Protein Alignment CG14762 and Lrfn3

DIOPT Version :9

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_780687.1
• Gene: Lrfn3 / 233067
• MGIID: 2442512
• Length: 626
• Species: Mus musculus
• Alignment Length: 246
• Identity: 69/246 - (28%)
• Similarity: 116/246 - (47%)
• Gaps: 29/246 - (11%)

  Fly   230 KLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAF 294
            :|.:.:|.|..:...|...:..|..|.|:.|.|..|.|..|:.|..|.:|.|:||:::.:.:...
Mouse    63 ELRLADNFIAAVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQL 127

  Fly   295 KGLEENLQYLRLGDNQIHTIPSEALRP-LHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKN 358
            :|| .||::|.|.:||:..:.:.||.. ...|..|||..||:..|..:|....|:..| |.|..|
Mouse   128 RGL-VNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNT-LGLDHN 190

  Fly   359 DIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTL-------------RIIDITDNPLN 410
            .:..:|:..|..|:.|..|::.:|:|..||.|   |:...|             .::....|||:
Mouse   191 LLASVPAGAFSRLHKLARLDMTSNRLTTIPPD---PLFSRLPLLARPRGSPASALVLAFGGNPLH 252

  Fly   411 CSCELTWFPKLLEDLKNKDDEMSQKKKPLCHMSLDNREYFVQAMPTEKMHC 461
            |:|||.|..:|.     ::|::.....|   .:|..|.::  |:..|:..|
Mouse   253 CNCELVWLRRLA-----REDDLEACASP---PALGGRYFW--AVGEEEFVC 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		LRR_RI	93..384	CDD:238064	47/154 (31%)
		leucine-rich repeat	107..129	CDD:275380
		leucine-rich repeat	131..154	CDD:275380
		LRR_8	154..214	CDD:290566
		leucine-rich repeat	155..178	CDD:275380
		leucine-rich repeat	179..203	CDD:275380
		leucine-rich repeat	204..227	CDD:275380
		LRR_8	226..286	CDD:290566	18/55 (33%)
		leucine-rich repeat	228..251	CDD:275380	4/20 (20%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		LRR_8	276..335	CDD:290566	20/59 (34%)
		leucine-rich repeat	276..300	CDD:275380	7/23 (30%)
		leucine-rich repeat	301..324	CDD:275380	7/23 (30%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		LRR_8	349..409	CDD:290566	17/72 (24%)
		leucine-rich repeat	350..373	CDD:275380	7/22 (32%)
Lrfn3	NP_780687.1	LRR	<63..>222	CDD:227223	50/160 (31%)
		leucine-rich repeat	63..84	CDD:275380	4/20 (20%)
		LRR 1	84..105		8/20 (40%)
		leucine-rich repeat	85..108	CDD:275380	9/22 (41%)
		LRR 2	108..129		5/20 (25%)
		leucine-rich repeat	109..132	CDD:275380	7/23 (30%)
		LRR 3	132..153		8/20 (40%)
		leucine-rich repeat	133..157	CDD:275380	7/23 (30%)
		LRR 4	157..178		8/20 (40%)
		leucine-rich repeat	158..181	CDD:275380	8/22 (36%)
		LRR 5	181..202		6/21 (29%)
		leucine-rich repeat	182..205	CDD:275380	7/23 (30%)
		LRR 6	205..226		8/23 (35%)
		leucine-rich repeat	206..230	CDD:275380	9/26 (35%)
		leucine-rich repeat	242..253	CDD:275378	3/10 (30%)
		TPKR_C2	249..>281	CDD:326558	12/39 (31%)
		Ig	310..383	CDD:325142
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..425
		fn3	425..502	CDD:306538
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	590..626

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910