DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14762 and conv

DIOPT Version :9

Sequence 1:	NP_001246198.1	Gene:	CG14762 / 35768	FlyBaseID:	FBgn0033250	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	128/460 - (27%)
Similarity:	213/460 - (46%)	Gaps:	70/460 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 ETTDLA--HITK-SMGTLKGKSPIIFYLKLRHNNLPKLQGFVF------LALDIRHLTIHNSSLA 117
            |..|||  :||| ...:.|.....|  :.:.||.|..::...|      ..||:.|..:.|.|..
  Fly   345 ELLDLAENNITKIEKNSFKDIYQAI--INVSHNALELIETAAFENCVNITVLDLSHNRLANFSRR 407

  Fly   118 AIEE-----------NALSSLG-------AGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNK 164
            :.:|           |.|::|.       .||..|:.|.|.:..:|......|:.|..::::||.
  Fly   408 SFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNN 472

  Fly   165 ITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLK 229
            |:.|.|..|:.|.:|..:.|..|.:.:|....| |....:..::|..|:|.::.:.:|:.|::|:
  Fly   473 ISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTF-GTLPTLLEMDLSHNELVSVVRGSLAKLTSLR 536

  Fly   230 KLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKI-SVIDKDA 293
            :|.:..|::..:    |:...||:.|..:||.:|.:|:..:..:..|..|:|..|:: ..::.::
  Fly   537 QLYLNNNQLEKL----FQLPISLNELYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGES 597

  Fly   294 FKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKN 358
            |.||.. :|.|:|.:|.|...|.:|:..:..|::|.|.||||..|...|| |....|..|||..|
  Fly   598 FTGLLV-VQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAF-GKLPVLFELNLYGN 660

  Fly   359 DIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPKLLE 423
            .:|.:....||.|..|.||||.:|.:|.:..||... :.:||.:|::.|.|.
  Fly   661 QVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVG-LPSLRNLDLSFNSLT------------- 711

  Fly   424 DLKNK-----DDEMSQKKKPLCHMSLDNREYFV--QAMPTEK---MHCAGLNVSPSPTSGGLMRI 478
            .|.||     ||.:|.:...|.|    ||..||  :..|:.:   .:...||:|.:     ||.|
  Fly   712 KLDNKTNGVLDDLLSLETLDLSH----NRISFVTKKTFPSHQYIPYNLRNLNLSYN-----LMPI 767

  Fly   479 LQVNI 483
            |..:|
  Fly   768 LTYDI 772

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	4/25 (16%)
		LRR_RI	93..384	CDD:238064	88/315 (28%)
		leucine-rich repeat	107..129	CDD:275380	7/39 (18%)
		leucine-rich repeat	131..154	CDD:275380	6/22 (27%)
		LRR_8	154..214	CDD:290566	16/59 (27%)
		leucine-rich repeat	155..178	CDD:275380	8/22 (36%)
		leucine-rich repeat	179..203	CDD:275380	6/23 (26%)
		leucine-rich repeat	204..227	CDD:275380	5/22 (23%)
		LRR_8	226..286	CDD:290566	15/59 (25%)
		leucine-rich repeat	228..251	CDD:275380	4/22 (18%)
		leucine-rich repeat	252..275	CDD:275380	6/22 (27%)
		LRR_8	276..335	CDD:290566	19/59 (32%)
		leucine-rich repeat	276..300	CDD:275380	7/24 (29%)
		leucine-rich repeat	301..324	CDD:275380	7/22 (32%)
		leucine-rich repeat	325..349	CDD:275380	11/23 (48%)
		LRR_8	349..409	CDD:290566	22/59 (37%)
		leucine-rich repeat	350..373	CDD:275380	9/22 (41%)
conv	NP_001286416.1	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		LRR_8	198..258	CDD:290566
		leucine-rich repeat	200..223	CDD:275380
		LRR_RI	201..545	CDD:238064	51/202 (25%)
		leucine-rich repeat	224..271	CDD:275380
		LRR_8	245..306	CDD:290566
		leucine-rich repeat	272..295	CDD:275380
		LRR_8	296..354	CDD:290566	4/8 (50%)
		leucine-rich repeat	296..319	CDD:275380
		LRR_8	322..401	CDD:290566	16/57 (28%)
		leucine-rich repeat	322..343	CDD:275380
		leucine-rich repeat	344..367	CDD:275380	8/21 (38%)
		leucine-rich repeat	371..390	CDD:275380	4/18 (22%)
		leucine-rich repeat	391..414	CDD:275380	6/22 (27%)
		leucine-rich repeat	416..438	CDD:275380	3/21 (14%)
		LRR_8	437..495	CDD:290566	17/57 (30%)
		leucine-rich repeat	439..462	CDD:275380	6/22 (27%)
		leucine-rich repeat	463..486	CDD:275380	8/22 (36%)
		LRR_RI	486..738	CDD:238064	80/276 (29%)
		LRR_8	486..545	CDD:290566	14/59 (24%)
		leucine-rich repeat	487..510	CDD:275380	6/23 (26%)
		leucine-rich repeat	511..534	CDD:275380	5/22 (23%)
		leucine-rich repeat	535..554	CDD:275380	4/22 (18%)
		LRR_8	554..614	CDD:290566	18/60 (30%)
		leucine-rich repeat	555..578	CDD:275380	6/22 (27%)
		leucine-rich repeat	579..603	CDD:275380	7/23 (30%)
		leucine-rich repeat	604..627	CDD:275380	7/22 (32%)
		LRR_8	626..710	CDD:290566	33/85 (39%)
		leucine-rich repeat	628..649	CDD:275380	11/21 (52%)
		leucine-rich repeat	652..672	CDD:275380	7/19 (37%)
		LRR_8	698..765	CDD:290566	21/88 (24%)
		leucine-rich repeat	700..726	CDD:275380	10/38 (26%)
		leucine-rich repeat	727..745	CDD:275380	6/21 (29%)
		LRR_8	777..839	CDD:290566
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010