DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14762 and lrfn4b

DIOPT Version :9

Sequence 1:NP_001246198.1 Gene:CG14762 / 35768 FlyBaseID:FBgn0033250 Length:498 Species:Drosophila melanogaster
Sequence 2:XP_021333806.1 Gene:lrfn4b / 100149980 ZFINID:ZDB-GENE-070705-473 Length:1131 Species:Danio rerio


Alignment Length:629 Identity:120/629 - (19%)
Similarity:198/629 - (31%) Gaps:259/629 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 MDQVLGQGPPQTQVC----PEQSEIAPCICTVKKNGLDILCETTDLAHITKSMGTLKGKSPIIFY 85
            :|.:.|..||:.:|.    |||:.:.                    |:|.:|:.|     .||  
Zfish   218 IDLLPGSSPPRGRVFSLSPPEQAAMN--------------------AYIQESLAT-----GII-- 255

  Fly    86 LKLRHNNLPKLQGFVFL---------ALDIRHL---TIHNSSLAAIEENALSSL-GAGL-TQLDV 136
               |.:..|...||.|:         .:|.|.|   ||.|.....:...|...| ||.: |:|| 
Zfish   256 ---RASTSPAGAGFFFVGKKDGGLRPCIDYRGLNKITIRNRYPLPLMATAFELLQGASIFTKLD- 316

  Fly   137 SLNQMKTVPSQALQHLFHLLILN------------LNHNKITVIH---NNA---FEGL------E 177
                        |::.:||:.:.            ..|.:..|:.   .||   |:.|      :
Zfish   317 ------------LRNAYHLVRIRQGDEWKTAFNTPTGHYEYLVMPFGLTNAPAVFQALINDVLRD 369

  Fly   178 TLEILT-LYENKITQIDPEAFRGLEDHIKRL--NLGGNDLTNIPQKA---------LSILSTLKK 230
            .|.|.. :|.:.|. |..::....|.|:.|:  .|..|.|...|:|.         |..:.|...
Zfish   370 MLNIFVFVYLDDIL-IFSKSMEEHEGHVSRVLQRLLENHLFVKPEKCEFHVSLTKFLGYIVTPGH 433

  Fly   231 LEIQENKIR---------TISEGD-FEGLQSLDSLILAHNMITTVPANVFSHLTLLNSLELE-GN 284
            ||:..:||:         |:.|.. |.|..:.....:.:......|   .:.||....:::| |.
Zfish   434 LEMDPSKIKAVLNWPIPTTVKEVQRFVGFANFYRKFIRNFSSVVAP---LTALTKGGGVKIEWGP 495

  Fly   285 KISVIDKDAFKGLEE-------------NLQYL----------------RLGDNQIHTIP----- 315
            |.:.    ||:.|::             ::.::                |..|.::|...     
Zfish   496 KAAA----AFQDLKDRFTSAPILSIPNPDIPFMVEVDASDVGVGAILSQRNEDGKLHPCAFMSRR 556

  Fly   316 -SEALRPLH--------------RLRH-LDLRNNNINVLAEDAFTGFGDSLTFLNLQK--NDIKV 362
             |.|.|..|              ..|| |:...:...||.:.      .:|.:|...|  |..:.
Zfish   557 LSNAERNYHVGDRELLAVKLALEEWRHWLEGARHPFQVLTDH------KNLEYLQQAKQLNPRQA 615

  Fly   363 LPSLLFENLNSLETL-----NLQNNKLQRI--PQDIMEPV---IDTLRII--------------- 402
            ..||.|.....:.|.     ||:.:.|.|.  |:...:||   |.:.||:               
Zfish   616 RWSLFFNRFQFILTYRPGSKNLKPDALSRAYSPETHEKPVSSIIPSSRIVAPLRWDLEQVVRKAQ 680

  Fly   403 ----DITDNPLNC--------------------SC------------ELTWFPKLLEDLKNK--- 428
                |..:.||..                    :|            ...|:|.:.||:|..   
Zfish   681 TKEPDPGNGPLGALYVPRAVRAQVLQWGHESVLTCHPGSSRTLEFLRRRFWWPSIKEDVKGYVEA 745

  Fly   429 -----DDEMSQKK------------KPLCHMSLDNREYFVQAMP 455
                 ..:.|.::            :|..|:|||    |:..:|
Zfish   746 CQVCCQGKSSHQRPQGLLHPLPVPHRPWSHLSLD----FITGLP 785

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14762NP_001246198.1 leucine-rich repeat 85..105 CDD:275380 5/28 (18%)
LRR_RI 93..384 CDD:238064 80/408 (20%)
leucine-rich repeat 107..129 CDD:275380 7/25 (28%)
leucine-rich repeat 131..154 CDD:275380 4/23 (17%)
LRR_8 154..214 CDD:290566 18/86 (21%)
leucine-rich repeat 155..178 CDD:275380 7/46 (15%)
leucine-rich repeat 179..203 CDD:275380 6/24 (25%)
leucine-rich repeat 204..227 CDD:275380 7/33 (21%)
LRR_8 226..286 CDD:290566 14/70 (20%)
leucine-rich repeat 228..251 CDD:275380 8/32 (25%)
leucine-rich repeat 252..275 CDD:275380 2/22 (9%)
LRR_8 276..335 CDD:290566 16/109 (15%)
leucine-rich repeat 276..300 CDD:275380 6/37 (16%)
leucine-rich repeat 301..324 CDD:275380 7/58 (12%)
leucine-rich repeat 325..349 CDD:275380 5/24 (21%)
LRR_8 349..409 CDD:290566 19/90 (21%)
leucine-rich repeat 350..373 CDD:275380 7/24 (29%)
lrfn4bXP_021333806.1 retropepsin_like 58..144 CDD:133136
RT_LTR 253..429 CDD:238825 43/194 (22%)
RNase_HI_RT_Ty3 525..646 CDD:260006 24/126 (19%)
zf-H2C2 716..749 CDD:324145 5/32 (16%)
rve 772..885 CDD:307008 7/18 (39%)
Chromo 1069..1116 CDD:306815
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I12162
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.