DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14762 and Lrrn1

DIOPT Version :9

Sequence 1:NP_001246198.1 Gene:CG14762 / 35768 FlyBaseID:FBgn0033250 Length:498 Species:Drosophila melanogaster
Sequence 2:NP_032542.1 Gene:Lrrn1 / 16979 MGIID:106038 Length:716 Species:Mus musculus


Alignment Length:422 Identity:120/422 - (28%)
Similarity:187/422 - (44%) Gaps:59/422 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 QSGCTMVVTVVLLLQVLVMDQVLGQGPPQTQVCPEQSEIAPCICTVK---------KNGLDILCE 62
            ::.|.:|:.  ||:..|....:|      |..||:.     |:|.::         :....:.| 
Mouse     8 KAACQVVLG--LLITSLTESSIL------TSECPQL-----CVCEIRPWFTPQSTYREATTVDC- 58

  Fly    63 TTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIEENALSSL 127
             .|| .:|:..|.|...:.:   |.|:.||:.|....:....::..|....::...|:|..|::|
Mouse    59 -NDL-RLTRIPGNLSSDTQV---LLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANL 118

  Fly   128 GAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTLYENKITQI 192
             ..||.|.:..||:..:....||.|.:|..|.:|||:|:.|..|||.||:.|..|.|..||:..|
Mouse   119 -TQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISTISANAFSGLKNLLRLHLNSNKLKVI 182

  Fly   193 DPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGLQSLDSLIL 257
            |...|               |.|          ..|:.|.|.||.:..|.:.:|..|.:|.||:|
Mouse   183 DSRWF---------------DST----------PNLEILMIGENPVIGILDMNFRPLSNLRSLVL 222

  Fly   258 AHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPL 322
            |...:|.||.|....|..|.||....||:..:.:.|.:.: .||::|.|..|.||.|.....:.:
Mouse   223 AGMYLTDVPGNALVGLDSLESLSFYDNKLIKVPQLALQKV-PNLKFLDLNKNPIHKIQEGDFKNM 286

  Fly   323 HRLRHLDLRNNNINVLAEDAFTGFG-DSLTFLNLQKN-DIKVLPSLLFENLNSLETLNLQNNKLQ 385
            .||:.|.: ||...:::.|.:.... ..||.|....| .:..:..|.|.::.:||:|.|.||.|.
Mouse   287 LRLKELGI-NNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALN 350

  Fly   386 RIPQDIMEPVIDTLRIIDITDNPLNCSCELTW 417
            .:.|..:|. :..||.|.|..|||.|.|.:.|
Mouse   351 AVYQKTVES-LPNLREISIHSNPLRCDCVIHW 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14762NP_001246198.1 leucine-rich repeat 85..105 CDD:275380 5/19 (26%)
LRR_RI 93..384 CDD:238064 86/292 (29%)
leucine-rich repeat 107..129 CDD:275380 5/21 (24%)
leucine-rich repeat 131..154 CDD:275380 8/22 (36%)
LRR_8 154..214 CDD:290566 20/59 (34%)
leucine-rich repeat 155..178 CDD:275380 12/22 (55%)
leucine-rich repeat 179..203 CDD:275380 8/23 (35%)
leucine-rich repeat 204..227 CDD:275380 2/22 (9%)
LRR_8 226..286 CDD:290566 22/59 (37%)
leucine-rich repeat 228..251 CDD:275380 8/22 (36%)
leucine-rich repeat 252..275 CDD:275380 10/22 (45%)
LRR_8 276..335 CDD:290566 19/58 (33%)
leucine-rich repeat 276..300 CDD:275380 6/23 (26%)
leucine-rich repeat 301..324 CDD:275380 7/22 (32%)
leucine-rich repeat 325..349 CDD:275380 5/24 (21%)
LRR_8 349..409 CDD:290566 20/60 (33%)
leucine-rich repeat 350..373 CDD:275380 6/23 (26%)
Lrrn1NP_032542.1 LRR_RI 11..273 CDD:238064 85/307 (28%)
leucine-rich repeat 54..73 CDD:275380 6/21 (29%)
LRR 1 73..95 5/24 (21%)
leucine-rich repeat 74..96 CDD:275380 5/24 (21%)
LRR 2 96..117 4/20 (20%)
leucine-rich repeat 97..120 CDD:275380 5/23 (22%)
LRR_8 119..179 CDD:290566 24/59 (41%)
LRR 3 120..141 6/20 (30%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR 4 144..165 10/20 (50%)
leucine-rich repeat 145..168 CDD:275380 12/22 (55%)
LRR 5 168..189 8/35 (23%)
leucine-rich repeat 169..192 CDD:275380 10/47 (21%)
LRR 6 192..213 7/20 (35%)
leucine-rich repeat 193..216 CDD:275380 8/22 (36%)
LRR_RI 211..>376 CDD:238064 54/167 (32%)
LRR_8 215..275 CDD:290566 21/60 (35%)
LRR 7 216..237 9/20 (45%)
leucine-rich repeat 217..240 CDD:275380 10/22 (45%)
LRR 8 240..261 6/20 (30%)
leucine-rich repeat 241..264 CDD:275380 6/23 (26%)
LRR_8 263..323 CDD:290566 17/60 (28%)
LRR 9 264..285 8/20 (40%)
leucine-rich repeat 265..288 CDD:275380 7/22 (32%)
leucine-rich repeat 289..313 CDD:275380 5/24 (21%)
LRR_8 312..373 CDD:290566 20/61 (33%)
leucine-rich repeat 314..335 CDD:275380 6/20 (30%)
leucine-rich repeat 339..362 CDD:275378 9/23 (39%)
leucine-rich repeat 363..375 CDD:275378 7/11 (64%)
LRRCT 371..419 CDD:214507 6/11 (55%)
I-set 429..516 CDD:254352
Ig 431..516 CDD:299845
fn3 531..600 CDD:278470
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 692..716
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X351
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.910

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