Protein Alignment CG14762 and conv

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_061510197.1
• Gene: conv / 1277810
• VectorBaseID: AGAMI1_013247
• Length: 1120
• Species: Anopheles gambiae
• Alignment Length: 568
• Identity: 135/568 - (23%)
• Similarity: 244/568 - (42%)
• Gaps: 130/568 - (22%)

  Fly     3 GIQLQSGCTMVVTVVLLLQVLVMDQVLGQGPPQTQV----------CPEQSE-IAPCICTV-KKN 55
            |.:|.:|...||       :|.:..|....||....          |||::: |.|||||. ..:
Mosquito    12 GARLVNGLVFVV-------LLTIGWVSVCPPPSAHAEYIPPGPKYKCPEKTKLIYPCICTQGTDD 69

  Fly    56 GLDILCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGFVFLALDIRHLTIHNSSLAAIE 120
            |:.|.||.::||.::.:...|...:..|..|:|:...:..|.|.:...|.::||.:.::.||:|.
Mosquito    70 GIFIQCENSNLASLSVAFINLASMNVPIVQLRLQRCKIKNLFGTLLHRLQVKHLHLTDTPLASIA 134

  Fly   121 ENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLE---TLEIL 182
            ::|...:...|.:|.:...:|...|::||:.|..|.:||::.:||.::...:|.|.:   :||.|
Mosquito   135 DHAFYGINDTLQELHLVHTEMTQFPTEALKILGLLKVLNIDGHKIDLLAKGSFAGAQFEGSLEKL 199

  Fly   183 TLYENKITQIDPEAFRGLEDHIKRLNLGGN----------------------------------- 212
            .|....:|::..:.|..|: .:|.|:|.||
Mosquito   200 HLVNGPLTELAADIFGSLK-KVKTLDLHGNQLGTLKKGQFKGMREVEILDLSFNNLTKLDATHVS 263

  Fly   213 DLT-----NIPQKALSIL--------STLKKLEIQENKIRTISEGDFEGLQSLDSLILAHNMITT 264
            |||     |:...||:.:        :.|:.:.:..|.||.|....|.|::.|..|.|:.|||:.
Mosquito   264 DLTKMTWCNVSNNALTEITRGTFARNTVLRVVNMAANAIRKIDANTFRGMRFLRRLYLSDNMISD 328

  Fly   265 VPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLD 329
            |....|..:|.:.:::|..|:|..:|...|..| ..::.:.|.:|:|..|..:|.:.|: |.|::
Mosquito   329 VGRGTFGSVTRIGTIDLARNRIKKVDFQMFFQL-NYVELIDLAENEITEIQKDAFKDLY-LTHIN 391

  Fly   330 LRNNNINVLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFE------------------------N 370
            :.:|.:..:...:|.... ::|.|:|..|.|:.:|...|:                        |
Mosquito   392 ISHNRLETIEPKSFINCA-NMTVLDLSHNLIRAIPRTAFDETTYATEWIVTHNLLTNMTQLPLSN 455

  Fly   371 LNSLETLNLQNNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTWFPKLLEDLKNKDDEMSQK 435
            :..|:.||:..|.|..||::.. |.:..|..||::.|.::...... |..|| .|:|.:
Mosquito   456 MTGLKILNVSYNNLVEIPKNTF-PKLYELHTIDVSHNNISHIYNAV-FQNLL-SLRNLN------ 511

  Fly   436 KKPLCHMSLDNREYFVQAMPTEKMHCAGLNVSPSPTSGGLMRILQVNI 483
               |.|.:|:                   .:.|| |.|.|..:|::::
Mosquito   512 ---LSHNALE-------------------KIGPS-TFGTLPTLLELDL 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	4/19 (21%)
		leucine-rich repeat	107..129	CDD:275380	6/21 (29%)
		LRR	<131..410	CDD:443914	84/353 (24%)
		leucine-rich repeat	131..154	CDD:275380	7/22 (32%)
		leucine-rich repeat	155..178	CDD:275380	7/25 (28%)
		leucine-rich repeat	179..203	CDD:275380	7/23 (30%)
		leucine-rich repeat	204..227	CDD:275380	11/70 (16%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	8/22 (36%)
		leucine-rich repeat	276..300	CDD:275380	6/23 (26%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..349	CDD:275380	4/23 (17%)
		leucine-rich repeat	350..373	CDD:275380	8/46 (17%)
conv	XP_061510197.1	None