DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Odc1 and RGD1562036

DIOPT Version :9

Sequence 1:	NP_477052.2	Gene:	Odc1 / 35766	FlyBaseID:	FBgn0013307	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_232777.5	Gene:	RGD1562036 / 297899	RGDID:	1562036	Length:	457	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	157/391 - (40%)
Similarity:	230/391 - (58%)	Gaps:	19/391 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RELNIRRVIEECDLQRLDQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLG 77
            |:|.::: |::..:........:.||..:..:.:.:.:.|||:.||||||||:.|.::.:||.||
  Rat    65 RQLVLKK-IQDLSISGHQDPFMVADLDVLASRHQTFLQALPRVWPFYAVKCNNRPSLLLVLAALG 128

  Fly    78 AGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNS 142
            .||||||:.|::.|||..|:|.||||||||:.|||::||....|...|.|:|.|:.||..|:|.:
  Rat   129 TGFDCASQGELEQVLGLGVAPSRIIFANPCKAVSHIQYAARCGVQLLTFDSEEELTKLARHHPGA 193

  Fly   143 NLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAKSLELKVTGTSFHVGSGCSELQAYDRAIK 207
            .||:|.::....:..||..|||... :....|:.:|:.|.|.|.|.||||||.|...|:|.:||.
  Rat   194 RLILRIQTLGGRSTFPLHTKFGARL-LACGRLLQVARELGLAVVGASFHVGSDCHTPQSYRQAIA 257

  Fly   208 KAKNLFKFGALLGYDMDFLDIGGGFPG--SDDVKFEKIAESVNTSVQRHFPD-ERVHIIAEPGRF 269
            ....:|:.|...|:.|..||:||||||  ..:.|||::|..||.::.::||: ..|.:|||||||
  Rat   258 DCHRVFEMGCKAGHQMSLLDLGGGFPGIEGSEAKFEEMARVVNAALAQYFPEGTGVEVIAEPGRF 322

  Fly   270 FVAAACTLVCKIHAKREIRNEAGKLDTVMYYLNDGVYGSFNCILYDH----QVVIAEHYLDNAES 330
            :..:.||....|.||: ...|.|....:.||||:|.||:|...|.|.    .:|:.|     ..|
  Rat   323 YAESVCTAAVNIIAKK-ASLEPGGHRKLAYYLNEGHYGAFRIFLRDPVPRIPIVVKE-----LPS 381

  Fly   331 LPHL-KSLIWGPSCDALDKI-SEDLHLPNLNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLYFQA 393
            .||| ...::||:|||.|:: |.::.||.|:.||.|.|.:||||...::|.||||  |.|..:.|
  Rat   382 DPHLFPCTLYGPTCDAFDRLFSTEVQLPELDVGDWLVFPDMGAYRSTMSSTFNGF--PITTVYDA 444

  Fly   394 I 394
            :
  Rat   445 M 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odc1	NP_477052.2	LysA	16..391	CDD:223098	154/383 (40%)
Odc1	NP_477052.2	PLPDE_III_ODC	30..391	CDD:143482	153/369 (41%)
RGD1562036	XP_232777.5	PLPDE_III_ODC	82..442	CDD:143482	153/368 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341826
Domainoid	1	1.000	201	1.000	Domainoid score	I2910
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2422
OMA	1	1.010	-	-		QHG62480
OrthoDB	1	1.010	-	-		D306092at33208
OrthoFinder	1	1.000	-	-		FOG0000435
OrthoInspector	1	1.000	-	-		mtm8994
orthoMCL	1	0.900	-	-		OOG6_100277
Panther	1	1.100	-	-	O	PTHR11482
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X335
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910