Protein Alignment CG14762 and lron-14

DIOPT Version :9

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001255400.1
• Gene: lron-14 / 188075
• WormBaseID: WBGene00011454
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 96/419 - (22%)
• Similarity: 170/419 - (40%)
• Gaps: 105/419 - (25%)

  Fly    14 VTVVLLLQVLVMDQV----LGQGPPQTQVCPEQSEIAPCICTVKKN-GLDILCETTDLAHITKSM 73
            ::|:.||.:.::..:    .....|....||.:.:   |....::| .:.::|:...|...|
 Worm     1 MSVLPLLHLFLISSLQIAPTATSSPSQFPCPTRCQ---CYADNEQNQQVHLICKWEQLNVTT--- 59

  Fly    74 GTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTI---HNSSLAAIEENALSSLGAGLTQLD 135
                        |:|...:|            :|.|||   ::|...:...::|......|.:|:
 Worm    60 ------------LQLARPDL------------VRTLTIKCPYHSPKVSTPPHSLFQGFRNLDRLE 100

  Fly   136 VSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGL 200
            :....:.|||......|..|..|.:.:.|||......|..:..|..|.|..|:: :|:|.:.|.|
 Worm   101 LDRCLIDTVPEGLFAGLGQLYSLIVKNAKITDFPREIFAHVPNLMTLDLSGNRL-RIEPYSLRSL 164

  Fly   201 EDHIKRLNLGGND---LTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGL-QSLDSLILAHNM 261
            ::.| .|::..||   |||    .|..|:.||.:.:..|||..|   ||... ::|..|.:.||:
 Worm   165 QNLI-HLDVSDNDIGFLTN----TLISLTKLKVITMNNNKITNI---DFRRFPENLTDLSIRHNL 221

  Fly   262 ITT---VPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLH 323
            ::|   |||:..:    |..|:|.||::..:.              .|....::.:|:|
 Worm   222 VSTIHYVPASARN----LKRLDLAGNRMEFVG--------------GLTTGAVNVLPAE------ 262

  Fly   324 RLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIP 388
             |:|:||.||.:..|.:.|                         ||:|.:|..|:|:||.|:.:.
 Worm   263 -LKHVDLSNNKLTYLHDHA-------------------------FEHLTNLILLDLKNNSLKEVK 301

  Fly   389 QDIMEPVIDTLRIIDITDNPLNCSCELTW 417
            ..........:::. :::|||.|.|...|
 Worm   302 SSSFAGSKFQVKLF-LSENPLLCHCNHKW 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	3/19 (16%)
		LRR_RI	93..384	CDD:238064	76/300 (25%)
		leucine-rich repeat	107..129	CDD:275380	6/24 (25%)
		leucine-rich repeat	131..154	CDD:275380	6/22 (27%)
		LRR_8	154..214	CDD:290566	18/62 (29%)
		leucine-rich repeat	155..178	CDD:275380	6/22 (27%)
		leucine-rich repeat	179..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	9/25 (36%)
		LRR_8	226..286	CDD:290566	21/63 (33%)
		leucine-rich repeat	228..251	CDD:275380	8/23 (35%)
		leucine-rich repeat	252..275	CDD:275380	8/25 (32%)
		LRR_8	276..335	CDD:290566	14/58 (24%)
		leucine-rich repeat	276..300	CDD:275380	5/23 (22%)
		leucine-rich repeat	301..324	CDD:275380	3/22 (14%)
		leucine-rich repeat	325..349	CDD:275380	8/23 (35%)
		LRR_8	349..409	CDD:290566	10/59 (17%)
		leucine-rich repeat	350..373	CDD:275380	3/22 (14%)
lron-14	NP_001255400.1	leucine-rich repeat	98..119	CDD:275380	5/20 (25%)
		LRR_8	119..177	CDD:290566	17/59 (29%)
		leucine-rich repeat	120..143	CDD:275380	6/22 (27%)
		LRR_RI	142..389	CDD:238064	64/248 (26%)
		leucine-rich repeat	144..166	CDD:275380	8/22 (36%)
		leucine-rich repeat	167..189	CDD:275380	9/26 (35%)
		leucine-rich repeat	190..211	CDD:275380	8/23 (35%)
		leucine-rich repeat	212..234	CDD:275380	8/21 (38%)
		leucine-rich repeat	235..261	CDD:275380	6/39 (15%)
		LRR_8	262..321	CDD:290566	19/91 (21%)
		leucine-rich repeat	263..286	CDD:275380	11/47 (23%)
		leucine-rich repeat	287..310	CDD:275380	6/22 (27%)
		leucine-rich repeat	349..404	CDD:275380
		LRR_8	456..515	CDD:290566
		leucine-rich repeat	458..481	CDD:275380
		LRR_4	481..520	CDD:289563
		leucine-rich repeat	482..504	CDD:275380
		leucine-rich repeat	505..526	CDD:275380

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X351
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000