DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14762 and atk

DIOPT Version :9

Sequence 1:NP_001246198.1 Gene:CG14762 / 35768 FlyBaseID:FBgn0033250 Length:498 Species:Drosophila melanogaster
Sequence 2:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster


Alignment Length:564 Identity:137/564 - (24%)
Similarity:236/564 - (41%) Gaps:127/564 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 MVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKSM--- 73
            |::.:.|||       .:|....:.:.||....|.||.|:::...:.|.|..::|..|...:   
  Fly     2 MLLPIFLLL-------CIGINLIRAESCPPSQAILPCRCSLRGKEIQIWCSHSNLPQIMDGLKAV 59

  Fly    74 -GTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVS 137
             ..:||:   |..|.|.:|.||.|.|..|.:|.|..|.:.::|:..:....|:.|..||.::.|.
  Fly    60 ERNIKGR---IDELVLENNQLPALPGRFFGSLQIVRLMLRHNSIERVSNGWLNELENGLVEIFVV 121

  Fly   138 LNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGLED 202
            ..|::::|:::|..:.::|.:.:...::.  |...|.||.:|..|::....:.::....||    
  Fly   122 EPQLRSIPAESLNGMINMLAITIQSEELK--HLPDFSGLLSLTYLSVQTGALQELPSHLFR---- 180

  Fly   203 HIKRLN----LGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMIT 263
            |:.:|.    .||:.||.:.......|.:||.|::..|.:..|.......|.:|.||.|:||.|:
  Fly   181 HLPKLQHIHITGGSGLTRLEAGLFDGLISLKNLDLSHNGLNWIHLRALSRLPNLVSLKLSHNQIS 245

  Fly   264 TV--PANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDN--------------QIH 312
            .|  ...:...|..|..|.|:.|.|:||:..:|..| .||..|.|.||              |:.
  Fly   246 DVGMVGRIVKDLEHLKKLRLDNNLITVIEDGSFVDL-PNLSELHLNDNRITELQYGAFLRTPQLK 309

  Fly   313 TI-----------PS-----------------------EALR----PLHRLRHLDLRNNNINVLA 339
            ||           |.                       ||||    .|.|||:||:..|.::.|.
  Fly   310 TIYLQNNLIRRIHPESLLQASGSGVEAVHMYNNEIGHVEALRALLDALPRLRYLDMSGNLLSELP 374

  Fly   340 EDAFTGFGDSLTFLNLQKNDIKV--------LPSLL----------------FENLNSLETLNLQ 380
            ..|..|.| :|..|:|..|.:::        :|:|.                |.||..|:.|:|.
  Fly   375 YGALRGHG-TLEQLHLNHNHLRLIERDALMAMPALRELRMRNNSLSSDLPLPFWNLPGLKGLDLA 438

  Fly   381 NNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPK------LLEDLKNKDDEMSQ-KKKP 438
            .|:..|:...::.. :.:||.:|:::|.|   .||.  |.      |||.|....:|::: ....
  Fly   439 QNQFARVDSQLLAG-LPSLRRLDLSENGL---IELA--PNSFRHNPLLETLNISSNELTKIHSST 497

  Fly   439 LCHM--------SLDNREYFVQAMP--TEKMHCAGLNVSPSPTS 472
            |.|:        |.:..:..:..:|  .|::...|..::..|.:
  Fly   498 LIHLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSLPAA 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14762NP_001246198.1 leucine-rich repeat 85..105 CDD:275380 8/19 (42%)
LRR_RI 93..384 CDD:238064 95/372 (26%)
leucine-rich repeat 107..129 CDD:275380 4/21 (19%)
leucine-rich repeat 131..154 CDD:275380 5/22 (23%)
LRR_8 154..214 CDD:290566 13/63 (21%)
leucine-rich repeat 155..178 CDD:275380 5/22 (23%)
leucine-rich repeat 179..203 CDD:275380 4/23 (17%)
leucine-rich repeat 204..227 CDD:275380 6/26 (23%)
LRR_8 226..286 CDD:290566 19/61 (31%)
leucine-rich repeat 228..251 CDD:275380 6/22 (27%)
leucine-rich repeat 252..275 CDD:275380 9/24 (38%)
LRR_8 276..335 CDD:290566 30/110 (27%)
leucine-rich repeat 276..300 CDD:275380 9/23 (39%)
leucine-rich repeat 301..324 CDD:275380 14/74 (19%)
leucine-rich repeat 325..349 CDD:275380 9/23 (39%)
LRR_8 349..409 CDD:290566 18/83 (22%)
leucine-rich repeat 350..373 CDD:275380 9/46 (20%)
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380 8/19 (42%)
leucine-rich repeat 90..113 CDD:275380 5/22 (23%)
leucine-rich repeat 115..138 CDD:275380 5/22 (23%)
leucine-rich repeat 139..160 CDD:275380 5/22 (23%)
leucine-rich repeat 161..184 CDD:275380 5/26 (19%)
LRR_8 183..244 CDD:290566 18/60 (30%)
leucine-rich repeat 185..209 CDD:275380 6/23 (26%)
LRR_4 209..247 CDD:289563 13/37 (35%)
leucine-rich repeat 210..233 CDD:275380 6/22 (27%)
leucine-rich repeat 234..259 CDD:275380 9/24 (38%)
LRR_RI 250..492 CDD:238064 62/249 (25%)
LRR_8 259..318 CDD:290566 18/59 (31%)
leucine-rich repeat 260..283 CDD:275380 9/23 (39%)
leucine-rich repeat 284..307 CDD:275380 5/22 (23%)
leucine-rich repeat 308..359 CDD:275380 8/50 (16%)
leucine-rich repeat 334..348 CDD:275378 0/13 (0%)
LRR_8 358..418 CDD:290566 16/60 (27%)
leucine-rich repeat 360..383 CDD:275380 9/23 (39%)
leucine-rich repeat 384..407 CDD:275380 4/22 (18%)
LRR_8 406..466 CDD:290566 14/60 (23%)
leucine-rich repeat 408..431 CDD:275380 4/22 (18%)
leucine-rich repeat 432..455 CDD:275380 5/23 (22%)
LRR_RI 447..705 CDD:238064 20/101 (20%)
LRR_8 454..514 CDD:290566 16/64 (25%)
leucine-rich repeat 456..476 CDD:275380 8/24 (33%)
leucine-rich repeat 480..501 CDD:275380 5/20 (25%)
leucine-rich repeat 505..517 CDD:275378 1/11 (9%)
leucine-rich repeat 525..550 CDD:275380 3/17 (18%)
LRR_8 549..609 CDD:290566
leucine-rich repeat 551..574 CDD:275380
leucine-rich repeat 575..598 CDD:275380
leucine-rich repeat 599..622 CDD:275380
LRR_8 622..681 CDD:290566
leucine-rich repeat 623..646 CDD:275380
LRR_RI 647..896 CDD:238064
leucine-rich repeat 647..670 CDD:275380
leucine-rich repeat 671..693 CDD:275380
leucine-rich repeat 694..717 CDD:275380
LRR_8 716..776 CDD:290566
leucine-rich repeat 718..741 CDD:275380
leucine-rich repeat 742..763 CDD:275380
LRR_8 765..824 CDD:290566
leucine-rich repeat 766..789 CDD:275380
leucine-rich repeat 790..813 CDD:275380
leucine-rich repeat 814..835 CDD:275380
leucine-rich repeat 838..861 CDD:275380
LRR_8 862..921 CDD:290566
leucine-rich repeat 862..885 CDD:275380
leucine-rich repeat 886..906 CDD:275380
TPKR_C2 919..>946 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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