Protein Alignment CG12769 and ikzf2

DIOPT Version :10

• Sequence 1: NP_001286181.1
• Gene: CG12769 / 35770
• FlyBaseID: FBgn0033252
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: XP_012825489.1
• Gene: ikzf2 / 100144703
• XenbaseID: XB-GENE-1013632
• Length: 585
• Species: Xenopus tropicalis
• Alignment Length: 719
• Identity: 151/719 - (21%)
• Similarity: 244/719 - (33%)
• Gaps: 215/719 - (29%)

  Fly    43 AMALRSLKDAASSASESELQEPRSPTPTPTNLSTGPHSPPMTFRCERCDSFETS--------SRA 99
            |:.|:.|| |.:||.:.::...:  |..|.||.|.      |...||.|.:.||        ..:
 Frog    30 ALHLKKLK-AWNSAGDPDISTEK--TEQPKNLCTS------TMESERSDGYVTSDNEIVPETEHS 85

  Fly   100 SLLLHVVQCLAGQAAAAAAAAAASARLKSEDLQEPENMSLGHMEGGKG------------DGQTG 152
            ::.:.:..|......::....|::..:|.|...:.|         |:|            |.::|
 Frog    86 NMAIDLTSCTPNGQHSSPTHMASTNSVKMEMQSDDE---------GEGKPLRRDTPLQLQDDESG 141

  Fly   153 --------NGSSSSASSSPAGNSGGGGGGNSSSRKVFECDVCNMKFSNGANMRRHKMRHTGVKPY 209
                    ||.|.|.||......||....|..    .:||||.|.......:..||..|||.:|:
 Frog   142 LEEPLIDANGMSDSRSSQDMPLDGGIRLPNGK----LKCDVCGMVCIGPNVLMVHKRSHTGERPF 202

  Fly   210 ECRVCQKRFFRKDHLAEHFTTHTKTLPYHCPICNRGFQRQIAMRAHFQNEHVGQ-HDLVKTCPLC 273
            .|..|...|.:|.:|..|...|:...|:.||.|:...:|:.|:..|.:...||: |    .|..|
 Frog   203 HCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPH----KCNYC 263

  Fly   274 --SYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLL-------------LALESQASAAAAAAAA 323
              ||:..|  ||..|....|.. |.|.|......::             ..:|:..|
 Frog   264 GRSYKQRS--SLEEHKERCHNY-LQNVGMEAGQGIVHHASPMDECKNPETMMENNMS-------- 317

  Fly   324 SYVPPGLSPVPVQSQSQQQQQQQVAPPASDSGESMRSLENATPPMHFLTPHVEISTLGESGNTEL 388
              :.|...|..::..:....:::.:.|....||.:  :....|.:||...:.:.:.:.:|
 Frog   318 --LIPFERPAVIERLASNMGKRKSSTPQKFVGEKL--MRFGYPDLHFEMAYEKEAEIMQS----- 373

  Fly   389 FNLICVWRESALQGNNNNNNNNNCATNNNNNINGASNNCNSISNGNAESNGDKVKDRALIMQSPV 453
                                         ..::.|.||..:....:|.        |.||..|..
 Frog   374 -----------------------------QMMDQAINNAITYLGADAL--------RPLIHHSAA 401

  Fly   454 ELPMDCNTKATPITSSTTASSLSGGLKSHHQHPHH-----HHHHHHHHENHITPSISLIPIKQEP 513
            .:|     ...||.||         |.|...||..     .......::|::...||||..|..|
 Frog   402 AMP-----DVPPIVSS---------LYSQVYHPARVERPTSRETSDSNDNNMDGPISLIRPKNHP 452

  Fly   514 MSEDMDKKDLMNGSDPSSDTEQASNNNNSSSNNNRITSLIKVSPLKSLLREDLKRRICAKANNRI 578
            ...:....   |....::|:|.:..:..|...|:.:.|..|.||:..  :||.|.....|::
 Frog   453 QEREASPS---NSCLDTTDSESSHEDRQSYQGNHALNSKRKQSPVYP--KEDGKALDATKSS--- 509

  Fly   579 TRNATPLESNNNNSVLSNSLSNGSGRGSPGVNGGSGGGGGGGPPTPATPSATNGASSTPICNGTI 643
                  |.|:.:...:.||
 Frog   510 ------LGSSKDVYRVFNS---------------------------------------------- 522

  Fly   644 TSTGQDGDLLINRKLILTCHFCGIEFPDETLYFLHKGCHCESNPWRCNICGEQLNNVYEFNSHLL 708
                 :|:.:...|    |..|.:.|.|..:|.:|.|||...:|..|||||.:..:.|||:||::
 Frog   523 -----EGEQIRAFK----CEHCRVLFLDHVMYTIHMGCHGYRDPLECNICGHRSQDRYEFSSHIV 578

  Fly   709 SKSH 712
            ...|
 Frog   579 RGEH 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12769	NP_001286181.1	C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		zf-H2C2_2	195..218	CDD:463886	8/22 (36%)
		C2H2 Zn finger	211..231	CDD:275368	6/19 (32%)
		C2H2 Zn finger	239..255	CDD:275368	5/15 (33%)
		C2H2 Zn finger	662..689	CDD:275371	10/26 (38%)
		C2H2 Zn finger	690..712	CDD:275371	10/21 (48%)
ikzf2	XP_012825489.1	C2H2 Zn finger	176..196	CDD:275368	7/19 (37%)
		zf-H2C2_2	189..213	CDD:463886	9/23 (39%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		zf-H2C2_2	216..241	CDD:463886	7/24 (29%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		zf-H2C2_2	248..269	CDD:463886	8/24 (33%)
		C2H2 Zn finger	260..281	CDD:275368	8/22 (36%)