| Sequence 1: | NP_001286181.1 | Gene: | CG12769 / 35770 | FlyBaseID: | FBgn0033252 | Length: | 713 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001338018.1 | Gene: | IKZF4 / 64375 | HGNCID: | 13179 | Length: | 585 | Species: | Homo sapiens |
| Alignment Length: | 763 | Identity: | 158/763 - (20%) |
|---|---|---|---|
| Similarity: | 248/763 - (32%) | Gaps: | 277/763 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 17 KDPSPTVGGGIIVDMTPTTAALLHHNAMALRSLKDAASSASESELQEPRSPTPTPTNLST--GPH 79
Fly 80 SPP---MTFRCERCDSFETSSRASLLLHVVQCLAGQAAAAAAAAAASARLKSED--------LQE 133
Fly 134 PENMSLGHMEGGKGDGQTGNGSSSSASSSPAGNSGGG---GGGNSSSRKVFECDVCNMKFSNGAN 195
Fly 196 MRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTTHTKTLPYHCPICNRGFQRQIAMRAHFQNEH 260
Fly 261 VGQHDLVK--TCPLCSYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLLLALESQASAAAAAAAA 323
Fly 324 SYVPPG-----LSPVP---VQSQSQQQQQQQVAPPASDSGESMRSLENATPPMHFLTPHVEISTL 380
Fly 381 GESGNTEL-FNLICVWRESALQGNNNNNNNNNCATNNNNNINGASNNCNSISNGNAESN-GDKVK 443
Fly 444 DRALIMQSPVEL-PMDCNTKATPITSS--TTASSLSGGLKSHHQHPHHHHHHHHHHENHITPSIS 505
Fly 506 LIPIKQEPMS--EDM-DKKDLM---------------NGSDPSSDTEQASNNNNSSSNNNRITSL 552
Fly 553 IKV-----------------SPLKSLLREDLKRRICAKANNRITRNATPLESNNNNSVLSNSLSN 600
Fly 601 GSGRGSPGVNGGSGGGGGGGPPTPATPSATNGASSTPICNGTITSTGQDGDLLINRKLILTCHFC 665
Fly 666 GIEFPDETLYFLHKGCHCESNPWRCNICGEQLNNVYEFNSHLLSKSHQ 713 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG12769 | NP_001286181.1 | C2H2 Zn finger | 183..203 | CDD:275368 | 7/19 (37%) |
| zf-H2C2_2 | 195..218 | CDD:290200 | 8/22 (36%) | ||
| C2H2 Zn finger | 211..231 | CDD:275368 | 6/19 (32%) | ||
| C2H2 Zn finger | 239..255 | CDD:275368 | 6/15 (40%) | ||
| C2H2 Zn finger | 662..689 | CDD:275371 | 10/26 (38%) | ||
| C2H2 Zn finger | 690..712 | CDD:275371 | 10/21 (48%) | ||
| IKZF4 | NP_001338018.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..43 | 6/14 (43%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 68..98 | 6/29 (21%) | |||
| C2H2 Zn finger | 161..181 | CDD:275368 | 7/19 (37%) | ||
| zf-H2C2_2 | 174..198 | CDD:404364 | 9/23 (39%) | ||
| C2H2 Zn finger | 189..209 | CDD:275368 | 6/19 (32%) | ||
| zf-H2C2_2 | 201..226 | CDD:404364 | 8/24 (33%) | ||
| SFP1 | <211..271 | CDD:227516 | 14/59 (24%) | ||
| C2H2 Zn finger | 217..237 | CDD:275368 | 7/19 (37%) | ||
| C2H2 Zn finger | 250..271 | CDD:275368 | 4/20 (20%) | ||
| Interaction with FOXP3. /evidence=ECO:0000250|UniProtKB:Q8C208 | 281..585 | 87/448 (19%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 410..489 | 16/112 (14%) | |||
| CTBP-binding motif PEDLA | 425..429 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 152 | 1.000 | Inparanoid score | I4359 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.960 | |||||