Protein Alignment CG12769 and hb

DIOPT Version :10

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_731267.1
• Gene: hb / 41032
• FlyBaseID: FBgn0001180
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 152/731 - (20%)
• Similarity: 236/731 - (32%)
• Gaps: 207/731 - (28%)

  Fly    66 SPTPTPTNLSTGPHSPPMTFRCERCDSFETSSRASLLLHVVQCLAGQAAAAAAAAAASARLKS-- 128
            ||.||||:.||                                    .|..|.|..:|.:|::
  Fly   150 SPQPTPTSAST------------------------------------IAPVAVATGSSEKLQALT 178

  Fly   129 --EDL---QEPENMSLGHMEGGKGDGQTGNGSSS---SASSS--------PAGNSGGGGGGNSSS 177
              .|:   :.|...|..::|..|...|..|.|..   .|.|.        |..||.|       .
  Fly   179 PPMDVTPPKSPAKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHG-------K 236

  Fly   178 RKVFECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFF---RKDHLAEHFTTHTKTLPYHC 239
            .|.::|..|.:......:...|...|  :||.:...|.|..|   .|.||..|...|....|:.|
  Fly   237 MKNYKCKTCGVVAITKVDFWAHTRTH--MKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQC 299

  Fly   240 PICNRGFQRQIAMRAHFQNEHVGQHDLV--KTCPLCSYRAGSMKSLRIH---FFNRHGIDLD--- 296
            ..|:     ...:.....|.|...|..|  ..|..|.|......|.::|   :.::.|:.||
  Fly   300 DKCS-----YTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDG 359

  Fly   297 --------------------NPGP---GGTSS-------LLLALESQASAAAAAAAASYVPPGLS 331
                                |.||   ||:.|       ..:|.:.|.|..|...|.|.:...|.
  Fly   360 TPNPSLVIDVYGTRRGPKSKNGGPIASGGSGSGSRKSNVAAVAPQQQQSQPAQPVATSQLSAALQ 424

  Fly   332 PVP-VQSQSQQQQQQQVAPPASDSGESMRSLENATP----PMHFLTPHVEISTLGESGNTELF-- 389
            ..| ||..|.......|.|..:...:|:.|:|. ||    |.:.|.|..  |.|.::.|...|
  Fly   425 GFPLVQGNSAPPAASPVLPLPASPAKSVASVEQ-TPSLPSPANLLPPLA--SLLQQNRNMAFFPY 486

  Fly   390 -----NLICVWRESA------------LQGNNNNNNNNNCATNNNNNINGASNNCNSISNGNAES 437
                 .::...:::|            ||..|...::|.....::.....:.::...:|.|....
  Fly   487 WNLNLQMLAAQQQAAVLAQLSPRMREQLQQQNQQQSDNEEEEQDDEYERKSVDSAMDLSQGTPVK 551

  Fly   438 NGDKVKDRALIMQSPVELPMDCNTKATPITSSTTASSLSGGLKSHHQHPHHHHHHHHHHENHITP 502
            ..::.:.    .|.|:.:.:....:|||:.||:.||...|                     .:..
  Fly   552 EDEQQQQ----PQQPLAMNLKVEEEATPLMSSSNASRRKG---------------------RVLK 591

  Fly   503 SISLIPIKQEPMSEDMDKKDLMNGSDPSSDTEQASNNNNSSSNNNRITSLIKVSPLKSLLREDLK 567
            ..:|:.::.|.|:.....|      .||:....||                  ||:..  |:.:.
  Fly   592 LDTLLQLRSEAMTSPEQLK------VPSTPMPTAS------------------SPIAG--RKPMP 630

  Fly   568 RRICAKANNRITRNATPLESNNNNSVLSNSLSNG-SGRGSPGVNGGSGGGGGGGPPTPATPSATN 631
            ...|:..::......|......|.|..|.:.|:| |...|...||.|.........|.|..:..:
  Fly   631 EEHCSGTSSADESMETAHVPQANTSASSTASSSGNSSNASSNSNGNSSSNSSSNGTTSAVAAPPS 695

  Fly   632 GASSTPICNGTITSTGQDGDLLINRKLILTCHFCGIEFPDETLYFLHKGCHCESNPWRCNICGEQ 696
            |   ||...|.                |..|.:|.|.|.|..||.:|.|.|...:.::||:|||:
  Fly   696 G---TPAAAGA----------------IYECKYCDIFFKDAVLYTIHMGYHSCDDVFKCNMCGEK 741

  Fly   697 LNNVYEFNSHLLSKSH 712
            .:.......|:...:|
  Fly   742 CDGPVGLFVHMARNAH 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	3/19 (16%)
		zf-H2C2_2	195..218	CDD:463886	6/22 (27%)
		C2H2 Zn finger	211..231	CDD:275368	7/22 (32%)
		C2H2 Zn finger	239..255	CDD:275368	2/15 (13%)
		C2H2 Zn finger	662..689	CDD:275371	10/26 (38%)
		C2H2 Zn finger	690..712	CDD:275371	6/21 (29%)
hb	NP_731267.1	C2H2 Zn finger	242..262	CDD:275368	3/19 (16%)
		C2H2 Zn finger	271..291	CDD:275368	7/19 (37%)
		zf-H2C2_2	283..308	CDD:463886	7/29 (24%)
		C2H2 Zn finger	299..319	CDD:275368	4/24 (17%)
		C2H2 Zn finger	327..345	CDD:275368	5/17 (29%)
		C2H2 Zn finger	707..727	CDD:275371	9/19 (47%)
		C2H2 Zn finger	735..757	CDD:275371	6/21 (29%)