Protein Alignment CG14762 and LOC101730428

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_004919457.2
• Gene: LOC101730428 / 101730428
• XenbaseID: XB-GENE-29084559
• Length: 970
• Species: Xenopus tropicalis
• Alignment Length: 739
• Identity: 145/739 - (19%)
• Similarity: 215/739 - (29%)
• Gaps: 331/739 - (44%)

  Fly    35 QTQVCPEQSEIAPCICTVKKNGLDILCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGF 99
            :|| |...:..:..|..:.|:...::.:..||..:|.|  |.||.| ::..|.|.:|.:...:
 Frog    34 ETQ-CTHMALTSVPIADIHKDTAILILKYNDLKSVTAS--TFKGLS-LLLELDLSNNAMTNFK-- 92

  Fly   100 VFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNK 164
            |..||.:..|.:.|:||..|..   .||...|.:|.:|.|::.:||..|..||.:|..|.|.||.
 Frog    93 VEFALGLEELNLANNSLDHIPN---LSLLTNLNKLILSHNRITSVPDAAFHHLKNLQQLYLQHNG 154

  Fly   165 ITVIHNNAFEGLETLEILTLYENK------------------------ITQIDPEAFRGLE---- 201
            |..:....||..:.|..|.|..||                        :|:|..:.|.||.
 Frog   155 IHYLSEQVFEHSQQLHTLDLSYNKLVSVPRHLISHAEKLDKFYLTGNRLTEIPDDFFEGLANLAY 219

  Fly   202 ----------------------------------------------------------DHIKRLN 208
                                                                      ||..  |
 Frog   220 VYLDDNPFQCNCALENFKAWVEDNSFNIYTMKDGDTTQDEYSVVCTSPNKVPLLNFPMDHCS--N 282

  Fly   209 LGGND---------------------------------------LTNIP-------------QKA 221
            .|.||                                       ||:.|             .:.
 Frog   283 TGDNDYVTNTVGTDYVKYSVTSIHSILTTQKARLVSPTMLQTSTLTDAPTTIKSETTEFEISSET 347

  Fly   222 LSILSTL--------KKLEIQENKI----RTISEGDFEG---------LQSLDS----------- 254
            .:|||||        ...|.|.:|:    ::|:.|..|.         |.:||:
 Frog   348 PTILSTLDAAEAATTTTAEFQTSKLTDAPKSITPGSTEFEISSETPMILSTLDAAEATTTAEFQT 412

  Fly   255 ----------------------------------------------------------------- 254
                                                                             
 Frog   413 STQTDAPTTIKAGSPEFEVSSETPMILSTMDAAEATTTAEFQTSTQTSKTSASRSACSHLCTTEK 477

  Fly   255 ------------------------------LILAHNMITTVPANVFSHLTLLNSLELEGNKISVI 289
                                          |||.:|.:|::..:....|.|| .|:|..|.::..
 Frog   478 NVVKDKQETQCTHMGLTYIPLTCIPSNTSILILKYNDLTSITTSTLKDLPLL-ELDLSNNAVTSF 541

  Fly   290 DKDAFKGLEE------------------NLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNIN 336
            ..|...||||                  ||:.|.|..|.|..:|..|...|..|.||.|::|.|:
 Frog   542 TADFPLGLEELNLANNSINHIPDLSPLTNLKTLILSHNYISCVPDTAFHDLKNLHHLYLQHNGIH 606

  Fly   337 VLAEDAFTGFGDSLTFLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLRI 401
            .|:|..|.. ...|..|:|..|.:..:|..|..:...|:...|..|:|..||.|..|. :..|..
 Frog   607 YLSEQVFER-SQQLQTLDLSNNKLIGVPWHLISHAKKLDKFYLTGNRLMEIPDDFFEG-LKNLAY 669

  Fly   402 IDITDNPLNCSCE----LTWFP------KLLEDLKNKDDE-----MSQKKKPLCHMSLDNREYFV 451
            :.:.|||..|:|.    .||..      ..::|.....||     .|..|.||.:.|:|
 Frog   670 VYLDDNPFRCNCASENFKTWVEVNAFNIYTIKDGATTQDEYSVVCASPYKVPLLNFSMD------ 728

  Fly   452 QAMPTEKMHCA-----GLNVSPSP 470
                    ||:     .:..:|:|
 Frog   729 --------HCSTEPSKPITTTPTP 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	5/19 (26%)
		leucine-rich repeat	107..129	CDD:275380	7/21 (33%)
		LRR	<131..410	CDD:443914	102/561 (18%)
		leucine-rich repeat	131..154	CDD:275380	9/22 (41%)
		leucine-rich repeat	155..178	CDD:275380	8/22 (36%)
		leucine-rich repeat	179..203	CDD:275380	10/109 (9%)
		leucine-rich repeat	204..227	CDD:275380	9/74 (12%)
		leucine-rich repeat	228..251	CDD:275380	8/43 (19%)
		leucine-rich repeat	252..275	CDD:275380	8/128 (6%)
		leucine-rich repeat	276..300	CDD:275380	9/41 (22%)
		leucine-rich repeat	301..324	CDD:275380	8/22 (36%)
		leucine-rich repeat	325..349	CDD:275380	9/23 (39%)
		leucine-rich repeat	350..373	CDD:275380	6/22 (27%)
LOC101730428	XP_004919457.2	leucine-rich repeat	56..77	CDD:275380	8/23 (35%)
		LRR	57..>227	CDD:443914	48/177 (27%)
		leucine-rich repeat	78..93	CDD:275380	3/16 (19%)
		leucine-rich repeat	99..120	CDD:275380	7/23 (30%)
		leucine-rich repeat	121..144	CDD:275380	9/22 (41%)
		leucine-rich repeat	145..168	CDD:275380	8/22 (36%)
		leucine-rich repeat	169..192	CDD:275380	5/22 (23%)
		leucine-rich repeat	193..216	CDD:275380	5/22 (23%)
		LRRCT	225..278	CDD:214507	0/52 (0%)
		LRR	496..>675	CDD:443914	49/181 (27%)
		leucine-rich repeat	507..526	CDD:275380	5/18 (28%)
		leucine-rich repeat	528..543	CDD:275380	5/15 (33%)
		leucine-rich repeat	549..570	CDD:275380	3/20 (15%)
		leucine-rich repeat	571..594	CDD:275380	8/22 (36%)
		leucine-rich repeat	595..618	CDD:275380	9/23 (39%)
		leucine-rich repeat	619..642	CDD:275380	6/22 (27%)
		leucine-rich repeat	643..666	CDD:275380	8/23 (35%)
		LRRCT	675..728	CDD:214507	14/52 (27%)