Protein Alignment CG14762 and Lrrc66

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_705796.1
• Gene: Lrrc66 / 231296
• MGIID: 2387634
• Length: 872
• Species: Mus musculus
• Alignment Length: 308
• Identity: 70/308 - (22%)
• Similarity: 113/308 - (36%)
• Gaps: 79/308 - (25%)

  Fly   109 LTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAF 173
            |.::.||:..:.:|.        ..:|.|....:.:.....|...|:...:..|::|:.:..:..
Mouse    42 LLVNWSSIRHVSQNT--------DAMDRSFYFFRVLFQPHTQKERHIKPPDRTHHRISKVTLDPL 98

  Fly   174 EGLETLEILTLYENKITQIDPEAFRGLEDHIKR--------------LNLGGNDLTNIPQKALSI 224
            ..|..||||.|....|.....:.......|.||              |.|..|.|:..| |.|..
Mouse    99 AHLHALEILNLSNKAIHYFSLDQPLPPSSHQKRHGGHSHSRLPRLQVLILQRNQLSGTP-KGLWK 162

  Fly   225 LSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVI 289
            |.:|:.|::..|:|..|...||.|...|:|:.|..|.|.|:....|..|..|..::|..|.::.:
Mouse   163 LKSLRSLDLSFNRIVHIGLSDFHGCLQLESIYLKSNKICTIHPKAFKGLKKLQVVDLRSNALTTL 227

  Fly   290 DKDAFKGLEENLQYLRLG--DNQ---------IHTIPSEALRPL------------------HRL 325
            .......||  |.:|.||  |||         ...|.|.:.|.:                  |::
Mouse   228 VPIVTIALE--LPHLELGLADNQWQCSESNVNFQNITSSSWREIWKAICNMSVENKRPNAETHQI 290

  Fly   326 R-----HL------DLR--------------NNNINVLAEDAFTGFGD 348
            |     ||      ||:              :.:::.|.::|..|:||
Mouse   291 RKSRDTHLLLSPPSDLKSLIQSKAERPQAGMDMHLSALGKEAKDGYGD 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		leucine-rich repeat	107..129	CDD:275380	4/19 (21%)
		LRR	<131..410	CDD:443914	66/286 (23%)
		leucine-rich repeat	131..154	CDD:275380	3/22 (14%)
		leucine-rich repeat	155..178	CDD:275380	3/22 (14%)
		leucine-rich repeat	179..203	CDD:275380	6/23 (26%)
		leucine-rich repeat	204..227	CDD:275380	10/36 (28%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	8/22 (36%)
		leucine-rich repeat	276..300	CDD:275380	5/23 (22%)
		leucine-rich repeat	301..324	CDD:275380	10/51 (20%)
		leucine-rich repeat	325..349	CDD:275380	10/49 (20%)
		leucine-rich repeat	350..373	CDD:275380
Lrrc66	NP_705796.1	LRR	<98..>263	CDD:443914	47/167 (28%)
		leucine-rich repeat	104..142	CDD:275380	9/37 (24%)
		LRR 1	142..164		7/22 (32%)
		leucine-rich repeat	143..165	CDD:275380	8/22 (36%)
		LRR 2	165..186		7/20 (35%)
		leucine-rich repeat	166..189	CDD:275380	8/22 (36%)
		LRR 3	189..210		7/20 (35%)
		leucine-rich repeat	190..213	CDD:275380	8/22 (36%)
		LRR 4	213..234		3/20 (15%)
		LRR 5	239..259		6/19 (32%)
		leucine-rich repeat	240..263	CDD:275380	7/22 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	339..363		70/308 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	467..501
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	560..579
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	695..761
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	776..872