Protein Alignment CG14762 and CG42346

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001036303.2
• Gene: CG42346 / 3355160
• FlyBaseID: FBgn0259677
• Length: 1817
• Species: Drosophila melanogaster
• Alignment Length: 480
• Identity: 122/480 - (25%)
• Similarity: 196/480 - (40%)
• Gaps: 109/480 - (22%)

  Fly    86 LKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQ 150
            |...:|.:.::..:.|..|.|..|.:..:.|..:.|:|.:.|...:.::|||.|.::|.|..||:
  Fly   354 LDFDYNEIVRVDDYSFYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALR 418

  Fly   151 HLFHLLILNLNHNKITVIH-------NNA--------------------------------FEGL 176
            .|.||.||.|::|:|...:       |||                                |...
  Fly   419 KLDHLRILRLSNNRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRAF 483

  Fly   177 ETLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTI 241
            ..|:.|:.|.|:|..:.||||:.|.: :..|::..|.:..:..|.......|:.:::..|.|.||
  Fly   484 PQLKTLSFYANQIELVQPEAFKSLRE-LMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTI 547

  Fly   242 SEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQ--YL 304
            . |.|..|..|..:.|:.|.|..:||:.|::.|.::.:.||.|.|:.||.:.|..| .||.  ||
  Fly   548 G-GVFSNLPQLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTL-VNLDHLYL 610

  Fly   305 R----------------------LGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFG 347
            |                      |.:|:|..:.....|.|..||.:.|.||.|..:....|...
  Fly   611 RSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPL- 674

  Fly   348 DSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTL------------- 399
            .||..|::|||.|:.:....|..|.:::.:|||:|:| .:.:||......:|
  Fly   675 PSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQL-TVLEDIFPDENSSLLSVQLEANYLHKV 738

  Fly   400 -----------RIIDITDNPLNCSCELTWF---PKL----LEDLKNKDDEMSQKKKPLCHMSLD- 445
                       :|:.:.||.|. ..|.::|   |:|    |.|.|.:|.|.......|....||
  Fly   739 HPRTFSRQQKVQIMWLKDNQLT-RVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDL 802

  Fly   446 --------NREYFVQAMPTEKMHCA 462
                    .|:||......|::..|
  Fly   803 SGNQLRQLRRDYFAPLQDLEELSLA 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	3/18 (17%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		LRR	<131..410	CDD:443914	94/365 (26%)
		leucine-rich repeat	131..154	CDD:275380	9/22 (41%)
		leucine-rich repeat	155..178	CDD:275380	10/61 (16%)
		leucine-rich repeat	179..203	CDD:275380	10/23 (43%)
		leucine-rich repeat	204..227	CDD:275380	3/22 (14%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)
		leucine-rich repeat	276..300	CDD:275380	8/23 (35%)
		leucine-rich repeat	301..324	CDD:275380	9/46 (20%)
		leucine-rich repeat	325..349	CDD:275380	7/23 (30%)
		leucine-rich repeat	350..373	CDD:275380	8/22 (36%)
CG42346	NP_001036303.2	LRR	<301..606	CDD:443914	68/254 (27%)
		leucine-rich repeat	303..325	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	351..461	CDD:275380	29/106 (27%)
		leucine-rich repeat	399..422	CDD:275380	9/22 (41%)
		leucine-rich repeat	462..485	CDD:275380	1/22 (5%)
		LRR	486..>736	CDD:443914	71/254 (28%)
		leucine-rich repeat	486..509	CDD:275380	10/22 (45%)
		leucine-rich repeat	510..533	CDD:275380	3/22 (14%)
		leucine-rich repeat	534..556	CDD:275380	8/22 (36%)
		leucine-rich repeat	557..580	CDD:275380	7/22 (32%)
		leucine-rich repeat	581..604	CDD:275380	8/23 (35%)
		leucine-rich repeat	605..628	CDD:275380	4/22 (18%)
		PPP1R42	627..860	CDD:455733	50/204 (25%)
		leucine-rich repeat	629..652	CDD:275380	5/22 (23%)
		leucine-rich repeat	653..676	CDD:275380	7/23 (30%)
		leucine-rich repeat	677..700	CDD:275380	8/22 (36%)
		leucine-rich repeat	701..748	CDD:275380	8/47 (17%)
		leucine-rich repeat	725..736	CDD:275378	1/10 (10%)
		leucine-rich repeat	749..772	CDD:275380	6/23 (26%)
		leucine-rich repeat	773..793	CDD:275380	6/19 (32%)
		leucine-rich repeat	821..844	CDD:275380	2/7 (29%)
		leucine-rich repeat	845..868	CDD:275380
		LRR	869..1226	CDD:443914
		leucine-rich repeat	869..892	CDD:275380
		leucine-rich repeat	893..915	CDD:275380
		leucine-rich repeat	916..944	CDD:275380
		leucine-rich repeat	945..968	CDD:275380
		leucine-rich repeat	969..992	CDD:275380
		leucine-rich repeat	993..1014	CDD:275380
		leucine-rich repeat	1017..1040	CDD:275380
		leucine-rich repeat	1041..1064	CDD:275380
		leucine-rich repeat	1089..1114	CDD:275380
		leucine-rich repeat	1115..1162	CDD:275380
		PPP1R42	1155..1317	CDD:455733
		leucine-rich repeat	1163..1186	CDD:275380
		leucine-rich repeat	1187..1210	CDD:275380
		leucine-rich repeat	1211..1233	CDD:275380
		leucine-rich repeat	1234..1257	CDD:275380
		leucine-rich repeat	1258..1279	CDD:275380
		leucine-rich repeat	1282..1306	CDD:275380