Protein Alignment CG14762 and lrfn5b

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_683575.2
• Gene: lrfn5b / 555839
• ZFINID: ZDB-GENE-080327-20
• Length: 765
• Species: Danio rerio
• Alignment Length: 425
• Identity: 93/425 - (21%)
• Similarity: 138/425 - (32%)
• Gaps: 178/425 - (41%)

  Fly    19 LLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKSMGTLKGKSPII 83
            :|.|.:|..|:.....:.||||::     |||.|....|..||:.
Zfish     3 MLLVYLMVVVMALKAQKIQVCPKR-----CICQVLPPNLATLCDK-------------------- 42

  Fly    84 FYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQA 148
                         :|.:|:..:|...|:.
Zfish    43 -------------KGLLFVPPNIDRRTVE------------------------------------ 58

  Fly   149 LQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGND 213
                     |.|..|.||.|....|..:..|..|||..|.|..:.|.||              ||
Zfish    59 ---------LRLGDNFITGIKRKDFANMTKLVDLTLSRNTIGSVAPHAF--------------ND 100

  Fly   214 LTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNS 278
            |.|           |:.|.:..|::..|:...|.|:..|..|||.:|.:|.:....|:.|..|..
Zfish   101 LEN-----------LRALHLDSNRLTHITNDTFSGMSKLHHLILNNNQLTYIHIGAFNDLLALEE 154

  Fly   279 LELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAF 343
            |:                    |.|     |.:...|..|::.:..|..|:|.:|.||.:.|..|
Zfish   155 LD--------------------LSY-----NNLEGAPWIAIQLMISLHTLNLDHNMINYIPEGTF 194

  Fly   344 TGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLRI------- 401
            :|         |||                |:.|::.:|||.::|.|   ||.....:
Zfish   195 SG---------LQK----------------LKRLDVTSNKLHKLPPD---PVFQRAGVLATSGVL 231

  Fly   402 ------IDITDNPLNCSCELTWFPKLLEDLKNKDD 430
                  :....|||:|:|||.|    |..|:.:||
Zfish   232 GASTFALSFGGNPLHCNCELLW----LRRLRREDD 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	2/19 (11%)
		leucine-rich repeat	107..129	CDD:275380	1/21 (5%)
		LRR	<131..410	CDD:443914	64/291 (22%)
		leucine-rich repeat	131..154	CDD:275380	0/22 (0%)
		leucine-rich repeat	155..178	CDD:275380	7/22 (32%)
		leucine-rich repeat	179..203	CDD:275380	9/23 (39%)
		leucine-rich repeat	204..227	CDD:275380	4/22 (18%)
		leucine-rich repeat	228..251	CDD:275380	6/22 (27%)
		leucine-rich repeat	252..275	CDD:275380	8/22 (36%)
		leucine-rich repeat	276..300	CDD:275380	2/23 (9%)
		leucine-rich repeat	301..324	CDD:275380	5/22 (23%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	3/22 (14%)
lrfn5b	XP_683575.2	leucine-rich repeat	56..79	CDD:275380	8/67 (12%)
		LRR	<58..>213	CDD:443914	58/274 (21%)
		leucine-rich repeat	80..103	CDD:275380	12/36 (33%)
		leucine-rich repeat	104..127	CDD:275380	6/22 (27%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	7/47 (15%)
		leucine-rich repeat	176..199	CDD:275380	10/31 (32%)
		Ig	290..377	CDD:472250
		Ig strand B	307..311	CDD:409353
		Ig strand C	320..324	CDD:409353
		Ig strand E	343..347	CDD:409353
		Ig strand F	357..362	CDD:409353
		Ig strand G	370..373	CDD:409353
		fn3	426..495	CDD:394996