Protein Alignment CG14762 and sym-1

DIOPT Version :9

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_510426.1
• Gene: sym-1 / 181555
• WormBaseID: WBGene00006366
• Length: 680
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 117/440 - (26%)
• Similarity: 194/440 - (44%)
• Gaps: 56/440 - (12%)

  Fly    18 LLLQVLVMDQVLGQGPPQTQVCPE--QSEIAPCICTVKKNGLDILCETTDLAHITKSMGTLKGKS 80
            :||::.|...||   |.....||:  |::.| |.|.....|..|.|...|...:.:.:.|.....
 Worm     1 MLLRLCVALLVL---PACLAFCPKLFQNQTA-CSCDSTVEGPVIKCSGHDGLRMVEKLSTTTTME 61

  Fly    81 PIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVP 145
              :..|.|.:.::.::....|..|.|:.|.:.|:.:..|.::|.:.|...:.:|.:|.|.:|.||
 Worm    62 --VRELALENADIIEVGPKAFKTLRIKKLILSNNRIEKIHDHAFTGLENVMQELSLSENNLKEVP 124

  Fly   146 SQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGLEDHIKRLNLG 210
            :.||..|..|.||:|..|||..|...||..:.:|..:.|..|:|..:..:.|..::..::.|.|.
 Worm   125 TSALAGLRVLNILSLKCNKIENITTKAFVNMTSLIDVNLGCNQICSMAADTFANVKMSLQNLILD 189

  Fly   211 GNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTL 275
            .|.:|..|.||:..::.|..|.|:.|||..|.:.||..|.||..|.|..|.|:.:......:...
 Worm   190 NNCMTEFPSKAVRNMNNLIALHIKYNKINAIRQNDFVNLTSLSMLSLNGNNISEIKGGALQNTPN 254

  Fly   276 LNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAE 340
            |:.|.|..|.:..:|....:..:: ||.|.|..|....|..|....|..::||:|.:|.|:.:|.
 Worm   255 LHYLYLNENNLQTLDNGVLEQFKQ-LQVLDLSFNNFTDITKEMFEGLESIQHLNLDSNRISAVAP 318

  Fly   341 DAFTGF----------------------GDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNK 383
            .||.|.                      ...|..::|..|:|:.:..|.|::|.:|.||:|.|||
 Worm   319 GAFAGTPLLLLWLPNNCLTEVSQQTLKGAPFLRMVSLSNNNIREVHELSFDHLPNLHTLDLANNK 383

  Fly   384 LQRI-------PQDIMEPVIDTLRIIDITDNPLNC---------SCELTW 417
            :..:       |:::         .:.:.:||:.|         |.|..|
 Worm   384 IMSLQNKSLSGPENL---------AVRLQENPVVCVKNGFHVLNSGEAIW 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	3/19 (16%)
		LRR_RI	93..384	CDD:238064	90/312 (29%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		leucine-rich repeat	131..154	CDD:275380	9/22 (41%)
		LRR_8	154..214	CDD:290566	18/59 (31%)
		leucine-rich repeat	155..178	CDD:275380	10/22 (45%)
		leucine-rich repeat	179..203	CDD:275380	5/23 (22%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		LRR_8	226..286	CDD:290566	20/59 (34%)
		leucine-rich repeat	228..251	CDD:275380	10/22 (45%)
		leucine-rich repeat	252..275	CDD:275380	5/22 (23%)
		LRR_8	276..335	CDD:290566	17/58 (29%)
		leucine-rich repeat	276..300	CDD:275380	5/23 (22%)
		leucine-rich repeat	301..324	CDD:275380	8/22 (36%)
		leucine-rich repeat	325..349	CDD:275380	9/45 (20%)
		LRR_8	349..409	CDD:290566	16/66 (24%)
		leucine-rich repeat	350..373	CDD:275380	7/22 (32%)
sym-1	NP_510426.1	leucine-rich repeat	62..81	CDD:275380	2/18 (11%)
		LRR_5	74..208	CDD:290045	39/133 (29%)
		LRR_RI	81..384	CDD:238064	89/303 (29%)
		leucine-rich repeat	86..108	CDD:275380	5/21 (24%)
		leucine-rich repeat	110..133	CDD:275380	9/22 (41%)
		leucine-rich repeat	134..157	CDD:275380	10/22 (45%)
		leucine-rich repeat	158..182	CDD:275380	5/23 (22%)
		LRR_8	182..241	CDD:290566	22/58 (38%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		leucine-rich repeat	207..230	CDD:275380	10/22 (45%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		LRR_8	253..313	CDD:290566	17/60 (28%)
		leucine-rich repeat	255..278	CDD:275380	5/22 (23%)
		leucine-rich repeat	279..302	CDD:275380	8/22 (36%)
		LRR_8	302..384	CDD:290566	22/81 (27%)
		leucine-rich repeat	303..323	CDD:275380	8/19 (42%)
		leucine-rich repeat	350..373	CDD:275380	7/22 (32%)
		leucine-rich repeat	374..394	CDD:275380	7/19 (37%)
		leucine-rich repeat	399..410	CDD:275378	2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I2985
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960