Protein Alignment CG14762 and Lrfn3

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_780687.1
• Gene: Lrfn3 / 233067
• MGIID: 2442512
• Length: 626
• Species: Mus musculus
• Alignment Length: 246
• Identity: 69/246 - (28%)
• Similarity: 116/246 - (47%)
• Gaps: 29/246 - (11%)

  Fly   230 KLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAF 294
            :|.:.:|.|..:...|...:..|..|.|:.|.|..|.|..|:.|..|.:|.|:||:::.:.:...
Mouse    63 ELRLADNFIAAVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQL 127

  Fly   295 KGLEENLQYLRLGDNQIHTIPSEALRP-LHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKN 358
            :|| .||::|.|.:||:..:.:.||.. ...|..|||..||:..|..:|....|:..| |.|..|
Mouse   128 RGL-VNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNT-LGLDHN 190

  Fly   359 DIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTL-------------RIIDITDNPLN 410
            .:..:|:..|..|:.|..|::.:|:|..||.|   |:...|             .::....|||:
Mouse   191 LLASVPAGAFSRLHKLARLDMTSNRLTTIPPD---PLFSRLPLLARPRGSPASALVLAFGGNPLH 252

  Fly   411 CSCELTWFPKLLEDLKNKDDEMSQKKKPLCHMSLDNREYFVQAMPTEKMHC 461
            |:|||.|..:|.     ::|::.....|   .:|..|.::  |:..|:..|
Mouse   253 CNCELVWLRRLA-----REDDLEACASP---PALGGRYFW--AVGEEEFVC 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		leucine-rich repeat	107..129	CDD:275380
		LRR	<131..410	CDD:443914	55/193 (28%)
		leucine-rich repeat	131..154	CDD:275380
		leucine-rich repeat	155..178	CDD:275380
		leucine-rich repeat	179..203	CDD:275380
		leucine-rich repeat	204..227	CDD:275380
		leucine-rich repeat	228..251	CDD:275380	4/20 (20%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		leucine-rich repeat	276..300	CDD:275380	7/23 (30%)
		leucine-rich repeat	301..324	CDD:275380	7/23 (30%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	7/22 (32%)
Lrfn3	NP_780687.1	leucine-rich repeat	63..84	CDD:275380	4/20 (20%)
		LRR	<78..>228	CDD:443914	49/154 (32%)
		LRR 1	84..105		8/20 (40%)
		leucine-rich repeat	85..108	CDD:275380	9/22 (41%)
		LRR 2	108..129		5/20 (25%)
		leucine-rich repeat	109..132	CDD:275380	7/23 (30%)
		LRR 3	132..153		8/20 (40%)
		leucine-rich repeat	133..157	CDD:275380	7/23 (30%)
		LRR 4	157..178		8/20 (40%)
		leucine-rich repeat	158..181	CDD:275380	8/22 (36%)
		LRR 5	181..202		6/21 (29%)
		leucine-rich repeat	182..205	CDD:275380	7/23 (30%)
		LRR 6	205..226		8/23 (35%)
		leucine-rich repeat	206..230	CDD:275380	9/26 (35%)
		leucine-rich repeat	242..253	CDD:275378	3/10 (30%)
		LRRCT	249..>281	CDD:214507	12/39 (31%)
		Ig	296..383	CDD:472250
		Ig strand B	313..317	CDD:409353
		Ig strand C	326..330	CDD:409353
		Ig strand E	349..353	CDD:409353
		Ig strand F	363..368	CDD:409353
		Ig strand G	376..379	CDD:409353
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..425
		fn3	425..502	CDD:394996
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	590..626