Protein Alignment CG12769 and ehn-3

DIOPT Version :10

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_001023615.1
• Gene: ehn-3 / 191363
• WormBaseID: WBGene00001223
• Length: 262
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 96/542 - (17%)
• Similarity: 148/542 - (27%)
• Gaps: 295/542 - (54%)

  Fly   182 ECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTTHTKT-LPYHCPI--CN 243
            :||:|:.||||..|:.|||:.|:|.|.:||:.|::.|||.|.:.||..||.|. ..:.|||  ||
 Worm     3 KCDICHQKFSNKTNLNRHKVMHSGKKKFECQFCRRPFFRNDRMKEHMMTHIKKGNTFECPITACN 67

  Fly   244 RGFQRQIAMRAHFQNEHVGQHDLVKTCPLCSYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLLL 308
            ..|....:::.|..:||:.:......|..|           |.:||             :|..||
 Worm    68 SKFNSFTSLQFHVDSEHIIRGSSPAKCKSC-----------IKWFN-------------SSHRLL 108

  Fly   309 ALESQASAAAAAAAASYVPPGLSPVPVQSQSQQQQQQQVAPPASDSGESMRSLENATPPMHFLTP 373
                                                                       :||.|.
 Worm   109 -----------------------------------------------------------LHFHTA 114

  Fly   374 HVEISTLGESGNTELFNLICVWRESALQGNNNNNNNNNCATNNNNNINGASNNCNSISNGNAESN 438
            |::        :|:.|:.
 Worm   115 HLD--------HTKFFSF----------------------------------------------- 124

  Fly   439 GDKVKDRALIMQSPVELPMDCNTKATPITSSTTASSLSGGLKSHHQHPHHHHHHHHHHENHITPS 503
                                   |..||...:|.|.|:
 Worm   125 -----------------------KPAPILPKSTTSILN--------------------------- 139

  Fly   504 ISLIPIKQEPMSEDMDKKDLMNGSDPSSDTEQASNNNNSSSNNNRITSLIK--VSPLKSLLREDL 566
                |||.   .:|.|                            ||....|  ::||..|
 Worm   140 ----PIKN---PDDFD----------------------------RIFDFFKTEIAPLFPL----- 164

  Fly   567 KRRICAKANNRITRNATPLESNNNNSVLSNSLSNGSGRGSPGVNGGSGGGGGGGPPTPATPSAT- 630
                      ..|.:..||...:.:...:..||                      |||:|...|
 Worm   165 ----------HSTVSQAPLPQCSRSVKSAKELS----------------------PTPSTEIETP 197

  Fly   631 -----NGASSTPICNGTITSTGQDGDLLINRKLILTCHFCGIEFPDETLYFLHKGCHCESNPWRC 690
                 :|..|                        ..|.:|.|.|.|:.:::||.|.|.:..|::|
 Worm   198 EEEELDGPES------------------------WYCDYCKIRFDDKVMWYLHSGLHSDDIPFKC 238

  Fly   691 NICGEQLNNVYEFNSHLLSKSH 712
            ::||...:..|:|.:||:..:|
 Worm   239 SLCGSLCDGKYDFAAHLVYANH 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	11/19 (58%)
		zf-H2C2_2	195..218	CDD:463886	10/22 (45%)
		C2H2 Zn finger	211..231	CDD:275368	8/19 (42%)
		C2H2 Zn finger	239..255	CDD:275368	6/17 (35%)
		C2H2 Zn finger	662..689	CDD:275371	10/26 (38%)
		C2H2 Zn finger	690..712	CDD:275371	7/21 (33%)
ehn-3	NP_001023615.1	C2H2 Zn finger	4..24	CDD:275368	11/19 (58%)
		C2H2 Zn finger	32..52	CDD:275368	8/19 (42%)
		C2H2 Zn finger	61..80	CDD:275368	6/18 (33%)