Protein Alignment CG14762 and Lrrtm4

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_017448300.1
• Gene: Lrrtm4 / 500219
• RGDID: 1560707
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 126/494 - (25%)
• Similarity: 205/494 - (41%)
• Gaps: 128/494 - (25%)

  Fly     1 MAGIQLQSGCTMVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTD 65
            |.|.:|.:....:..:::|...|::..:.|    ..:.||:.     |.|    :|..:.||:..
  Rat     1 MPGFRLITQLKGMSVLLVLFPTLLLVMLTG----AQRACPKN-----CRC----DGKIVYCESHA 52

  Fly    66 LAHITKSM-GTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSLGA 129
            .|.|.::: |..:|       |.||.|::.||:...|                           |
  Rat    53 FADIPENISGGSQG-------LSLRFNSIQKLKSNQF---------------------------A 83

  Fly   130 GLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDP 194
            ||.|                     |:.|.|:||.|:.:..:||:|:..|:.|.|..||||.:..
  Rat    84 GLNQ---------------------LIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHN 127

  Fly   195 EAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAH 259
            :.|..:.:                         |:.|::..||::|:....|:||:.|..|.|..
  Rat   128 KTFHPVPN-------------------------LRNLDLSYNKLQTLQSEQFKGLRKLIILHLRS 167

  Fly   260 NMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHR 324
            |.:.|||..||.....|:.|:|..|::..:.::||.||.: |:.|.|..||...|.......|..
  Rat   168 NSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLK-LKELHLEHNQFSKINFAHFPRLFN 231

  Fly   325 LRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQ 389
            ||.:.|:.|.|..::: ..|....||..|:|..|||:.:....|:.|.:|:.|||.:|||..:.|
  Rat   232 LRSIYLQWNRIRSVSQ-GLTWTWSSLHTLDLSGNDIQAIEPGTFKCLPNLQKLNLDSNKLTNVSQ 295

  Fly   390 DIMEPVIDTLRIIDITDNPLNCS---CELTWFPKLLEDLK-NKDDEMSQKKKPLC----HMS--- 443
            :.:...| :|..|.::.|...||   |.|.::   |::.| ||:..|      :|    |:.
  Rat   296 ETVNAWI-SLISITLSGNMWECSRSICPLFYW---LKNFKGNKESTM------ICAGPKHIQGEK 350

  Fly   444 -LDNREYF-----VQAMPTEKMHCAGLNVS-----PSPT 471
             .|..|.:     ||.:.||:.|.|.....     |.||
  Rat   351 VSDAVETYNICSDVQVVNTERSHLAPQTPQKPPFFPKPT 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	7/19 (37%)
		leucine-rich repeat	107..129	CDD:275380	0/21 (0%)
		LRR	<131..410	CDD:443914	78/278 (28%)
		leucine-rich repeat	131..154	CDD:275380	2/22 (9%)
		leucine-rich repeat	155..178	CDD:275380	9/22 (41%)
		leucine-rich repeat	179..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	0/22 (0%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		leucine-rich repeat	276..300	CDD:275380	8/23 (35%)
		leucine-rich repeat	301..324	CDD:275380	7/22 (32%)
		leucine-rich repeat	325..349	CDD:275380	6/23 (26%)
		leucine-rich repeat	350..373	CDD:275380	8/22 (36%)
Lrrtm4	XP_017448300.1	leucine-rich repeat	44..62	CDD:275380	4/17 (24%)
		leucine-rich repeat	65..87	CDD:275380	11/55 (20%)
		LRR	67..>312	CDD:443914	86/320 (27%)
		leucine-rich repeat	88..111	CDD:275380	9/22 (41%)
		leucine-rich repeat	112..135	CDD:275380	8/22 (36%)
		leucine-rich repeat	136..159	CDD:275380	8/22 (36%)
		leucine-rich repeat	160..183	CDD:275380	9/22 (41%)
		leucine-rich repeat	184..207	CDD:275380	8/22 (36%)
		leucine-rich repeat	208..231	CDD:275380	7/22 (32%)
		leucine-rich repeat	232..255	CDD:275380	6/23 (26%)
		leucine-rich repeat	256..279	CDD:275380	8/22 (36%)
		leucine-rich repeat	304..316	CDD:275378	3/11 (27%)