Protein Alignment CG14762 and zgc:153913

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001073448.1
• Gene: zgc:153913 / 559700
• ZFINID: ZDB-GENE-061103-397
• Length: 496
• Species: Danio rerio
• Alignment Length: 490
• Identity: 121/490 - (24%)
• Similarity: 203/490 - (41%)
• Gaps: 93/490 - (18%)

  Fly    10 CTMVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKSMG 74
            |.:|:.|::.|...|             .|||     ||.|.   :|..::|...
Zfish     5 CAVVLLVLIHLYCGV-------------CCPE-----PCQCF---SGSKLVCSDD---------- 38

  Fly    75 TLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENA------LSSLGAGLTQ 133
                          |..:||     |.::..:|.|.:..|.:..:::.:      ||.|
Zfish    39 --------------RMKSLP-----VNISTQVRELIVVASGIPDLDQQSFPETLRLSKL------ 78

  Fly   134 LDVSLNQM-KTVPSQALQHLFHLLILNLNHNKITV-IHNNAFEGLETLEILTLYENKITQIDPEA 196
              |.||.| |:|..:|.:.|..|..|.::.|...: :....|..|..|..|.|..||::.:|...
Zfish    79 --VFLNGMLKSVSGEAFERLVELRELEISGNICWMSLDIQTFSSLTNLTRLLLNNNKLSGVDAGL 141

  Fly   197 FRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNM 261
            |..|. .::.|.|.||.|:.:..:....|..|::|::..|:|.::|...|:....|..|.|..|.
Zfish   142 FHSLH-QLEMLQLRGNGLSFLSGRLFQRLHRLQELDLSFNQISSLSTELFQNNSELRVLSLQANK 205

  Fly   262 ITTVPANVFSHLTLLNSLELEGNKISVIDKDAF----------KGLEENL-----------QYLR 305
            |..:|..:|:||..|..|.|..|.|.|:...:|          |.|.|.|           .||.
Zfish   206 IPNLPDGIFTHLDHLQELNLRSNLIRVLTPGSFPASLKTLILKKNLLEKLTNAVFHTLHYITYLD 270

  Fly   306 LGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFEN 370
            |..|.:..:|::..:.|..|..|||..|.|:.||...|.|. .|:..:.||||.:..:.:.|.::
Zfish   271 LSQNSLTEVPADLFQNLISLETLDLSENRISTLAGSVFKGL-FSIKSVYLQKNSLISVDAHLLKD 334

  Fly   371 LNSLETLNLQNNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPKLLEDLKNKDDEMSQK 435
            .:.|:.|:|.||.|:.||....|. :|...:.::..||.:|.|.:.:|   .:.||.....:...
Zfish   335 QHDLQLLDLSNNSLRSIPSGFFED-LDFQCVFELRGNPWSCDCGIHYF---YDWLKYNHKHVKDL 395

  Fly   436 KKPLCHMSLDNREYFVQAMPTEKMHCAGLNVSPSP 470
            .:..|......:.:.::::..|::.|:..:.|.||
Zfish   396 SRVSCEAPELIQGHNLRSVDREQLVCSRNSSSNSP 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	4/19 (21%)
		leucine-rich repeat	107..129	CDD:275380	6/27 (22%)
		LRR	<131..410	CDD:443914	87/301 (29%)
		leucine-rich repeat	131..154	CDD:275380	8/23 (35%)
		leucine-rich repeat	155..178	CDD:275380	5/23 (22%)
		leucine-rich repeat	179..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	6/22 (27%)
		leucine-rich repeat	228..251	CDD:275380	6/22 (27%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		leucine-rich repeat	276..300	CDD:275380	9/33 (27%)
		leucine-rich repeat	301..324	CDD:275380	7/33 (21%)
		leucine-rich repeat	325..349	CDD:275380	10/23 (43%)
		leucine-rich repeat	350..373	CDD:275380	5/22 (23%)
zgc:153913	NP_001073448.1	leucine-rich repeat	75..98	CDD:275380	11/30 (37%)
		LRR	<142..>352	CDD:443914	62/211 (29%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	9/22 (41%)
		leucine-rich repeat	220..241	CDD:275380	7/20 (35%)
		leucine-rich repeat	242..265	CDD:275380	4/22 (18%)
		leucine-rich repeat	266..289	CDD:275380	6/22 (27%)
		leucine-rich repeat	290..313	CDD:275380	10/23 (43%)
		leucine-rich repeat	314..337	CDD:275380	5/22 (23%)
		leucine-rich repeat	338..359	CDD:275380	9/21 (43%)
		PCC	342..>427	CDD:188093	18/88 (20%)