Protein Alignment CG14762 and lrrn3b

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_009298331.1
• Gene: lrrn3b / 100535105
• ZFINID: ZDB-GENE-170217-3
• Length: 706
• Species: Danio rerio
• Alignment Length: 487
• Identity: 119/487 - (24%)
• Similarity: 195/487 - (40%)
• Gaps: 131/487 - (26%)

  Fly    39 CPEQSEIAPCICTVK----KNGLDILCETTDLAHITKSMGTLKGKSPIIFYLKLRHNNLPKLQGF 99
            ||:.     |:|.::    .:.:.:...|.|    ...:|        :|.|..|
Zfish    29 CPKL-----CVCEIRPWFSPSSVYMEAPTID----CNDLG--------LFKLPTR---------- 66

  Fly   100 VFLALDIRHLTIHNSSLAAIEENALSSLGAGLTQLDVSLNQMKTVPSQALQHLFHLLILNLNHNK 164
              |.||.:.|.:..:::|. .|:.|..| ..:|::|:|.|.:.::....:..|..||.|::..|.
Zfish    67 --LPLDTQVLLLQTNNIAK-NEHPLDYL-TNITEIDLSQNNLSSINDINIGSLPQLLSLHMEENW 127

  Fly   165 ITVIHNNAFEGLETLEILTLYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLK 229
            |..:.:|:...|..|:.|.|..|.|:.|.|||||||:. :.||:|..|.|..|..:....|..|:
Zfish   128 ICSLPDNSLSQLTNLQELYLNHNLISLISPEAFRGLQS-LLRLHLNSNRLQIIKSEWFEPLPNLE 191

  Fly   230 KLEIQENKIRTISEGDFEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAF 294
            .|.|.||.:.:|.:.:|:.|::|.||:                ||.:|        :|.|..|:|
Zfish   192 ILMIGENPVLSIQDMNFKPLRNLRSLV----------------LTRMN--------LSQIPDDSF 232

  Fly   295 KGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTFLNLQKND 359
            .|| :||:.:...||....:|..|||.|..|:.|||..|.|..:..      ||.:..|:|::..
Zfish   233 LGL-DNLESISFYDNTFPKVPHGALRHLKSLKFLDLNKNPIGRIQR------GDFVDMLHLKELG 290

  Fly   360 IKVLPSLL-------------------------------FENLNSLETLNLQNNKLQRIPQDIME 393
            |..:|.|:                               |..|..||||.|..|.|..:.:..:|
Zfish   291 INSMPELVSIDSFALNNLPELTKIEATNNPKLSYIHPNAFYRLPRLETLMLNGNALSALHRITVE 355

  Fly   394 PVIDTLRIIDITDNPLNCSCELTWFPKLLEDLKNKDDEMSQKKKPLCHMSLDNREYFVQAMPTEK 458
            . :..||.:.:..||:.|.|.:.|.                      :|:..|    ::.|..:.
Zfish   356 S-LPNLREVSMHSNPIRCDCVVRWM----------------------NMNKTN----IRFMEPDS 393

  Fly   459 MHCAGLNVSPSPTSGGLMRILQVNILAQIAVC 490
            :.|    |.|....|  ..:.||:....:.:|
Zfish   394 LFC----VEPPEYEG--QHVRQVHFREMMEIC 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380	3/19 (16%)
		leucine-rich repeat	107..129	CDD:275380	5/21 (24%)
		LRR	<131..410	CDD:443914	88/309 (28%)
		leucine-rich repeat	131..154	CDD:275380	5/22 (23%)
		leucine-rich repeat	155..178	CDD:275380	7/22 (32%)
		leucine-rich repeat	179..203	CDD:275380	13/23 (57%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	4/22 (18%)
		leucine-rich repeat	276..300	CDD:275380	7/23 (30%)
		leucine-rich repeat	301..324	CDD:275380	8/22 (36%)
		leucine-rich repeat	325..349	CDD:275380	7/23 (30%)
		leucine-rich repeat	350..373	CDD:275380	7/53 (13%)
lrrn3b	XP_009298331.1	leucine-rich repeat	52..70	CDD:275380	7/41 (17%)
		leucine-rich repeat	71..93	CDD:275380	5/23 (22%)
		LRR	<72..325	CDD:443914	79/286 (28%)
		leucine-rich repeat	95..117	CDD:275380	5/21 (24%)
		leucine-rich repeat	118..141	CDD:275380	7/22 (32%)
		leucine-rich repeat	142..165	CDD:275380	13/22 (59%)
		leucine-rich repeat	166..189	CDD:275380	7/22 (32%)
		leucine-rich repeat	190..213	CDD:275380	8/22 (36%)
		leucine-rich repeat	214..237	CDD:275380	12/47 (26%)
		leucine-rich repeat	238..261	CDD:275380	8/22 (36%)
		leucine-rich repeat	262..285	CDD:275380	8/28 (29%)
		leucine-rich repeat	286..310	CDD:275380	4/23 (17%)
		LRR_8	309..370	CDD:404697	13/61 (21%)
		leucine-rich repeat	311..333	CDD:275380	1/21 (5%)
		leucine-rich repeat	336..357	CDD:275380	8/21 (38%)
		leucine-rich repeat	360..372	CDD:275378	4/11 (36%)
		LRRCT	368..411	CDD:214507	13/74 (18%)
		Ig	421..513	CDD:472250
		Ig strand B	440..444	CDD:409353
		Ig strand C	453..457	CDD:409353
		Ig strand E	479..483	CDD:409353
		Ig strand F	493..498	CDD:409353
		Ig strand G	506..509	CDD:409353
		fn3	518..593	CDD:394996