Protein Alignment CG14762 and lron-15

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_495322.3
• Gene: lron-15 / 174079
• WormBaseID: WBGene00016974
• Length: 1275
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 129/495 - (26%)
• Similarity: 216/495 - (43%)
• Gaps: 96/495 - (19%)

  Fly    43 SEIAPCICTVKKNGLDILCETTDLAHITK--SMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLALD 105
            |..||.|.: :::.:.|:|..|..|.:.:  :..|:||..|.|..|.:...::..:|...|...|
 Worm    56 SVTAPGIFS-QESPIHIMCHHTSSATVLQLPNSETMKGPPPHIVALSMTDGSMAFVQQDAFKHHD 119

  Fly   106 IRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHN 170
            |:.|...|:.:..:..||...|...|||||:|.|.:..:|:.||.:|..|.||:|.:|:|.|:.:
 Worm   120 IQTLDFSNNQIQTVNVNAFRGLEMKLTQLDLSHNNLSVIPTWALTYLHSLQILHLENNRIDVLRS 184

  Fly   171 NAFEGLET---------------------------LEILTLYENKITQIDPEAFRGLEDHIKRLN 208
            |.|:  ||                           |.:|.|..|:||:|..   ..|...:|.|.
 Worm   185 NTFD--ETQLNNLQFLYLDNNQLRIIPNLAFNHLRLVVLMLANNRITEIQK---MSLPQTLKFLV 244

  Fly   209 LGGNDLTNIPQKALSILSTLKKLEIQ------------------------ENKIRTISEGDFEGL 249
            |..|.||.||..||:.|.||:.::::                        .||:|.:.:..|...
 Worm   245 LRNNLLTQIPYVALNDLKTLQSIDLEGNNITHLMDTNEVTFESEMKVILRNNKVRRLDKHSFRSF 309

  Fly   250 QSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTI 314
            :.:..|.:::|.|.||..:.|..:..:.||:|..|:|:.:.:...|...:.|:.|:|.:|.||..
 Worm   310 RKIRELDISYNQIQTVEDSSFETVGHMQSLDLSYNRIAYLPRGMLKNFAKTLKTLKLAENMIHAT 374

  Fly   315 PSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNL 379
            | ||||.|..|.||:|..|.:|.:..|...|..|:|..|.:..|.::.:|..:...:..||.|::
 Worm   375 P-EALRDLRNLTHLNLNGNKLNRIDGDVLKGCTDTLVELFIANNYLEHIPHGVLSGMKQLEHLDI 438

  Fly   380 QNNKLQRIPQ-----DIMEPVIDTLRIIDITDNPLNCSCELTWF--------------------P 419
            ..||:..:.:     .|.:....|:|.:::..|.:|...:...|                    |
 Worm   439 SKNKIMSLKKPTSLLSITKEETSTVRRLNLAGNRINNMSDYLIFEHMPLLTYVDVSFNRIRFISP 503

  Fly   420 KLLEDLKNKDDEMSQKKK-----------PLCHMSLDNRE 448
            ::.|.|||.:....|..:           .|.|:.|||.:
 Worm   504 RVFEKLKNLESLFLQNNQLAHFPSLFRLDKLRHLMLDNNQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	3/19 (16%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		LRR	<131..410	CDD:443914	93/334 (28%)
		leucine-rich repeat	131..154	CDD:275380	11/22 (50%)
		leucine-rich repeat	155..178	CDD:275380	9/22 (41%)
		leucine-rich repeat	179..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	11/22 (50%)
		leucine-rich repeat	228..251	CDD:275380	5/46 (11%)
		leucine-rich repeat	252..275	CDD:275380	6/22 (27%)
		leucine-rich repeat	276..300	CDD:275380	6/23 (26%)
		leucine-rich repeat	301..324	CDD:275380	12/22 (55%)
		leucine-rich repeat	325..349	CDD:275380	8/23 (35%)
		leucine-rich repeat	350..373	CDD:275380	4/22 (18%)
lron-15	NP_495322.3	PLN00113	120..>648	CDD:215061	112/430 (26%)
		leucine-rich repeat	120..144	CDD:275380	6/23 (26%)
		leucine-rich repeat	145..168	CDD:275380	11/22 (50%)
		leucine-rich repeat	169..194	CDD:275380	11/26 (42%)
		leucine-rich repeat	195..217	CDD:275380	0/21 (0%)
		leucine-rich repeat	218..239	CDD:275380	8/23 (35%)
		leucine-rich repeat	240..263	CDD:275380	11/22 (50%)
		leucine-rich repeat	264..311	CDD:275380	5/46 (11%)
		leucine-rich repeat	312..335	CDD:275380	6/22 (27%)
		leucine-rich repeat	336..356	CDD:275380	5/19 (26%)
		leucine-rich repeat	361..383	CDD:275380	12/22 (55%)
		leucine-rich repeat	384..405	CDD:275380	7/20 (35%)
		leucine-rich repeat	409..432	CDD:275380	4/22 (18%)
		LRR	415..840	CDD:443914	24/129 (19%)
		leucine-rich repeat	433..462	CDD:275380	6/28 (21%)
		leucine-rich repeat	463..487	CDD:275380	4/23 (17%)
		leucine-rich repeat	488..511	CDD:275380	3/22 (14%)
		leucine-rich repeat	512..533	CDD:275380	1/20 (5%)
		leucine-rich repeat	534..557	CDD:275380	5/10 (50%)
		leucine-rich repeat	558..581	CDD:275380
		leucine-rich repeat	584..607	CDD:275380
		leucine-rich repeat	608..631	CDD:275380
		leucine-rich repeat	632..655	CDD:275380
		leucine-rich repeat	656..676	CDD:275380
		leucine-rich repeat	680..703	CDD:275380
		leucine-rich repeat	704..749	CDD:275380
		leucine-rich repeat	726..739	CDD:275378
		leucine-rich repeat	750..771	CDD:275380
		leucine-rich repeat	774..797	CDD:275380
		LRR	<791..1089	CDD:443914
		leucine-rich repeat	798..845	CDD:275380
		leucine-rich repeat	846..869	CDD:275380
		leucine-rich repeat	870..893	CDD:275380
		leucine-rich repeat	894..915	CDD:275380
		leucine-rich repeat	940..963	CDD:275380
		leucine-rich repeat	964..987	CDD:275380
		leucine-rich repeat	988..1009	CDD:275380
		leucine-rich repeat	1038..1064	CDD:275380
		leucine-rich repeat	1113..1139	CDD:275380