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Protein Alignment Odc1 and ODC1

DIOPT Version :9

Sequence 1:	NP_477052.2	Gene:	Odc1 / 35766	FlyBaseID:	FBgn0013307	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001274118.1	Gene:	ODC1 / 4953	HGNCID:	8109	Length:	461	Species:	Homo sapiens

Alignment Length:	392	Identity:	178/392 - (45%)
Similarity:	241/392 - (61%)	Gaps:	37/392 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LDQALN------------ICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFD 81
            |||.:|            :.||..:.:|...|.|.|||:.|||||||||...:|:.||..|.|||
Human    24 LDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFD 88

  Fly    82 CASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIV 146
            ||||.|::||....|.|||||:||||:.||.::||..:.|...|.|:|.|:.|:...:|.:.|::
Human    89 CASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVL 153

  Fly   147 RFKSEAKEAQCPLGDKFGCDADVDAAALML-LAKSLELKVTGTSFHVGSGCSELQAYDRAIKKAK 210
            |..::..:|.|.|..|||  |.:..:.|:| .||.|.:.|.|.||||||||::.:.:.:||..|:
Human   154 RIATDDSKAVCRLSVKFG--ATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDAR 216

  Fly   211 NLFKFGALLGYDMDFLDIGGGFPGSDDV--KFEKIAESVNTSVQRHFP-DERVHIIAEPGRFFVA 272
            .:|..||.:|:.|..||||||||||:||  |||:|...:|.::.::|| |..|.|||||||::||
Human   217 CVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVA 281

  Fly   273 AACTLVCKIHAKR-EIRNEAGKLD-------TVMYYLNDGVYGSFNCILYDHQVVIAEHYLDNAE 329
            :|.||...|.||: .::.:.|..|       |.|||:|||||||||||||||     .|.....:
Human   282 SAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDH-----AHVKPLLQ 341

  Fly   330 SLP-----HLKSLIWGPSCDALDKISEDLHLPNLNRGDLLGFRNMGAYTMPIASAFNGFEVPKTL 389
            ..|     :..|.||||:||.||:|.|...||.::.||.:.|.||||||:..||.||||:.| |:
Human   342 KRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRP-TI 405

  Fly   390 YF 391
            |:
Human   406 YY 407

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.