Protein Alignment CG14762 and lingo4a

DIOPT Version :10

• Sequence 1: NP_001246198.1
• Gene: CG14762 / 35768
• FlyBaseID: FBgn0033250
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001076447.1
• Gene: lingo4a / 100005227
• ZFINID: ZDB-GENE-060503-275
• Length: 618
• Species: Danio rerio
• Alignment Length: 323
• Identity: 94/323 - (29%)
• Similarity: 148/323 - (45%)
• Gaps: 34/323 - (10%)

  Fly   124 LSSLGAGL---TQ-LDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILTL 184
            ||::..|:   || |:::.|.:||:.|:....|..|..|:|:.|.:|||...||.||:.|..|.|
Zfish    62 LSAVPEGVPDATQVLNLTYNHLKTLSSRQFFSLRQLRELDLSANMLTVIEVEAFVGLQNLITLRL 126

  Fly   185 YENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEGL 249
            ..|::..|...||.|| .:::.|::..|::..:.......:.:|:|||..||.:..||...|.||
Zfish   127 SRNRLKIIPVGAFSGL-PNVQFLDISENEILVLLDDMFGEMPSLQKLEASENDLVFISNRAFSGL 190

  Fly   250 QSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKISVIDKDAFKGLEE--------------- 299
            .:|..|.|....:||||:..||.||.|..|......::.:..::|:.|:.
Zfish   191 PNLLELRLERCNLTTVPSEAFSRLTGLQHLRFCRLGLTALPNNSFRQLQRLQDLHVSRCPWLHTL 255

  Fly   300 --------NLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLTF--LN 354
                    ||..|.|....:..:|...|..|..||:|||..|.|..:....   .||.|..  |:
Zfish   256 AVNSLIGLNLTSLTLSHCNLSAVPYAPLHHLVYLRYLDLSYNPITTVLSGL---LGDLLRLQELH 317

  Fly   355 LQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPVIDTLRIIDITDNPLNCSCELTW 417
            |....:..:.|..|.||.....||:.:|:|..:.:.... .:.:|.::.:..|||.|.|.|.|
Zfish   318 LVSTGLLHVESGAFRNLAFFRLLNVSDNRLVTLEESAFH-AVGSLEVLRLDGNPLACDCRLLW 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		leucine-rich repeat	107..129	CDD:275380	2/4 (50%)
		LRR	<131..410	CDD:443914	86/307 (28%)
		leucine-rich repeat	131..154	CDD:275380	8/26 (31%)
		leucine-rich repeat	155..178	CDD:275380	11/22 (50%)
		leucine-rich repeat	179..203	CDD:275380	9/23 (39%)
		leucine-rich repeat	204..227	CDD:275380	2/22 (9%)
		leucine-rich repeat	228..251	CDD:275380	11/22 (50%)
		leucine-rich repeat	252..275	CDD:275380	10/22 (45%)
		leucine-rich repeat	276..300	CDD:275380	4/46 (9%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..349	CDD:275380	8/23 (35%)
		leucine-rich repeat	350..373	CDD:275380	7/24 (29%)
lingo4a	NP_001076447.1	LRRNT	41..70	CDD:214470	3/7 (43%)
		leucine-rich repeat	52..72	CDD:275380	3/9 (33%)
		leucine-rich repeat	73..96	CDD:275380	8/22 (36%)
		LRR	75..379	CDD:443914	88/308 (29%)
		leucine-rich repeat	97..120	CDD:275380	11/22 (50%)
		leucine-rich repeat	121..144	CDD:275380	9/23 (39%)
		leucine-rich repeat	145..168	CDD:275380	2/22 (9%)
		leucine-rich repeat	169..192	CDD:275380	11/22 (50%)
		leucine-rich repeat	193..216	CDD:275380	10/22 (45%)
		leucine-rich repeat	217..240	CDD:275380	4/22 (18%)
		leucine-rich repeat	241..288	CDD:275380	7/46 (15%)
		leucine-rich repeat	289..310	CDD:275380	8/23 (35%)
		leucine-rich repeat	313..336	CDD:275380	6/22 (27%)
		leucine-rich repeat	337..356	CDD:275380	4/18 (22%)
		Ig	424..512	CDD:472250
		Ig strand B	442..446	CDD:409353
		Ig strand C	455..459	CDD:409353
		Ig strand E	478..482	CDD:409353
		Ig strand F	492..497	CDD:409353
		Ig strand G	505..508	CDD:409353