Protein Alignment lig and ubap2

DIOPT Version :10

• Sequence 1: NP_001260795.1
• Gene: lig / 35771
• FlyBaseID: FBgn0020279
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: XP_004910371.2
• Gene: ubap2 / 100379870
• XenbaseID: XB-GENE-5921250
• Length: 1131
• Species: Xenopus tropicalis
• Alignment Length: 1363
• Identity: 367/1363 - (26%)
• Similarity: 534/1363 - (39%)
• Gaps: 409/1363 - (30%)

  Fly    56 DKPEKAQP--------KATTEQLRIAQITNSTTEDPQINEKVLLLLTMTQRSEEEVCCALNECDY 112
            :||:.:.|        :||.||:|:||:... ..|.:..:||..|:.:|.::::|...||::|:.
 Frog    15 EKPQISAPQTQTQKQVQATAEQIRLAQMIYD-KNDAEFEDKVKQLMEVTGKNQDECIVALHDCNG 78

  Fly   113 DLEAAANFLIEELPQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNG-----------NADRRE 166
            |:..|.|.|:|                        |.:....|....|           |.:.||
 Frog    79 DVNRAINILLE------------------------GNSDTTSWETVGGKKKSIGKESSENKENRE 119

  Fly   167 KSRNRSSNRGGTRGSSDSR---GWRGRETRENERNQRESREPWSGQNAGQDRG-DDRANDNYRGQ 227
            :..:|..:||  ||||..|   |.||||.|..|.              |.|.| .||.:|  ||:
 Frog   120 RRGDREMSRG--RGSSSRRGRGGSRGREFRAEEN--------------GVDIGPGDRPSD--RGR 166

  Fly   228 RNGGGRSGPGGGGRGGGFVSRSGRGGGRMGGRTGGPRGDRGSGGPGGAYGSGRGGNANEDHHEVE 292
            |   || |.|.||||      .|||.||...:..|.........|          .||:...:.:
 Frog   167 R---GR-GRGFGGRG------RGRGSGRFSAQGMGTFNPADYTEP----------TANDGVAKTD 211

  Fly   293 LWDNTIAQNAEKQQQAHDD---------------AW----GDWNNEEYEGSLKDSKVFTTSNLAT 338
            :|        |..|...||               ||    .:|..|::...|.::||||.|::.|
 Frog   212 VW--------ETGQSDCDDGTEISGSPFLPPLKGAWRSSLEEWTTEDWNEDLSETKVFTASSVPT 268

  Fly   339 QSAANVVSGTGASVTAV--PAAAGTEISAPPGLEHQLVQQGSHLEESSSSGPAAVTPPATLSGSA 401
            ::  ::..|....:.|:  ...:|||..:......|....|..|..::|...:.:||.||.:.:|
 Frog   269 EN--HITPGQSIDLVALLQKQPSGTETDSVTFEASQQQNYGQALVFTNSQHSSQITPVATTTSNA 331

  Fly   402 TTPLLQY-----------------SAAVSNPP-----PQLQSQG---------TQSGAGTGASAA 435
            ..   .|                 |:.::|.|     .||:|.|         .||..||.||.:
 Frog   332 VN---SYSPQSLSSVLGSGFGELGSSKLTNSPGSQILEQLKSPGLGQFTNQTPQQSSTGTAASTS 393

  Fly   436 -----AGGGAGSTPSSFVSASPDTFSSAASAAATLVHQAQKQQQLQQQTTPIKPSATLSVEQSQY 495
                 .|      |.|.|....| |.|....:..|....|:    |.|..|:.|..
 Frog   394 WDIKPTG------PQSSVLGQFD-FKSQPEPSPVLSQLTQR----QHQAVPVPPPG--------- 438

  Fly   496 FNSLASQGVSPGSVPVQSAPAGYAQNPVAAYSQTSTSVGVSQYPNTYANVFASGTAAGAGTAEQS 560
            ..|..||.....:.||.|:.|......::..|..:.::                      :|:|:
 Frog   439 LESFTSQVKLRETSPVDSSSAVSKMLQLSNLSLDTQTI----------------------SAQQT 481

  Fly   561 QQQPQIRRARVKLPPPSK-----IPASAVEMPGDNALNNIGYLDVQFGALDFGTDDGFEPLPEKV 620
            |||.|::..:.::||.||     ||||||||||.   .::..|:||||||:||:    ||...:.
 Frog   482 QQQKQLKPQKRRIPPTSKVGIQEIPASAVEMPGS---ADVSGLNVQFGALEFGS----EPSLAEF 539

  Fly   621 GSGFSIDGQQQQQQPDDYQSKSQQQQQVTLAAGLQSS-QISDALNAAGYT-------SRSTSQQQ 677
            ||..|.|  ...|.|.:..||       |::..|.:. .||.|:....||       |.|:|.|.
 Frog   540 GSNSSPD--TATQTPSNLYSK-------TISDSLNTPLPISSAVQEPSYTPTVIATSSLSSSSQS 595

