Protein Alignment CG14762 and Lrrtm3

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_848793.1
• Gene: Lrrtm3 / 216028
• MGIID: 2389177
• Length: 582
• Species: Mus musculus
• Alignment Length: 471
• Identity: 119/471 - (25%)
• Similarity: 189/471 - (40%)
• Gaps: 128/471 - (27%)

  Fly     8 SGCTMVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKS 72
            |...:|:...:||.:|...:         :.||:     .|.|    .|..:.||:..|..|..|
Mouse    12 SAVAVVLAPTVLLTMLSSAE---------RGCPK-----GCRC----EGKMVYCESQKLQEIPSS 58

  Fly    73 M--GTLKGKSPIIFYLKLRHNNLPKLQGFVFLALD-IRHLTIHNSSLAAIEENALSSLGAGLTQL 134
            :  |.|.        |.||:|:|.||:...|..|: :..|.:.::.::.|:|||.:.:
Mouse    59 ISAGCLG--------LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGI------- 108

  Fly   135 DVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRG 199
                        :.|:.|.      |:.|:|:...||.|..:..|..|.|..|::..:..|.|||
Mouse   109 ------------RRLKELI------LSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRG 155

  Fly   200 LEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITT 264
            |. .:..|:|..|.|..||.:.......|:.|::..|:||:::...|.|:..|..|.|.||..:.
Mouse   156 LR-KLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSK 219

  Fly   265 VPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLD 329
            :...:|..|..|.:|.::.||||||                 |.....|..|        |:.||
Mouse   220 LNLALFPRLVSLQNLYMQWNKISVI-----------------GQTMSWTWSS--------LQRLD 259

  Fly   330 LRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEP 394
            |..|.|     :||:|                  || :|:.:.:|:.|||.:|||..|.|:|::.
Mouse   260 LSGNEI-----EAFSG------------------PS-VFQCVPNLQRLNLDSNKLTFIGQEILDS 300

  Fly   395 VIDTLRIIDITDNPLNCS---CEL-TWF---------------PKLLEDLKNKDDEMSQKKKPLC 440
            .| :|..|.:..|...||   |.| .|.               ||.|:.:...|   :.|...:|
Mouse   301 WI-SLNDISLAGNIWECSRNICSLVNWLRSFKGLRENTIICASPKELQGVNVID---AVKNYSIC 361

  Fly   441 HMSLDNREY-FVQAMP 455
            ..|.....: ..:|:|
Mouse   362 GKSTTTERFDLARALP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	8/19 (42%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		LRR	<131..410	CDD:443914	74/278 (27%)
		leucine-rich repeat	131..154	CDD:275380	2/22 (9%)
		leucine-rich repeat	155..178	CDD:275380	6/22 (27%)
		leucine-rich repeat	179..203	CDD:275380	9/23 (39%)
		leucine-rich repeat	204..227	CDD:275380	6/22 (27%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)
		leucine-rich repeat	276..300	CDD:275380	8/23 (35%)
		leucine-rich repeat	301..324	CDD:275380	3/22 (14%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	3/22 (14%)
Lrrtm3	NP_848793.1	LRRNT	33..61	CDD:214470	10/36 (28%)
		LRR	59..339	CDD:443914	95/363 (26%)
		LRR 1	63..83		9/27 (33%)
		leucine-rich repeat	66..86	CDD:275380	9/19 (47%)
		LRR 2	86..107		5/20 (25%)
		leucine-rich repeat	87..110	CDD:275380	5/41 (12%)
		LRR 3	110..131		8/26 (31%)
		leucine-rich repeat	111..134	CDD:275380	8/28 (29%)
		LRR 4	134..155		6/20 (30%)
		leucine-rich repeat	135..158	CDD:275380	9/23 (39%)
		LRR 5	158..179		6/20 (30%)
		leucine-rich repeat	159..182	CDD:275380	6/22 (27%)
		LRR 6	182..203		6/20 (30%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		LRR 7	206..226		5/19 (26%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		LRR 8	230..251		9/37 (24%)
		leucine-rich repeat	231..254	CDD:275380	10/39 (26%)
		LRR 9	254..275		12/52 (23%)
		leucine-rich repeat	255..279	CDD:275380	12/47 (26%)
		LRR 10	279..300		10/20 (50%)
		leucine-rich repeat	280..300	CDD:275380	10/19 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..410		119/471 (25%)