DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Odc1 and azin2

DIOPT Version :9

Sequence 1:	NP_477052.2	Gene:	Odc1 / 35766	FlyBaseID:	FBgn0013307	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001015993.2	Gene:	azin2 / 548747	XenbaseID:	XB-GENE-6454420	Length:	458	Species:	Xenopus tropicalis

Alignment Length:	386	Identity:	166/386 - (43%)
Similarity:	244/386 - (63%)	Gaps:	13/386 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FYERELNIRRVIEECDLQRLDQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLA 74
            |..|:| :..:|.|........|..:.||..|.:|...:.|.|||:|||||||||....||::||
Frog    17 FMARDL-MEEIINEVSQTEDRDAFFVADLGDVVKKHLRFLKALPRVKPFYAVKCNSSRGVVKILA 80

  Fly    75 QLGAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHY 139
            :||||||||||.|::||....|:|||||:||||:.:|.:::|.:..|...|.|||.|:.|:..::
Frog    81 ELGAGFDCASKTEIELVQDIGVTPERIIYANPCKQISQIKFAAKTGVQMMTFDNEVELSKVSRNH 145

  Fly   140 PNSNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAKSLELKVTGTSFHVGSGCSELQAYDR 204
            ||:.:::|..::..::...|..|||.... ....|:.:||:|.:.|.|.||||||||::.:||.:
Frog   146 PNARMVLRIATDDSKSSARLSVKFGAPLK-SCRRLLEMAKNLSVDVIGVSFHVGSGCTDSKAYTQ 209

  Fly   205 AIKKAKNLFKFGALLGYDMDFLDIGGGFPGSDD--VKFEKIAESVNTSVQRHFPD-ERVHIIAEP 266
            ||..|:.:|:..:..||:|..|||||||||::|  ::||::|..:|.::..:||: ..|.|||||
Frog   210 AIADARLVFEMASEFGYNMWLLDIGGGFPGTEDSKIRFEEMAGVINPALDLYFPEGSDVQIIAEP 274

  Fly   267 GRFFVAAACTLVCKIHAKREI--------RNEAGKLDTVMYYLNDGVYGSFNCILYDHQVVIAEH 323
            ||::|.:|.:|...|.||:|:        ..|.|....:|||:||||||||||:::||.......
Frog   275 GRYYVTSAFSLAVNIIAKKEVLMEHSGSDDEENGPNKNIMYYVNDGVYGSFNCLVFDHAHPKPIL 339

  Fly   324 YLDNAESLPHLKSLIWGPSCDALDKISEDLHLPNLNRGDLLGFRNMGAYTMPIASAFNGFE 384
            :...:...|...|.:|||:||.||:|:|:|.||..:.||.|.|.||||||:..:|.||||:
Frog   340 HKKPSPDQPLYTSSLWGPTCDGLDQIAENLLLPEHHVGDWLLFENMGAYTIAASSNFNGFQ 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odc1	NP_477052.2	LysA	16..391	CDD:223098	163/380 (43%)
Odc1	NP_477052.2	PLPDE_III_ODC	30..391	CDD:143482	161/366 (44%)
azin2	NP_001015993.2	PLPDE_III_ODC	37..406	CDD:143482	161/365 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2761
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I2407
OMA	1	1.010	-	-		QHG62480
OrthoDB	1	1.010	-	-		D306092at33208
OrthoFinder	1	1.000	-	-		FOG0000435
OrthoInspector	1	1.000	-	-		mtm9417
Panther	1	1.100	-	-	O	PTHR11482
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R297
SonicParanoid	1	1.000	-	-		X335
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110