.|:|.| ||||.| ||.|.|
Mosquito  1404 YIPTMAT-HHNINMHQNMHQDSNSSGQRPQNNNQGKTASKQQGYSASTYWTGPN 1456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lig	NP_001260795.1	PRK12678	16..>229	CDD:237171	106/314 (34%)
		UBA_UBP2_like	85..122	CDD:270463	23/36 (64%)
		DUF3697	575..607	CDD:372135	27/31 (87%)
lig	XP_061504039.1	None