DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14762 and slit1b

DIOPT Version :9

Sequence 1:NP_001246198.1 Gene:CG14762 / 35768 FlyBaseID:FBgn0033250 Length:498 Species:Drosophila melanogaster
Sequence 2:NP_001030147.1 Gene:slit1b / 561685 ZFINID:ZDB-GENE-030722-4 Length:1532 Species:Danio rerio


Alignment Length:454 Identity:109/454 - (24%)
Similarity:178/454 - (39%) Gaps:122/454 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 QLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAF 197
            :||::.|.:..:.......|.||.||:|..|:|..|...||..|:.|:.|.|..|::.|: ||..
Zfish    62 RLDLNANNLTHIGKDDFAGLKHLRILHLMDNQIVSIDRGAFSDLKELDRLRLNRNRLQQL-PELL 125

  Fly   198 RGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMI 262
            ......:.||:|..|::..||::|....:.:|.|::.:|.|..|.:|.|..::.|:.|.|.:|.|
Zfish   126 FLKNPALSRLDLSENNIQMIPRRAFRGATDIKNLQLDKNHISCIEDGAFRAMRVLEVLTLNNNNI 190

  Fly   263 TTVPANVFSHLTLL-------NSL-----------------------------ELEGNKISVIDK 291
            :.:|.:.|:|:..|       |||                             .|.|..::.:.|
Zfish   191 SAIPISSFNHMPKLRTFRLHWNSLRCDCQLSWLSQWLRQRPALGLYTQCSSPAHLHGLNLAELQK 255

  Fly   292 DAF-----------------------------------KGL-------EENLQYLRLGDNQIHTI 314
            ..|                                   |||       .|::..:||..|.|.::
Zfish   256 KDFTCAGALDSSPQPCGLASGSCPPMCSCTNNIVDCRGKGLTAIPANMPESMTEIRLEQNGIKSV 320

  Fly   315 PSEALRPLHRLRHLDLRNNNINVLAEDAFTG---------FGDSLT--------------FLNLQ 356
            |..|.....|||.:||.||.|:.:|.|||.|         :|:.:|              .|.|.
Zfish   321 PPGAFSSYKRLRRIDLSNNQISEIAPDAFHGLRSLNSLVLYGNKITDLPRGVFDGLSALELLLLN 385

  Fly   357 KNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPKL 421
            .|.|..:...:|::|.:|..|:|.:||:|.:.:....| :.:::.:.:..||..|.|.|.|....
Zfish   386 ANKIHCVRVNVFQDLENLSLLSLYDNKIQTLAKGTFAP-LKSIQTLHLAQNPFVCDCGLKWLADF 449

  Fly   422 LED---------------LKNKDDEMSQKKKPLCHMSLDNREYFVQAMPTEKMH--CAGLNVSP 468
            |..               |.||.....:.||..|  |....:|::......:|:  |....|.|
Zfish   450 LRSNPIETSGARCSSPRRLANKRISQIKSKKFRC--SAAKEQYYIPGSEDTRMNKDCNSKPVCP 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14762NP_001246198.1 leucine-rich repeat 85..105 CDD:275380
LRR_RI 93..384 CDD:238064 87/351 (25%)
leucine-rich repeat 107..129 CDD:275380
leucine-rich repeat 131..154 CDD:275380 4/20 (20%)
LRR_8 154..214 CDD:290566 22/59 (37%)
leucine-rich repeat 155..178 CDD:275380 10/22 (45%)
leucine-rich repeat 179..203 CDD:275380 7/23 (30%)
leucine-rich repeat 204..227 CDD:275380 7/22 (32%)
LRR_8 226..286 CDD:290566 21/95 (22%)
leucine-rich repeat 228..251 CDD:275380 7/22 (32%)
leucine-rich repeat 252..275 CDD:275380 8/22 (36%)
LRR_8 276..335 CDD:290566 25/136 (18%)
leucine-rich repeat 276..300 CDD:275380 11/101 (11%)
leucine-rich repeat 301..324 CDD:275380 6/22 (27%)
leucine-rich repeat 325..349 CDD:275380 13/32 (41%)
LRR_8 349..409 CDD:290566 15/73 (21%)
leucine-rich repeat 350..373 CDD:275380 7/36 (19%)
slit1bNP_001030147.1 LRR_8 306..365 CDD:290566 20/58 (34%)
LRR_4 329..369 CDD:289563 15/39 (38%)
leucine-rich repeat 331..354 CDD:275380 12/22 (55%)
LRR_8 353..437 CDD:290566 16/84 (19%)
leucine-rich repeat 355..375 CDD:275380 2/19 (11%)
leucine-rich repeat 403..426 CDD:275380 7/23 (30%)
leucine-rich repeat 427..482 CDD:275380 12/54 (22%)
TPKR_C2 435..>465 CDD:301599 7/29 (24%)
LRR_RI <511..625 CDD:238064 1/1 (100%)
leucine-rich repeat 519..538 CDD:275380
leucine-rich repeat 539..563 CDD:275380
LRR_8 562..622 CDD:290566
leucine-rich repeat 564..587 CDD:275380
leucine-rich repeat 588..611 CDD:275380
LRR_8 611..670 CDD:290566
leucine-rich repeat 612..635 CDD:275380
leucine-rich repeat 636..659 CDD:275380
leucine-rich repeat 660..753 CDD:275380
LRRCT 668..717 CDD:214507
LRRNT 732..764 CDD:214470
leucine-rich repeat 754..784 CDD:275380
LRR_8 783..843 CDD:290566
LRR_4 784..825 CDD:289563
leucine-rich repeat 785..808 CDD:275380
leucine-rich repeat 809..829 CDD:275380
leucine-rich repeat 833..856 CDD:275380
LRRCT 865..914 CDD:214507
EGF_CA 929..961 CDD:238011
EGF_CA 968..1001 CDD:238011
EGF_CA 1003..1039 CDD:238011
EGF_CA <1051..1079 CDD:238011
LRRNT 30..61 CDD:214470
leucine-rich repeat 41..58 CDD:275380
leucine-rich repeat 60..83 CDD:275380 4/20 (20%)
LRR_8 61..118 CDD:290566 19/55 (35%)
LRR_4 61..98 CDD:289563 11/35 (31%)
LRR_RI <84..217 CDD:238064 43/133 (32%)
leucine-rich repeat 84..107 CDD:275380 10/22 (45%)
leucine-rich repeat 108..131 CDD:275380 7/23 (30%)
LRR_8 130..190 CDD:290566 18/59 (31%)
leucine-rich repeat 132..155 CDD:275380 7/22 (32%)
leucine-rich repeat 156..179 CDD:275380 7/22 (32%)
leucine-rich repeat 180..203 CDD:275380 8/22 (36%)
leucine-rich repeat 204..247 CDD:275380 5/42 (12%)
LRRCT 212..260 CDD:214507 7/47 (15%)
leucine-rich repeat 248..330 CDD:275380 12/81 (15%)
LRRNT 278..309 CDD:214470 4/30 (13%)
EGF_CA 1082..1118 CDD:238011
LamG 1160..1314 CDD:238058
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.