Protein Alignment CG14762 and Lrrtm3

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001099857.1
• Gene: Lrrtm3 / 294380
• RGDID: 1304866
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 471
• Identity: 119/471 - (25%)
• Similarity: 189/471 - (40%)
• Gaps: 128/471 - (27%)

  Fly     8 SGCTMVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKS 72
            |...:|:...:||.:|...:         :.||:     .|.|    .|..:.||:..|..|..|
  Rat    12 SAVAVVLAPTVLLTMLSSAE---------RGCPK-----GCRC----EGKMVYCESQKLQEIPSS 58

  Fly    73 M--GTLKGKSPIIFYLKLRHNNLPKLQGFVFLALD-IRHLTIHNSSLAAIEENALSSLGAGLTQL 134
            :  |.|.        |.||:|:|.||:...|..|: :..|.:.::.::.|:|||.:.:
  Rat    59 ISAGCLG--------LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGI------- 108

  Fly   135 DVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRG 199
                        :.|:.|.      |:.|:|:...||.|..:..|..|.|..|::..:..|.|||
  Rat   109 ------------RRLKELI------LSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRG 155

  Fly   200 LEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITT 264
            |. .:..|:|..|.|..||.:.......|:.|::..|:||:::...|.|:..|..|.|.||..:.
  Rat   156 LR-KLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSK 219

  Fly   265 VPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLD 329
            :...:|..|..|.:|.::.||||||                 |.....|..|        |:.||
  Rat   220 LNLALFPRLVSLQNLYMQWNKISVI-----------------GQTMSWTWSS--------LQRLD 259

  Fly   330 LRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEP 394
            |..|.|     :||:|                  || :|:.:.:|:.|||.:|||..|.|:|::.
  Rat   260 LSGNEI-----EAFSG------------------PS-VFQCVPNLQRLNLDSNKLTFIGQEILDS 300

  Fly   395 VIDTLRIIDITDNPLNCS---CEL-TWF---------------PKLLEDLKNKDDEMSQKKKPLC 440
            .| :|..|.:..|...||   |.| .|.               ||.|:.:...|   :.|...:|
  Rat   301 WI-SLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTILCASPKELQGVNVID---AVKNYSIC 361

  Fly   441 HMSLDNREY-FVQAMP 455
            ..|.....: ..:|:|
  Rat   362 GKSTTTERFDLARALP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	8/19 (42%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		LRR	<131..410	CDD:443914	74/278 (27%)
		leucine-rich repeat	131..154	CDD:275380	2/22 (9%)
		leucine-rich repeat	155..178	CDD:275380	6/22 (27%)
		leucine-rich repeat	179..203	CDD:275380	9/23 (39%)
		leucine-rich repeat	204..227	CDD:275380	6/22 (27%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)
		leucine-rich repeat	276..300	CDD:275380	8/23 (35%)
		leucine-rich repeat	301..324	CDD:275380	3/22 (14%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	3/22 (14%)
Lrrtm3	NP_001099857.1	LRRNT	33..61	CDD:214470	10/36 (28%)
		LRR	59..339	CDD:443914	95/363 (26%)
		LRR 1	61..83		10/29 (34%)
		leucine-rich repeat	66..86	CDD:275380	9/19 (47%)
		LRR 2	84..107		6/22 (27%)
		leucine-rich repeat	87..110	CDD:275380	5/41 (12%)
		LRR 3	109..131		8/27 (30%)
		leucine-rich repeat	111..134	CDD:275380	8/28 (29%)
		LRR 4	132..155		6/22 (27%)
		leucine-rich repeat	135..158	CDD:275380	9/23 (39%)
		LRR 5	156..179		7/23 (30%)
		leucine-rich repeat	159..182	CDD:275380	6/22 (27%)
		LRR 6	181..203		6/21 (29%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		LRR 7	205..227		6/21 (29%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		LRR 8	229..251		9/38 (24%)
		leucine-rich repeat	231..254	CDD:275380	10/39 (26%)
		LRR 9	252..276		13/55 (24%)
		leucine-rich repeat	255..279	CDD:275380	12/47 (26%)
		LRR 10	277..300		10/22 (45%)
		leucine-rich repeat	280..300	CDD:275380	10/19 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..411		119/471 (25%)