Protein Alignment CG12769 and Ikzf3

DIOPT Version :9

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_035901.1
• Gene: Ikzf3 / 22780
• MGIID: 1342542
• Length: 507
• Species: Mus musculus
• Alignment Length: 693
• Identity: 141/693 - (20%)
• Similarity: 227/693 - (32%)
• Gaps: 218/693 - (31%)

  Fly    49 LKDAASSASESELQEPRSPTPTPTNLSTGPHSPPMTFRCERCDSFETSSRASLLLHVVQCLAGQA 113
            ::|...:......:|...||.:|..|:  .:|.|.....|..||.|..:...
Mouse     1 MEDIQPTVELKSTEEQPLPTESPDALN--DYSLPKPHEIENVDSREAPANED------------- 50

  Fly   114 AAAAAAAAASARLK------SEDLQEPENMSLGHMEGGKGDGQTGNGSSSSASS----------- 161
               ..|...|.::|      .|::.:||.|         ||.:......|.|..
Mouse    51 ---EDAGEDSMKVKDEYSDRDENIMKPEPM---------GDAEESEMPYSYAREYSDYESIKLER 103

  Fly   162 -SPAGNSGGGGGGNSSSRKVFECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLA 225
             .|..||...||       ...||||.:...:...:..||..|||.:|::|..|...|.:|.:|.
Mouse   104 HVPYDNSRPTGG-------KMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLL 161

  Fly   226 EHFTTHTKTLPYHCPICNRGFQRQIAMRAHFQNEHVGQHDLVK--TCPLC--SYRAGSMKSLRIH 286
            .|...||...|:.|.:||...||:.|:..|.:.     |.:.|  .|..|  ||:..|  ||..|
Mouse   162 RHIKLHTGEKPFKCHLCNYACQRRDALTGHLRT-----HSVEKPYKCEFCGRSYKQRS--SLEEH 219

  Fly   287 FFNRHGIDLDNPGPGGTSSLLLALESQASAAAAAAAASYVPPGLSPVPVQSQSQQQQQQQVAPPA 351
             ..|....|.||..|..:|    :|::...|...:..:.|...|                    |
Mouse   220 -KERCRAFLQNPDLGDAAS----VEARHIKAEMGSERALVLDRL--------------------A 259

  Fly   352 SDSGESMRSLENATPPMHFLTPHVEISTLGESGNTELFNLICVWRESALQGNNN-----NNNNNN 411
            |:..:...|:     |..|         :||             :......|.|     ...|..
Mouse   260 SNVAKRKSSM-----PQKF---------IGE-------------KRHCFDANYNPGYMYEKENEM 297

  Fly   412 CATNNNNNINGASNNCNSISNGNAESNGDKVKDRALIMQSPVELPMDCNTKATPITSSTTASSLS 476
            ..|   ..::.|.|  |:||...||:           ::..|:.|....::..|:.|
Mouse   298 MQT---RMMDQAIN--NAISYLGAEA-----------LRPLVQTPPAPTSEMVPVIS-------- 338

  Fly   477 GGLKSHHQHPHHHHHHHHHHENHITPSISLIPIKQEPMSEDMDKKDLMNGSDPSSDTEQASNNNN 541
                                        |:.||.       :.:.|:.||:....:
Mouse   339 ----------------------------SVYPIA-------LTRADMPNGAPQEME--------- 359

  Fly   542 SSSNNNRITSLIKVSPLKSLLREDLKRRICAKANNRITRNATPLESNNNNSVLSNSLSNGSGRGS 606
                ..||....|:.|.:..|           :.|...:::|..:||:.:   ...|...|....
Mouse   360 ----KKRILLPEKILPSERGL-----------SPNNSAQDSTDTDSNHED---RQHLYQQSHVVL 406

  Fly   607 PGVNGGSGGGGGGGPPTPATPSATNGASSTPIC-NGTITSTGQDGDLLINRKLILTCHFCGIEFP 670
            |....|.       |.....|.:.......||| ..:|....::|:::.    :..|..|.:.|.
Mouse   407 PQARNGM-------PLLKEVPRSFELLKPPPICLRDSIKVINKEGEVMD----VFRCDHCHVLFL 460

  Fly   671 DETLYFLHKGCHCESNPWRCNICGEQLNNVYEFNSHLLSKSHQ 713
            |..::.:|.|||...:|:.||:||.:.::.|||:||:....|:
Mouse   461 DYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	6/19 (32%)
		zf-H2C2_2	195..218	CDD:290200	8/22 (36%)
		C2H2 Zn finger	211..231	CDD:275368	6/19 (32%)
		C2H2 Zn finger	239..255	CDD:275368	6/15 (40%)
		C2H2 Zn finger	662..689	CDD:275371	9/26 (35%)
		C2H2 Zn finger	690..712	CDD:275371	9/21 (43%)
Ikzf3	NP_035901.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..85		21/110 (19%)
		COG5048	<105..>218	CDD:227381	40/126 (32%)
		C2H2 Zn finger	119..139	CDD:275368	6/19 (32%)
		zf-H2C2_2	132..156	CDD:290200	9/23 (39%)
		C2H2 Zn finger	147..167	CDD:275368	6/19 (32%)
		zf-H2C2_2	159..182	CDD:290200	8/22 (36%)
		C2H2 Zn finger	175..195	CDD:275368	7/24 (29%)
		zf-H2C2_2	191..212	CDD:290200	7/25 (28%)
		C2H2 Zn finger	203..219	CDD:275368	7/17 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..396		6/39 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4303
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960