Protein Alignment CG14762 and Tlr13

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001395788.1
• Gene: Tlr13 / 317227
• RGDID: 1562655
• Length: 956
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 139/514 - (27%)
• Similarity: 223/514 - (43%)
• Gaps: 124/514 - (24%)

  Fly    54 KNG---LDILCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTI---H 112
            |:|   :.|:|      ::.:::..|:    |:|:    |.|....:|...||...|.|.:   .
  Rat   295 KHGHLNMKIVC------YLLRNLPMLE----ILFF----HKNATNAEGIKQLAKCTRLLFLDLGQ 345

  Fly   113 NSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLE 177
            ||.|..:.::..::| ..|.:|:::..|:..:.::....|.:|.||:|:|||.....:.||..|:
  Rat   346 NSDLVHLNDSEFNAL-PSLQRLNLNKCQLSFISNKTWSSLQNLTILDLSHNKFKSFPDFAFSPLK 409

  Fly   178 TLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTIS 242
            .||.|:|..|.||:::..||.||.. :|.|||....:..|.:.:.:....|:.|::.:|.|||::
  Rat   410 RLEFLSLSRNPITELNNLAFSGLFS-LKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLN 473

  Fly   243 EGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLG 307
            .|.|:.|:.|.:|||:||.:..:.:|.||.||.|..|:|..|.:|...|..|.|||: |..|:||
  Rat   474 HGTFQPLKKLHTLILSHNRLEIMESNAFSGLTGLRYLDLMYNSLSYFHKHHFMGLEK-LLVLKLG 537

  Fly   308 DNQI-----HTIPSEALRPLHRLRHLDL--RNNNINVLAEDAFTG---------------FGDSL 350
            .|:|     .|:.......|..|:.|:|  :.:.|.|:..:.|.|               |.|..
  Rat   538 FNKITYETTRTLQYPPFMKLKSLKQLNLEGQKHGIQVVPRNFFQGLSSLQELLLGKNPSVFLDHH 602

  Fly   351 TF---LNLQKNDIK---------VLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPV-------- 395
            .|   :||.|.||.         .|.|.||:||..|:.|.|:||.|:.:...:...:
  Rat   603 QFDPLINLTKLDISGTKDGDRSLYLNSSLFQNLKRLKVLRLENNNLESLVPGMFSSLQNLQVFSL 667

  Fly   396 ---------------IDTLRIIDITDNPLNCSCELTWFPKLLEDLKNKDDEMSQKKKPLCHMSLD 445
                           :.:|...|:..|.|.|:|:..||       ||
  Rat   668 RFNNLKVINQSHLENLKSLMFFDVYGNKLQCTCDNLWF-------KN------------------ 707

  Fly   446 NREYFVQAMPTEKMHCAGLNVSP--SPTSGGLMRILQVNILAQIAVCS-----VAFLTS 497
                  .:|.||::|...|...|  .|.|..|:      |....|:|:     |.||.|
  Rat   708 ------WSMNTEEVHIPFLRSYPCQQPNSQSLL------IDFDDAMCNFDLGKVYFLCS 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	5/19 (26%)
		leucine-rich repeat	107..129	CDD:275380	6/24 (25%)
		LRR	<131..410	CDD:443914	98/335 (29%)
		leucine-rich repeat	131..154	CDD:275380	4/22 (18%)
		leucine-rich repeat	155..178	CDD:275380	10/22 (45%)
		leucine-rich repeat	179..203	CDD:275380	11/23 (48%)
		leucine-rich repeat	204..227	CDD:275380	5/22 (23%)
		leucine-rich repeat	228..251	CDD:275380	9/22 (41%)
		leucine-rich repeat	252..275	CDD:275380	10/22 (45%)
		leucine-rich repeat	276..300	CDD:275380	10/23 (43%)
		leucine-rich repeat	301..324	CDD:275380	8/27 (30%)
		leucine-rich repeat	325..349	CDD:275380	8/40 (20%)
		leucine-rich repeat	350..373	CDD:275380	12/34 (35%)
Tlr13	NP_001395788.1	leucine-rich repeat	47..69	CDD:275380
		LRR	54..435	CDD:443914	43/155 (28%)
		leucine-rich repeat	70..93	CDD:275380
		leucine-rich repeat	94..117	CDD:275380
		leucine-rich repeat	118..140	CDD:275380
		leucine-rich repeat	141..164	CDD:275380
		leucine-rich repeat	165..190	CDD:275380
		leucine-rich repeat	191..213	CDD:275380
		leucine-rich repeat	214..236	CDD:275380
		leucine-rich repeat	237..260	CDD:275380
		leucine-rich repeat	261..283	CDD:275380
		LRR	299..697	CDD:443914	114/414 (28%)
		leucine-rich repeat	338..362	CDD:275380	5/24 (21%)
		leucine-rich repeat	363..386	CDD:275380	4/22 (18%)
		leucine-rich repeat	387..410	CDD:275380	10/22 (45%)
		leucine-rich repeat	411..434	CDD:275380	11/22 (50%)
		leucine-rich repeat	435..458	CDD:275380	5/22 (23%)
		leucine-rich repeat	459..482	CDD:275380	9/22 (41%)
		leucine-rich repeat	483..506	CDD:275380	10/22 (45%)
		leucine-rich repeat	507..530	CDD:275380	9/22 (41%)
		leucine-rich repeat	531..585	CDD:275380	15/53 (28%)
		leucine-rich repeat	638..661	CDD:275380	6/22 (27%)
		leucine-rich repeat	662..683	CDD:275380	0/20 (0%)
		TIR	799..943	CDD:214587