DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14762 and lingo4b

DIOPT Version :9

Sequence 1:NP_001246198.1 Gene:CG14762 / 35768 FlyBaseID:FBgn0033250 Length:498 Species:Drosophila melanogaster
Sequence 2:NP_001082850.1 Gene:lingo4b / 559074 ZFINID:ZDB-GENE-091214-3 Length:604 Species:Danio rerio


Alignment Length:510 Identity:123/510 - (24%)
Similarity:206/510 - (40%) Gaps:109/510 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 CPEQSEIAPCICTVKKNGLDILCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLA 103
            ||::       |:..::.|::.|.:..|..:.:.:.|                            
Zfish    29 CPQR-------CSCSRDPLEVNCSSRHLTAVPEGLPT---------------------------- 58

  Fly   104 LDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVI 168
             :.:.|.:..:.|..:.....||| :.|..||:|.|.:..:..:..|.|.:|..|.:.:|::.::
Zfish    59 -NAKRLDLSGNQLKTLARRQFSSL-SKLEDLDLSENIISMIEVETFQGLKNLRYLRIKNNRLKIL 121

  Fly   169 HNNAFEGLETLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEI 233
            ....|.||..|..|.:.||:|.......||.: .::::|:.|.|||..|.|:|...|..||:|.:
Zfish   122 PVGVFSGLSNLRRLDISENEILVFLDYTFRDM-INLQQLDAGENDLVFISQRAFVGLQALKELNV 185

  Fly   234 QENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLE-LEGNKISVIDKDAFKGL 297
            ..:.:.:|.......||||..|.|....|:.:|.|.|..|..|.:|: |..:.:.:::.::..||
Zfish   186 DRSNLTSIPTEALSQLQSLTKLRLRKLTISVLPNNAFRRLHQLRTLQILHWSSLEMLNSNSLVGL 250

  Fly   298 EENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQK----- 357
              ||..|.|.:..:..||...||.|..|::|||..|.|..:..:.   .||   .|.||:     
Zfish   251 --NLTTLVLTNCNLSAIPYSPLRHLAYLQYLDLSYNPITSIQGNL---LGD---LLRLQELHLVG 307

  Fly   358 -NDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPV--IDTLRIIDITDNPLNCSCELTWFP 419
             |.:::.|. .|..|:....||:.:|:|..:.:.....|  :.|||   :..|||.|.|.|.|  
Zfish   308 GNLLRIEPG-AFRGLSRFRLLNVSSNRLSTLEESAFHSVGNLQTLR---LDRNPLACDCRLLW-- 366

  Fly   420 KLLEDLKNKD-DEMSQKKKPLCHMSLDNREYFVQAMPTEKMHC----------------AGLNVS 467
             ::...:..| |.......||.|.....|::....:|. ...|                .|:.|.
Zfish   367 -VMRRRRRLDFDGRQPTCSPLNHQRKAFRDFSEAELPV-VFTCRQAQILNRQLQDISVIEGMRVH 429

  Fly   468 --------PSP------------TSGGLMRILQVNIL----AQIA-----VCSVA 493
                    |||            :|.|.:|:|....|    ||:.     :||.|
Zfish   430 FDCKADGYPSPSITWLSAQQSALSSAGRVRVLTNGSLQISYAQVQDSGTYLCSAA 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14762NP_001246198.1 leucine-rich repeat 85..105 CDD:275380 0/19 (0%)
LRR_RI 93..384 CDD:238064 81/297 (27%)
leucine-rich repeat 107..129 CDD:275380 5/21 (24%)
leucine-rich repeat 131..154 CDD:275380 7/22 (32%)
LRR_8 154..214 CDD:290566 16/59 (27%)
leucine-rich repeat 155..178 CDD:275380 6/22 (27%)
leucine-rich repeat 179..203 CDD:275380 7/23 (30%)
leucine-rich repeat 204..227 CDD:275380 9/22 (41%)
LRR_8 226..286 CDD:290566 18/60 (30%)
leucine-rich repeat 228..251 CDD:275380 5/22 (23%)
leucine-rich repeat 252..275 CDD:275380 8/22 (36%)
LRR_8 276..335 CDD:290566 19/59 (32%)
leucine-rich repeat 276..300 CDD:275380 5/24 (21%)
leucine-rich repeat 301..324 CDD:275380 8/22 (36%)
leucine-rich repeat 325..349 CDD:275380 7/23 (30%)
LRR_8 349..409 CDD:290566 16/67 (24%)
leucine-rich repeat 350..373 CDD:275380 7/28 (25%)
lingo4bNP_001082850.1 LRRNT 28..61 CDD:214470 7/67 (10%)
leucine-rich repeat 41..62 CDD:275380 3/49 (6%)
LRR <56..304 CDD:227223 75/286 (26%)
leucine-rich repeat 63..83 CDD:275380 5/20 (25%)
leucine-rich repeat 84..107 CDD:275380 7/22 (32%)
leucine-rich repeat 108..131 CDD:275380 6/22 (27%)
leucine-rich repeat 132..155 CDD:275380 7/23 (30%)
leucine-rich repeat 156..179 CDD:275380 9/22 (41%)
leucine-rich repeat 180..203 CDD:275380 5/22 (23%)
leucine-rich repeat 204..251 CDD:275380 13/48 (27%)
leucine-rich repeat 228..250 CDD:275380 3/21 (14%)
leucine-rich repeat 252..275 CDD:275380 8/22 (36%)
leucine-rich repeat 276..297 CDD:275380 8/26 (31%)
LRR_8 299..358 CDD:316378 15/62 (24%)
leucine-rich repeat 300..321 CDD:275380 5/21 (24%)
leucine-rich repeat 324..344 CDD:275380 4/19 (21%)
I-set 415..498 CDD:254352 15/70 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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