Protein Alignment CG14762 and Lrfn4

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_700437.2
• Gene: Lrfn4 / 225875
• MGIID: 2385612
• Length: 636
• Species: Mus musculus
• Alignment Length: 244
• Identity: 73/244 - (29%)
• Similarity: 114/244 - (46%)
• Gaps: 29/244 - (11%)

  Fly   230 KLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAF 294
            :|.:.:|.|:.:...||..:..|..|.|:.|.||.:.|..|..|..|.||.|:||::..:...:.
Mouse    52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSL 116

  Fly   295 KGLEENLQYLRLGDNQIHTIPSEALRP-LHRLRHLDLRNNNINVLAEDAFTGFGD--SLTFLNLQ 356
            :| ..|||:|.|..||:..|...|... |..|..||:..||   |.:..:.|.|.  :|..|||.
Mouse   117 RG-PVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNN---LRQVPWAGIGSMPALHTLNLD 177

  Fly   357 KNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLR---------IIDITDNPLNCS 412
            .|.|..||..:|..|:.|..|:|.:|:|..:..|   |:....|         ::..:.|||:|:
Mouse   178 HNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPD---PLFSRGRDAEASPSPLVLSFSGNPLHCN 239

  Fly   413 CELTWFPKLLEDLKNKDDEMSQKKKPLCHMSLDNREYFVQAMPTEKMHC 461
            |||.|..:|.     :.|::.....|   .:|..|.::  |:|..:..|
Mouse   240 CELLWLRRLA-----RPDDLETCASP---PTLAGRYFW--AVPEGEFSC 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		leucine-rich repeat	107..129	CDD:275380
		LRR	<131..410	CDD:443914	59/191 (31%)
		leucine-rich repeat	131..154	CDD:275380
		leucine-rich repeat	155..178	CDD:275380
		leucine-rich repeat	179..203	CDD:275380
		leucine-rich repeat	204..227	CDD:275380
		leucine-rich repeat	228..251	CDD:275380	5/20 (25%)
		leucine-rich repeat	252..275	CDD:275380	9/22 (41%)
		leucine-rich repeat	276..300	CDD:275380	7/23 (30%)
		leucine-rich repeat	301..324	CDD:275380	9/23 (39%)
		leucine-rich repeat	325..349	CDD:275380	8/25 (32%)
		leucine-rich repeat	350..373	CDD:275380	10/22 (45%)
Lrfn4	NP_700437.2	LRR 1	49..70		5/17 (29%)
		leucine-rich repeat	50..73	CDD:275380	5/20 (25%)
		LRR	<52..>210	CDD:443914	54/161 (34%)
		LRR 2	73..94		8/20 (40%)
		leucine-rich repeat	74..97	CDD:275380	9/22 (41%)
		LRR 3	97..118		6/20 (30%)
		leucine-rich repeat	98..121	CDD:275380	7/23 (30%)
		LRR 4	121..142		9/20 (45%)
		leucine-rich repeat	122..146	CDD:275380	9/23 (39%)
		LRR 5	146..169		8/25 (32%)
		leucine-rich repeat	147..170	CDD:275380	8/25 (32%)
		LRR 6	170..191		9/20 (45%)
		leucine-rich repeat	171..194	CDD:275380	10/22 (45%)
		LRR 7	194..215		7/23 (30%)
		leucine-rich repeat	195..213	CDD:275380	6/20 (30%)
		LRRCT	234..278	CDD:214507	15/53 (28%)
		Ig	281..368	CDD:472250
		Ig strand B	298..302	CDD:409353
		Ig strand C	311..315	CDD:409353
		Ig strand E	334..338	CDD:409353
		Ig strand F	348..353	CDD:409353
		Ig strand G	361..364	CDD:409353
		fn3	409..478	CDD:394996
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	556..585
		PDZ-binding	633..636