Protein Alignment CG14762 and Chadl

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_006520805.1
• Gene: Chadl / 214685
• MGIID: 3036284
• Length: 759
• Species: Mus musculus
• Alignment Length: 435
• Identity: 116/435 - (26%)
• Similarity: 174/435 - (40%)
• Gaps: 126/435 - (28%)

  Fly     4 IQLQSG------CTMVVTVVLLLQVLVMD---QVLGQGPPQTQVCPEQSEIAPCICTVKKNGLDI 59
            ::||.|      .::.|.::||..||:..   .|..|..|||           |:|...:.
Mouse     5 LELQGGEMDRPQSSIWVFMLLLFMVLLQSPAWHVAAQRCPQT-----------CVCDNSRR---- 54

  Fly    60 LCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENAL 124
                    |:|                 .||.||.::..                   .|.|
Mouse    55 --------HVT-----------------CRHQNLTEVPN-------------------TIPE--- 72

  Fly   125 SSLGAGLTQ-LDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENK 188
                  ||| ||:..|.:|.:|:.|.|.|.||..|:|.:.::.::...||.||..|.:
Mouse    73 ------LTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLL------- 124

  Fly   189 ITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLD 253
                              |||..|.|:.:||:||..|.:|::||::.|.:..:..|.|..|.||.
Mouse   125 ------------------LNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLT 171

  Fly   254 SLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEA 318
            :|.||||.:..:||..|..|.....|:|..|.:||:..:|..||.. |:.|.|..|::..:|..|
Mouse   172 TLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPA-LRRLSLHHNELQALPGAA 235

  Fly   319 LRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTF-----LNLQKNDIKVLPSLLFENLNSLETLN 378
            |.....|..|:|.:|.:      .:||..|.|..     |.|....::.|....|.:...|.||:
Mouse   236 LSQARSLARLELGHNPL------TYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLD 294

  Fly   379 LQNNKLQRIPQDIMEP--VIDTLRIIDITDNPLNCSCE----LTW 417
            |:.|:|..:|     |  |...||.:.:..|||.|:|.    |.|
Mouse   295 LRGNQLTTLP-----PLQVPGQLRRLRLQGNPLWCACHARPLLEW 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	4/19 (21%)
		leucine-rich repeat	107..129	CDD:275380	2/21 (10%)
		LRR	<131..410	CDD:443914	88/286 (31%)
		leucine-rich repeat	131..154	CDD:275380	11/23 (48%)
		leucine-rich repeat	155..178	CDD:275380	7/22 (32%)
		leucine-rich repeat	179..203	CDD:275380	1/23 (4%)
		leucine-rich repeat	204..227	CDD:275380	10/22 (45%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	10/22 (45%)
		leucine-rich repeat	276..300	CDD:275380	8/23 (35%)
		leucine-rich repeat	301..324	CDD:275380	7/22 (32%)
		leucine-rich repeat	325..349	CDD:275380	6/23 (26%)
		leucine-rich repeat	350..373	CDD:275380	5/27 (19%)
Chadl	XP_006520805.1	LRRNT	43..75	CDD:214470	14/99 (14%)
		leucine-rich repeat	54..72	CDD:275380	7/65 (11%)
		LRR	67..>322	CDD:443914	89/319 (28%)
		leucine-rich repeat	74..97	CDD:275380	10/22 (45%)
		leucine-rich repeat	98..121	CDD:275380	7/22 (32%)
		leucine-rich repeat	122..145	CDD:275380	11/47 (23%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		leucine-rich repeat	170..193	CDD:275380	10/22 (45%)
		leucine-rich repeat	194..217	CDD:275380	8/22 (36%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	8/28 (29%)
		leucine-rich repeat	266..289	CDD:275380	4/22 (18%)
		leucine-rich repeat	312..351	CDD:275380	9/23 (39%)
		LRRNT	405..439	CDD:214470
		leucine-rich repeat	437..460	CDD:275380
		LRR	<455..>687	CDD:443914
		leucine-rich repeat	461..484	CDD:275380
		leucine-rich repeat	485..508	CDD:275380
		leucine-rich repeat	509..532	CDD:275380
		leucine-rich repeat	533..556	CDD:275380
		leucine-rich repeat	557..580	CDD:275380
		leucine-rich repeat	581..604	CDD:275380
		leucine-rich repeat	605..629	CDD:275380
		leucine-rich repeat	630..653	CDD:275380
		leucine-rich repeat	655..677	CDD:275380
		LRRCT	685..733	CDD:214507