Protein Alignment CG14762 and slit3

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001072738.1
• Gene: slit3 / 780195
• XenbaseID: XB-GENE-991050
• Length: 1519
• Species: Xenopus tropicalis
• Alignment Length: 458
• Identity: 118/458 - (25%)
• Similarity: 184/458 - (40%)
• Gaps: 124/458 - (27%)

  Fly   133 QLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAF 197
            :||:..|.:..:.......|.:|.:|:|..|:|::|...||:.|:.||.:.|.:||: |:.||..
 Frog    61 RLDMDKNNITRITKTDFAGLKNLRVLHLEDNQISIIERGAFQDLKQLERMRLNKNKL-QVLPELL 124

  Fly   198 RGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMI 262
            ......:.||:|..|.:..:|:|:...::.:|.|::..|:|..|.:|.|..|:.|:.|.|.:|.|
 Frog   125 FQNNAKLTRLDLSENQIQGLPRKSFRGITDVKNLQLDNNQISCIEDGVFRALRELEILTLNNNNI 189

  Fly   263 TTVPANVFSHLTLLNSLELEGN------------------------------------KISVIDK 291
            |.:|...|:|:..:.:|.|..|                                    .::.:.|
 Frog   190 TRIPLTSFNHMPKIRTLRLHSNYLYCDCHLTWLSDWLRQRKTIGQFTFCMSPVHLRGFNVADVQK 254

  Fly   292 DAF----------------------------------KGLEE---NLQ----YLRLGDNQIHTIP 315
            ..|                                  |||.|   ||.    .:||..|.|..||
 Frog   255 KDFVCPGTQSEPPSCNANAVSCPSACTCSNNVVDCRGKGLTEIPANLPEGIIEIRLEQNSIKAIP 319

  Fly   316 SEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETL--- 377
            :....|..:|:.:|:..|.|:.:|.|||:|. .|||.|.|..|.|..:|..||:.|.||:.|
 Frog   320 AGVFTPYKKLKRIDISKNQISEIAADAFSGL-KSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLN 383

  Fly   378 -------------NLQN--------NKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPKL 421
                         :|||        ||||.|.:.:..| :.:::.:.:..||..|.|.|.|....
 Frog   384 ANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAP-LQSIQTLHLAQNPFVCDCHLKWLADY 447

  Fly   422 LED---------------LKNKDDEMSQKKKPLCHMSLDNR-----EYFVQAMPTEKMHCAGLNV 466
            |:|               |.||.....:.||..|..|.|.|     :.|:..:..||..|.|..|
 Frog   448 LQDNPIETSGARCTSPRRLANKRISQIKSKKFRCTGSEDYRSKFSGDCFMDLVCPEKCRCEGTIV 512

  Fly   467 SPS 469
            ..|
 Frog   513 DCS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		leucine-rich repeat	107..129	CDD:275380
		LRR	<131..410	CDD:443914	96/377 (25%)
		leucine-rich repeat	131..154	CDD:275380	4/20 (20%)
		leucine-rich repeat	155..178	CDD:275380	9/22 (41%)
		leucine-rich repeat	179..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	6/22 (27%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		leucine-rich repeat	276..300	CDD:275380	9/96 (9%)
		leucine-rich repeat	301..324	CDD:275380	8/26 (31%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	10/22 (45%)
slit3	NP_001072738.1	LRRNT	29..60	CDD:214470
		LRR	<58..>213	CDD:443914	47/152 (31%)
		leucine-rich repeat	60..82	CDD:275380	4/20 (20%)
		leucine-rich repeat	83..106	CDD:275380	9/22 (41%)
		leucine-rich repeat	107..130	CDD:275380	8/23 (35%)
		leucine-rich repeat	131..154	CDD:275380	6/22 (27%)
		leucine-rich repeat	155..178	CDD:275380	8/22 (36%)
		leucine-rich repeat	179..202	CDD:275380	9/22 (41%)
		leucine-rich repeat	203..305	CDD:275380	11/101 (11%)
		LRRCT	211..260	CDD:214507	3/48 (6%)
		LRRNT	276..307	CDD:214470	6/30 (20%)
		leucine-rich repeat	307..328	CDD:275380	7/20 (35%)
		LRR	<327..662	CDD:443914	56/191 (29%)
		leucine-rich repeat	329..352	CDD:275380	9/23 (39%)
		leucine-rich repeat	353..373	CDD:275380	9/19 (47%)
		leucine-rich repeat	377..400	CDD:275380	3/22 (14%)
		leucine-rich repeat	401..422	CDD:275380	6/21 (29%)
		leucine-rich repeat	425..516	CDD:275380	24/91 (26%)
		leucine-rich repeat	533..554	CDD:275380
		leucine-rich repeat	555..578	CDD:275380
		leucine-rich repeat	579..602	CDD:275380
		leucine-rich repeat	603..626	CDD:275380
		leucine-rich repeat	627..650	CDD:275380
		PCC	632..>719	CDD:188093
		leucine-rich repeat	651..741	CDD:275380
		LRR	<723..>855	CDD:443914
		leucine-rich repeat	742..772	CDD:275380
		leucine-rich repeat	773..796	CDD:275380
		leucine-rich repeat	797..820	CDD:275380
		leucine-rich repeat	821..842	CDD:275380
		PCC	826..>901	CDD:188093
		EGF	916..947	CDD:394967
		EGF_CA	952..989	CDD:238011
		EGF_CA	994..1027	CDD:238011
		EGF_CA	1031..1068	CDD:238011
		EGF_CA	1070..1106	CDD:238011
		LamG	1155..1308	CDD:238058
		GHB_like	1454..1517	CDD:473907