  Fly   678 QGVSSAVNATIDQLTKSDPYGQTGGSGNAYQNAYQSSGASKTASGFPTTAPGGYSSSTYANVQSS 742
               :|.|.||   .:.|..|.||......   |||||  ...|...|.|  .|::........||
 Frog   596 ---TSPVTAT---SSSSSSYDQTSVHSRV---AYQSS--MPPAEVVPVT--NGHNGIRAQTTLSS 647

  Fly   743 VANSYQQQGYGSYQPSSYQQQAGSGAQSGTGAVSGGGGTATQNIPVGGSSSQNSTSVSTS----- 802
            ..         |.||  .:.::...:.|..|::.....|.:..:|   |:.|:|::||.|
 Frog   648 TP---------SVQP--VKPESSPPSLSSVGSLPSTVPTTSSLLP---SAPQHSSAVSLSSLPQP 698

  Fly   803 SGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNVTAGVASGNVAGVGGGVSQSGVSS 867
            |.:||...|..| ..:||          :.||:..:|.:|:
 Frog   699 SDLSSTPLSQLN-STLSG----------HQNSLPAASVLSS------------------------ 728

  Fly   868 GVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAVLASLTNKNTSSSNSSGSGGSAAT 932
                   :||....:|.:..|...|...:|.:.:||.||:||::..:..|  |.|:.|      .
 Frog   729 -------TASHSHTSVESTVSLQPSATFSTASTSATSTTSAVVSMASTMN--SINTLG------L 778

  Fly   933 TTGNASGQGAGASTGGVGSSSGAGGAGSGGGSGSGLVPTNIQ------MVSQYIQTG----LPYY 987
            |..:.|...|...|..:.:              ||..|.|:.      :.:||| .|    ||.|
 Frog   779 TAPSISMPAATTRTAPLVT--------------SGKAPPNLPQGVPPLLHNQYI-VGPGGLLPAY 828

  Fly   988 QQPVYSYEELQMMQQRVPHVQGYYDLNYP-PASLGAGRD-NLGSVTYSAMNDGRFARTDNNS-SP 1049
            .| :|.|::|||:|.|:|  ..||.:.:| ||:| .||| .|.|..||. :..:|.|.|:.| :|
 Frog   829 PQ-IYGYDDLQMLQSRLP--MDYYGITFPAPATL-TGRDGGLASNPYSG-DVAKFGRADSASPAP 888

  Fly  1050 VGNVSSTMSQQA----GSSAPMLN--VPYAYFYGG-------NVMPGSFQYGTPAIYPQIPAANT 1101
            ...::.....|.    .:..|.||  :|..|.|.|       ..:|.:||||.....|  ||:..
 Frog   889 ATTLAQPQQNQTQTHHTAQQPFLNPTLPPGYSYTGLPYYAGVPGVPSAFQYGPTMFVP--PASAK 951

  Fly  1102 ASGQQFPKPS----YSAGYGSTS----YDTLSQTT--QDYSKGGYSSSVNQQSKTQTVSNQSQAG 1156
            ..|......|    .:.|||..|    ||.|:|.|  .||||||||.|...|||:        ||
 Frog   952 QHGVNLSTASTPFQQAGGYGQHSYGAGYDDLTQGTAAADYSKGGYSGSSQAQSKS--------AG 1008

  Fly  1157 TG--------------SDLTSSMYGKGHVALNKVNSYEKQSFHSGTPPPFNMP---------NTQ 1198
            ||              .|::.|:|       ||..:::||.||:.|||||::|         |..
 Frog  1009 TGPGKGVSVSSSNTGVPDISGSVY-------NKTQTFDKQGFHAATPPPFSLPSALGSTGPLNPG 1066

  Fly  1199 TAGGTSAQPYGMYLPMPAAGHHNMIHQPIHQD--SNSAGQRQQSTSQSKS-AGKQGYSPS-YW 1257
            .|.|.:..|:...||.....|..::|..:.||  ..||.:.|.:..|.|| |.|..|:.| ||
 Frog  1067 AAAGYAPAPFLHILPAHQQPHSQLLHHHLQQDGQGGSAQRTQPNAMQQKSQANKTAYASSPYW 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lig	NP_001260795.1	PRK12678	16..>229	CDD:237171	53/195 (27%)
		UBA_UBP2_like	85..122	CDD:270463	11/36 (31%)
		DUF3697	575..607	CDD:372135	20/36 (56%)
ubap2	XP_004910371.2	UBA_UBP2_like	51..88	CDD:270463	11/36 (31%)
		DUF3697	496..530	CDD:372135	20/36 (56%)