DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12769 and Ctcf

DIOPT Version :10

Sequence 1:NP_001286181.1 Gene:CG12769 / 35770 FlyBaseID:FBgn0033252 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_006255598.1 Gene:Ctcf / 83726 RGDID:621344 Length:738 Species:Rattus norvegicus


Alignment Length:207 Identity:48/207 - (23%)
Similarity:82/207 - (39%) Gaps:45/207 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 RKVFECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTTHTKTLPYHCPIC 242
            :|.|:|::|:......:|:.||...||..:|::|.:|.:.|.....|..|..|||.|.|:.||.|
  Rat   263 KKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDC 327

  Fly   243 NRGFQRQIAMRAHFQNEHVGQHDLVKTCPLCSYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLL 307
            :..|.....:..|.:.:|.  |:....|.:|.|.:..:..|:.|..:..|   :.|         
  Rat   328 DMAFVTSGELVRHRRYKHT--HEKPFKCSMCDYASVEVSKLKRHIRSHTG---ERP--------- 378

  Fly   308 LALESQASAAAAAAAASYVPPGLSPVPVQSQSQQQQQQQVAPPASDSGES--------MRSLENA 364
                .|.|..:.|:..:|              :.::..:     :.|||.        .|..::.
  Rat   379 ----FQCSLCSYASRDTY--------------KLKRHMR-----THSGEKPYECYICHARFTQSG 420

  Fly   365 TPPMHFLTPHVE 376
            |..||.|..|.|
  Rat   421 TMKMHILQKHTE 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12769NP_001286181.1 C2H2 Zn finger 183..203 CDD:275368 5/19 (26%)
zf-H2C2_2 195..218 CDD:463886 8/22 (36%)
C2H2 Zn finger 211..231 CDD:275368 5/19 (26%)
C2H2 Zn finger 239..255 CDD:275368 4/15 (27%)
C2H2 Zn finger 662..689 CDD:275371
C2H2 Zn finger 690..712 CDD:275371
CtcfXP_006255598.1 zf-H2C2_5 266..289 CDD:404746 6/22 (27%)
C2H2 Zn finger 268..288 CDD:275368 5/19 (26%)
zf-H2C2_2 280..305 CDD:463886 9/24 (38%)
C2H2 Zn finger 296..316 CDD:275368 5/19 (26%)
zf-H2C2_2 309..333 CDD:463886 11/23 (48%)
C2H2 Zn finger 324..347 CDD:275368 6/24 (25%)
zf-H2C2_5 351..375 CDD:404746 5/23 (22%)
C2H2 Zn finger 353..373 CDD:275368 5/19 (26%)
COG5048 <366..500 CDD:227381 18/102 (18%)
C2H2 Zn finger 381..401 CDD:275368 3/38 (8%)
C2H2 Zn finger 409..426 CDD:275368 3/16 (19%)
C2H2 Zn finger 439..457 CDD:275368
C2H2 Zn finger 469..489 CDD:275368
C2H2 Zn finger 497..517 CDD:275368
zf-H2C2_2 509..534 CDD:463886
C2H2 Zn finger 525..546 CDD:275368
C2H2 Zn finger 557..573 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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