Protein Alignment CG12769 and Zfp423

DIOPT Version :10

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: XP_063134398.1
• Gene: Zfp423 / 94188
• RGDID: 621664
• Length: 1316
• Species: Rattus norvegicus
• Alignment Length: 855
• Identity: 156/855 - (18%)
• Similarity: 262/855 - (30%)
• Gaps: 280/855 - (32%)

  Fly    47 RSLKDAASSASESELQEPRSPTPTPTNLSTGPHSPPMTFRCERC-DSFETSSRASLLLHVVQCLA 110
            |:|:|..|..|:.|..|........:           .:.|:.| ..||  |.|.|..|......
  Rat    48 RALEDRNSVTSQEERNEDDEDVEDES-----------IYTCDHCQQDFE--SLADLTDHRAHRCP 99

  Fly   111 GQAAAAAAAAAASARLKSEDLQEPENM-------SLGHMEGGKG---DGQTGNGSSSSASSSPAG 165
            |........:..::...|:|:..|..|       .||..|||.|   ..|..:.|....|.....
  Rat   100 GDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRH 164

  Fly   166 NSGGGGGGNSSSRKVFECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTT 230
            ..      ..|.:..|:|..|:..|.:..:..||...|||.|.|.|..|:..|.|.|||..|..|
  Rat   165 EQ------IHSDKLPFKCTFCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKT 223

  Fly   231 HTKTLPYHCPICNRGFQRQIAMRAHFQNEHVGQHDLVKT-------------------------- 269
            |:.:.|:.|.:|.|||....::::|.|.....:..|.|:
  Rat   224 HSSSKPFKCSVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEK 288

  Fly   270 --------------------------------------------CPLCSYRAGSMKSLRIHFFNR 290
                                                        ||:|..:..|::.:..|..:.
  Rat   289 HVLTLHPQLSEKADLQCIHCPEVFVDESTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 353

  Fly   291 HGIDLDN----PGPGGTSSLLLALESQASAAAAAAAASYVPPGLSP----VPVQSQSQQQQQQQV 347
            ...|..|    |.|     :|.::.|.:||...::|:  |..|.:|    .|::.|.:.:
  Rat   354 RQPDSSNHSVSPDP-----VLGSVASMSSATPDSSAS--VERGSTPDSTLKPLRGQKKMR----- 406

  Fly   348 APPASDSGESMRSLENATP-------------PMHFLTPHVE----------------------- 376
                 |.|:|...:..:.|             .:|..|.|.:
  Rat   407 -----DDGQSWSKVVYSCPYCSKRDFTSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNE 466

  Fly   377 -ISTLGES--------GNTELFNLICVWRESALQGNNNNNNN---NNCATNNNNNINGASNNCNS 429
             :..|.:|        ||...|:  |.:........|:...:   ::|..|.|......:..||.
  Rat   467 HVRKLHKSHAYPVMQFGNISAFH--CNYCPEMFADINSLQEHIRVSHCGPNANPPDGNNAFFCNQ 529

  Fly   430 ISNG------------NAESNGDKVKDRALIMQSPVELPMD----------CNTKATPITSSTTA 472
            .|.|            .|..:....|     ::|||..|..          |..  :||..|..
  Rat   530 CSMGFLTESSLTEHIQQAHCSVGSTK-----LESPVIQPTQSFMEVYSCPYCTN--SPIFGSIL- 586

  Fly   473 SSLSGGLKSHHQH-PHHHHHHHHHHENHITPSISLIPIKQEPMSEDMDKKDLMNGSDPSSDTEQA 536
             .|:..:|.:|:: |..|.......::.::..:.:...|::.:|...:  .:.||..|.:..:..
  Rat   587 -KLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSGSAN--SISNGEYPCNQCDLK 648

  Fly   537 SNNNNSSSNNNRITSLIKVSPLKSLLREDLKRRICAKANNRITRNATPLESNNNNSVLSNSLSNG 601
            .:|..|...:           ||..|...|:::.|.:...         :.::..|:|.:...:.
  Rat   649 FSNFESFQTH-----------LKLHLELLLRKQACPQCKE---------DFDSQESLLQHLTVHY 693

  Fly   602 SGRGSPGVNGGSGGGGGGGPPTPAT----PSATNGASSTP-------------ICNGTITSTGQD 649
            .                    |.:|    .|.....||..             :.:.|:.....|
  Rat   694 M--------------------TTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFD 738

  Fly   650 GDLLI---------NRKLILTCHFCGIEFPDETLYFLH-KGCHCESNP---WRCNICGEQLNNVY 701
            ..:.|         |.|.:..|..|..:|..|....:| |..|. .||   .:|..|||..:...
  Rat   739 SKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHL-GNPAKAHKCIFCGETFSTEV 802

  Fly   702 EFNSHLLSKS 711
            |...|:.:.|
  Rat   803 ELQCHITTHS 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	5/19 (26%)
		zf-H2C2_2	195..218	CDD:463886	9/22 (41%)
		C2H2 Zn finger	211..231	CDD:275368	8/19 (42%)
		C2H2 Zn finger	239..255	CDD:275368	5/15 (33%)
		C2H2 Zn finger	662..689	CDD:275371	9/30 (30%)
		C2H2 Zn finger	690..712	CDD:275371	7/22 (32%)
Zfp423	XP_063134398.1	None