Protein Alignment CG12769 and Ikzf5

DIOPT Version :10

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_780324.2
• Gene: Ikzf5 / 67143
• MGIID: 1914393
• Length: 419
• Species: Mus musculus
• Alignment Length: 602
• Identity: 122/602 - (20%)
• Similarity: 176/602 - (29%)
• Gaps: 237/602 - (39%)

  Fly   136 NMSLGHMEGGKGDGQTGNGSSSSASSSPAGNSGGGGGGNSSSRKV------------FE------ 182
            ||..|.:.|.| :.:|..|         ||..|...|.:..|.:|            ||
Mouse    27 NMISGSVSGDK-EAETLQG---------AGTDGDQNGLDHPSVEVSLDENSGMLVDGFERTFDGK 81

  Fly   183 --CDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTTHTKTLPYHCPICNRG 245
              |..||......|.:..|...|||.||:.|.:|......:.||..|..:||...||
Mouse    82 LKCRYCNYASKGTARLIEHIRIHTGEKPHRCHLCPFASAYERHLEAHMRSHTGEKPY-------- 138

  Fly   246 FQRQIAMRAHFQNEHVGQHDLVKTCPLCSYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLLLAL 310
                                   .|.|||:|.....:|..|...:|.:   .|..|..|||
Mouse   139 -----------------------KCELCSFRCSDRSNLSHHRRRKHKM---VPIKGTRSSL---- 173

  Fly   311 ESQASAAAAAAAASYVPPGLSPVPVQSQSQQQQQQQVAPPASDSGESMRSLENATPPMHFLTPHV 375
                                        |.::....:....|:.|.|.|:|.|.:||
Mouse   174 ----------------------------SSKKMWGVLQKKTSNLGYSRRALINLSPP-------- 202

  Fly   376 EISTLGESGNTELFNLICVWRESALQGNNNNNNNNNCATNNNNNINGASNNCNSISNGNAESNGD 440
                                               :......:.:|..::...:|...:.|:..
Mouse   203 -----------------------------------SMVVQKPDYLNDFTHEIPNIQTDSYEAMA- 231

  Fly   441 KVKDRALIMQSPVELPMDCNTKATPITS-STTASSLSGGLKSHHQHPHHHHHHHHHHENHITPSI 504
            |......:.:.|.||.:|     .|:.. ||.|..||
Mouse   232 KTTPTGGLPRDPQELMVD-----NPLNQLSTLAGQLS---------------------------- 263

  Fly   505 SLIPIKQEPMSEDM----DKKDLMNGSDPSSDTEQASNNNNSSSNNNRITSLIKVSPLKSLLRED 565
            ||.|..|.|.|.|:    |:|..|. ..||:..               :.|.:..|
Mouse   264 SLPPENQNPASPDVDACPDEKPFMI-QQPSAQA---------------VVSAVSAS--------- 303

  Fly   566 LKRRICAKANNRITRNATPLESNNNNSVLSNSLSNGSGRGSPGVNGGSGGGGGGGPPTPATPSAT 630
                 ..::::..:....|..|..|.|.::...|..|...|                   |||..
Mouse   304 -----IPQSSSPTSPEPRPSHSQRNYSPVAGPSSEPSAHTS-------------------TPSIG 344

  Fly   631 NGASSTPICNGTITSTGQDGDLLINRKLILTCHFCGIEFPDETLYFLHKGCHCESNPWRCNICGE 695
            |...|||    ..|...||..||.:      |..|.:.|.|..||.:|.|||...:|::||:||.
Mouse   345 NSQPSTP----APTLPVQDPQLLHH------CQHCDVYFADNVLYTVHMGCHGYDSPFQCNVCGC 399

  Fly   696 QLNNVYEFNSHLLSKSH 712
            :..:.|:|..|.....|
Mouse   400 KCKDKYDFACHFARGQH 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	5/19 (26%)
		zf-H2C2_2	195..218	CDD:463886	8/22 (36%)
		C2H2 Zn finger	211..231	CDD:275368	5/19 (26%)
		C2H2 Zn finger	239..255	CDD:275368	0/15 (0%)
		C2H2 Zn finger	662..689	CDD:275371	11/26 (42%)
		C2H2 Zn finger	690..712	CDD:275371	7/21 (33%)
Ikzf5	NP_780324.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..55		7/28 (25%)
		C2H2 Zn finger	84..104	CDD:275368	5/19 (26%)
		zf-H2C2_2	96..121	CDD:463886	8/24 (33%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		zf-H2C2_2	124..148	CDD:463886	12/54 (22%)
		C2H2 Zn finger	140..158	CDD:275368	7/17 (41%)
		KREPA	<256..>373	CDD:483960	40/203 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..284		10/49 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..356		17/95 (18%)
		C2H2 Zn finger	366..393	CDD:275371	11/26 (42%)
		C2H2 Zn finger	394..416	CDD:275371	7/21 (33%)